DNA依存性DNA・リメラーゼ、DNA指向性DNA・リメラーゼ
- 関
- DNA polymerase
WordNet
- straightforward in means or manner or behavior or language or action; "a direct question"; "a direct response"; "a direct approach"
- having no intervening persons, agents, conditions; "in direct sunlight"; "in direct contact with the voters"; "direct exposure to the disease"; "a direct link"; "the direct cause of the accident"; "direct vote" (同)unmediated
- in precisely the same words used by a writer or speaker; "a direct quotation"; "repeated their dialog verbatim" (同)verbatim
- (of a current) flowing in one direction only; "direct current"
- be in charge of
- being an immediate result or consequence; "a direct result of the accident"
- command with authority; "He directed the children to do their homework"
- direct in spatial dimensions; proceeding without deviation or interruption; straight and short; "a direct route"; "a direct flight"; "a direct hit"
- give directions to; point somebody into a certain direction; "I directed them towards the town hall"
- guide the actors in (plays and films)
- lacking compromising or mitigating elements; exact; "the direct opposite"
- moving from west to east on the celestial sphere; or--for planets--around the sun in the same direction as the Earth
- similar in nature or effect or relation to another quantity; "a term is in direct proportion to another term if it increases (or decreases) as the other increases (or decreases)"
- the 4th letter of the Roman alphabet (同)d
- manageable by a supervising agent; "a directed program of study"
- (often used in combination) having a specified direction; "a positively directed vector"; "goal-directed"
- an enzyme that catalyzes the formation of new DNA and RNA from an existing strand of DNA or RNA
PrepTutorEJDIC
- 『まっすぐな』,一直線の(straight),直進する / (列車などが途中駅に寄らずに)直行 / 直系の / 『直接の』,じかの / 『率直な』,単刀直入の / 全くの,絶対の / 原典どおりの / 『まっすぐに』,直行で / 〈事〉‘を'『指揮する』,監督する / 《文》〈人〉‘に'『命令する』,指図する / 〈人〉‘に'(…への)『道を教える』《+『名』〈人〉+『to』+『名』》 / (…に)〈目・注意・努力など〉‘を'『向ける』《+『名』+『to』(『at, toward』)+『名』(do『ing』)》 / 〈音楽・演劇・映画など〉‘を'『指揮する』,演出する,監督する / (…に)〈手紙など〉‘を'あてる《+『名』+『to』+『名』》
- deuteriumの化学記号
- deoxyribonucleic acidディオキシリボ核酸
Wikipedia preview
出典(authority):フリー百科事典『ウィキペディア（Wikipedia）』「2014/04/25 12:11:38」(JST)
[Wiki en表示]
| DNA-directed DNA polymerase |
| Identifiers |
| EC number |
2.7.7.7 |
| CAS number |
9012-90-2 |
| Databases |
| IntEnz |
IntEnz view |
| BRENDA |
BRENDA entry |
| ExPASy |
NiceZyme view |
| KEGG |
KEGG entry |
| MetaCyc |
metabolic pathway |
| PRIAM |
profile |
| PDB structures |
RCSB PDB PDBe PDBsum |
| Search |
| PMC |
articles |
| PubMed |
articles |
| NCBI |
proteins |
|
DNA-directed DNA polymerase (EC 2.7.7.7, DNA polymerase I, DNA polymerase II, DNA polymerase III, DNA polymerase alpha, DNA polymerase beta, DNA polymerase gamma, DNA nucleotidyltransferase (DNA-directed), DNA nucleotidyltransferase (DNA-directed), deoxyribonucleate nucleotidyltransferase, deoxynucleate polymerase, deoxyribonucleic acid duplicase, deoxyribonucleic acid polymerase, deoxyribonucleic duplicase, deoxyribonucleic polymerase, deoxyribonucleic polymerase I, DNA duplicase, DNA nucleotidyltransferase, DNA polymerase, DNA replicase, DNA-dependent DNA polymerase, duplicase, Klenow fragment, sequenase, Taq DNA polymerase, Taq Pol I, Tca DNA polymerase) is an enzyme with system name deoxynucleoside-triphosphate:DNA deoxynucleotidyltransferase (DNA-directed).[1][2][3][4][5][6] This enzyme catalyses the following chemical reaction
- deoxynucleoside triphosphate + DNAn diphosphate + DNAn+1
Catalyses DNA-template-directed extension of the 3'- end of a DNA strand by one nucleotide at a time.
References
- ^ Bollum, F.J. (1960). "Calf thymus polymerase". J. Biol. Chem. 235: 2399–2403. PMID 13802334.
- ^ Falaschi, A. and Kornberg, A. (1966). "Biochemical studies of bacterial sporulation. II. Deoxy-ribonucleic acid polymerase in spores of Bacillus subtilis". J. Biol. Chem. 241: 1478–1482. PMID 4957767.
