- 関
- See Glucosylceramide
English Journal
- Renal Glycosphingolipid Metabolism Is Dysfunctional in Lupus Nephritis.
- Nowling TK1, Mather AR2, Thiyagarajan T3, Hernández-Corbacho MJ4, Powers TW5, Jones EE5, Snider AJ6, Oates JC7, Drake RR5, Siskind LJ8.
- Journal of the American Society of Nephrology : JASN.J Am Soc Nephrol.2014 Sep 30. pii: ASN.2014050508. [Epub ahead of print]
- Nearly one half of patients with lupus develop glomerulonephritis (GN), which often leads to renal failure. Although nephritis is diagnosed by the presence of proteinuria, the pathology of nephritis can fall into one of five classes defined by different forms of tissue injury, and the mechanisms inv
- PMID 25270066
- Activation of iNKT cells by a distinct constituent of the endogenous glucosylceramide fraction.
- Brennan PJ1, Tatituri RV1, Heiss C2, Watts GF1, Hsu FF3, Veerapen N4, Cox LR5, Azadi P2, Besra GS4, Brenner MB6.
- Proceedings of the National Academy of Sciences of the United States of America.Proc Natl Acad Sci U S A.2014 Sep 16;111(37):13433-8. doi: 10.1073/pnas.1415357111. Epub 2014 Sep 2.
- Invariant natural killer T (iNKT) cells are a specialized T-cell subset that recognizes lipids as antigens, contributing to immune responses in diverse disease processes. Experimental data suggests that iNKT cells can recognize both microbial and endogenous lipid antigens. Several candidate endogeno
- PMID 25197085
- Glucose availability and glycolytic metabolism dictate glycosphingolipid levels.
- Stathem M1, Marimuthu S, O'Neal J, Rathmell JC, Chesney JA, Beverly LJ, Siskind LJ.
- Journal of cellular biochemistry.J Cell Biochem.2014 Aug 21. doi: 10.1002/jcb.24943. [Epub ahead of print]
- Cancer therapeutics has seen an emergence and re-emergence of two metabolic fields in recent years, those of bioactive sphingolipids and glycolytic metabolism. Anaerobic glycolysis and its implications in cancer have been at the forefront of cancer research for over 90 years. More recently, the role
- PMID 25145677
Japanese Journal
- Application of glucosylceramide based liposomes increased the ceramide content in a three-dimensional cultured skin epidermis
- 徳留 嘉寛,遠藤 麻未子,橋本 フミ恵
- Skin Pharmacology and Physiolgy 27(1), 18-24, 2014
- … Glucosylceramide (GlcCer), a ceramide precursor, was applied to three-dimensional skin culture to regulate ceramide. … GlcCer/dimyristoylphosphatidylcholine (DMPC) = 4/4 (molar ratio and GlcCer/DMPC/dimyristoylphosphatidylglycerol (DMPG) = 4/4/1(molar ratio) liposomes were prepared by the thin-layer method. …
- NAID 120005368920
- HPLC-ELSDによる植物由来グルコシルセラミド素材定量分析法の単一試験室妥当性確認
- 宮下 留美子,奈良 昌代,木下 幹朗 [他],間 和彦,中塚 進一,落合 潔,大西 正男
- 日本食品科学工学会誌 : Nippon shokuhin kagaku kogaku kaishi = Journal of the Japanese Society for Food Science and Technology 59(1), 34-39, 2012-01-15
- … ,美容分野へのニーズと共に,健康食品や一般食品,飲料等に広く利用,販売されるようになった食品素材としての植物由来グルコシルセラミド(GlcCer)について,最近市販された標準試薬品(トウモロコシおよびコメからそれぞれ分離された精製GlcCer)を用い,既報の蒸発光散乱検出器付き高速液体クロマトグラフィー(HPLC-ELSD )分析の条件下での定量分析法の単一試験室による妥当性確認を行 …
- NAID 10030333694
- A world of sphingolipids and glycolipids in the brain —Novel functions of simple lipids modified with glucose—
- HIRABAYASHI Yoshio
- Proceedings of the Japan Academy, Series B 88(4), 129-143, 2012
- … Since over 300–400 GSLs are synthesized from glucosylceramide (GlcCer), GlcCer is believed to only serve as the source of most GSLs, including sialic acid-containing GSLs or gangliosides, in the brain. … Recent studies, however, suggest that GlcCer itself plays a role in the heat stress response, as it functions as a glucose donor for the synthesis of cholesterylglucoside, a lipid mediator in heat stress responses in animals. …
- NAID 130001924741
Related Links
- GalNAc(β1-4)Gal(β1-4)GlcCer Gangliotriosylceramide [GL] ガングリオトリオシルセラミド Gangliotriaosylceramide [Lip] ガングリオトリアオシルセラミド Gg 4 Cer / GgOse 4 Cer Gal(β1-3)GalNAc(β1-4)Gal(β1-4)GlcCer [GL, Lip] Lc 3 3 Cer ...
- ... -スからUDP-glucose: N-acylsphingosine glucosyltransferaseにより生成されたグルコシルセラミド(GlcCer)を出発物質とし、これに種々の糖が付加されて生合成される。 セラミドの合成アナログであるD-threo-1-phenyl-2D -PDMP、図 ...
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