- ^ Lehman, I.R., Bessman, M.J., Simms, E.S. and Kornberg, A. (1958). "Enzymatic synthesis of deoxyribonucleic acid. I. Preparation of substrates and partial purification of an enzyme from Escherichia coli". J. Biol. Chem. 233: 163–170. PMID 13563462.
- ^ Richardson, C.C., Schildkraut, C.L., Aposhian, H.V. and Kornberg, A. (1964). "Enzymatic synthesis of deoxyribonucleic acid. XIV. Further purification and properties of deoxyribonucleic acid polymerase of Escherichia coli". J. Biol. Chem. 239: 222–232. PMID 14114848.
- ^ Schachman, H.K., Adler, J., Radding, C.M., Lehman, I.R. and Kornberg, A. (1960). "Enzymatic synthesis of deoxyribonucleic acid. VII. Synthesis of a polymer of deoxyadenylate and deoxythymidylate". J. Biol. Chem. 235: 3242–3249. PMID 13747134.
- ^ Zimmerman, B.K. (1966). "Purification and properties of deoxyribonucleic acid polymerase from Micrococcus lysodeikticus". J. Biol. Chem. 241: 2035–2041. PMID 5946628.
External links
- DNA-directed DNA polymerase at the US National Library of Medicine Medical Subject Headings (MeSH)
UpToDate Contents
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English Journal
- Improving Polymerase Activity with Unnatural Substrates by Sampling Mutations in Homologous Protein Architectures.
- Dunn MR1, Otto C, Fenton KE, Chaput JC1.
- ACS chemical biology.ACS Chem Biol.2016 Feb 17. [Epub ahead of print]
- The ability to synthesize and propagate genetic information encoded in the framework of xeno-nucleic acid (XNA) polymers would inform a wide range of topics from the origins of life to synthetic biology. While directed evolution has produced examples of engineered polymerases that can accept XNA sub
- PMID 26860781
- Assays To Detect the Formation of Triphosphates of Unnatural Nucleotides: Application to Escherichia coli Nucleoside Diphosphate Kinase.
- Matsuura MF1,2, Shaw RW2,3, Moses JD2,3, Kim HJ2,3, Kim MJ2,3, Kim MS2,3, Hoshika S2,3, Karalkar N2,3, Benner SA2,3.
- ACS synthetic biology.ACS Synth Biol.2016 Feb 1. [Epub ahead of print]
- One frontier in synthetic biology seeks to move artificially expanded genetic information systems (AEGIS) into natural living cells and to arrange the metabolism of those cells to allow them to replicate plasmids built from these unnatural genetic systems. In addition to requiring polymerases that r
- PMID 26829203
- DNA Nanoparticles for Improved Protein Synthesis In Vitro.
- Galinis R1, Stonyte G1, Kiseliovas V1, Zilionis R1, Studer S2, Hilvert D2, Janulaitis A1, Mazutis L3.
- Angewandte Chemie (International ed. in English).Angew Chem Int Ed Engl.2016 Feb;55(9):3120-3. doi: 10.1002/anie.201511809. Epub 2016 Jan 28.
- The amplification and digital quantification of single DNA molecules are important in biomedicine and diagnostics. Beyond quantifying DNA molecules in a sample, the ability to express proteins from the amplified DNA would open even broader applications in synthetic biology, directed evolution, and p
- PMID 26821778
Japanese Journal
- Unique subcellular distribution of RPB1 with a phosphorylated C-terminal domain (CTD) in mouse oocytes during meiotic division and its relationship with chromosome separation
- ブタサイトメガロウイルスDNAポリメラーゼのコンセンサスプライマーPCRによる解析(短報)
- The journal of veterinary medical science 61(11), 1253-1255, s・vii, 1999-11
- NAID 110003920266
- Preparation of S-Protected Cysteine-Containing Peptide Thioester and Its Use for the Synthesis of the Barnase-Like Domain in DNA-Directed RNA Polymerase II of Saccharomyces cerevisiae
- Bulletin of the Chemical Society of Japan 68(1), 330-336, 1995-01-15
- NAID 10008885262
★リンクテーブル★
[★]
- 英
- DNA-directed DNA polymerase
- 関
- DNA指向性DNAポリメラーゼ, DNA-dependent DNA polymerase、DNAポリメラーゼ
[★]
- 英
- DNA-directed DNA polymerase
- 関
- DNAポリメラーゼ、DNA依存性DNAポリメラーゼ
[★]
- 指示する、向ける、指揮する、方向づける、指導する、配向する
- 関
- coach、conduct、dictate、direction、directly、guidance、guide、immediate、indicate、indication、instruct、instruction、orient、orientation、point、straightforward、tutorial
[★]
[★]
- 英
- deoxyribonucleic acid
- 同
- デオキシリボ核酸
- 関
- リボ核酸 RNA