Cushing ulcer

クッシング潰瘍

WordNet

1. a circumscribed inflammatory and often suppurating lesion on the skin or an internal mucous surface resulting in necrosis of tissue (同)ulceration
2. United States neurologist noted for his study of the brain and pituitary gland and who identified Cushings syndrome (1869-1939) (同)Harvey Cushing, Harvery Williams Cushing

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1. 潰瘍

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出典(authority):フリー百科事典『ウィキペディア（Wikipedia）』「2016/08/10 01:46:18」(JST)

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Cushing ulcer
Classification and external resources
Specialty	gastroenterology
DiseasesDB	3259

A Cushing ulcer, named after Harvey Cushing, is a gastric ulcer associated with elevated intracranial pressure. It is also called von Rokitansky-Cushing syndrome. Apart from in the stomach, ulcers may also develop in the proximal duodenum and distal esophagus.

Causes

The mechanism of development of Cushing ulcers is thought to be due to direct stimulation of vagal nuclei as a result of increased intracranial pressure. Alternatively, it may also be a direct result of Cushing reaction. Efferent fibers of the vagus nerve then release acetylcholine onto gastric parietal cell M₃ receptors, causing insertion of hydrogen potassium ATPase vesicles into the apical plasma membrane. The end result is increased secretion of gastric acid with eventual ulceration of the gastric mucosa.

See also

• Curling ulcer

References

UpToDate Contents

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• 1. 集中治療室（ICU）におけるストレス潰瘍の予防 stress ulcer prophylaxis in the intensive care unit
• 2. 消化性潰瘍の稀な原因 unusual causes of peptic ulcer disease
• 3. 急性出血性のびらん性胃障害および慢性化学性の胃障害 acute hemorrhagic erosive gastropathy and chronic chemical gastropathy
• 4. 成人における上部消化管出血の主要な原因 major causes of upper gastrointestinal bleeding in adults
• 5. 脳卒中の内科的合併症 medical complications of stroke

English Journal

• Intralesional injection of diprospan is effective for infantile hemangioma.

• Yuan SM1, Zhang M, Guo Y, Cui L, Hong ZJ, Jiang HQ.
• The Journal of craniofacial surgery.J Craniofac Surg.2015 Mar;26(2):422-4. doi: 10.1097/SCS.0000000000001274.
• BACKGROUND: The use of glucocorticoid in infantile hemangioma has remained the main stream for over 30 years. Intralesional corticosteroids got good effects in small-size hemangioma. Here, we introduce a new compound glucocorticoids preparation, Diprospan. Diprospan 1 mL/ampoule contains betamethaso
• PMID 25643331

• Management of periorbital hemangioma by intralesional glucocorticoids and systemic propranolol: a single-center retrospective study.

• Yuan SM1, Cui L1, Guo Y1, Xue CY2, Hong ZJ1, Jiang HQ1.
• International journal of clinical and experimental medicine.Int J Clin Exp Med.2014 Apr 15;7(4):962-7. eCollection 2014.
• Periorbital hemangioma may lead to the vision impairment so effective treatment should be adopted in time. In this study, we made a retrospective analysis of intralesional glucocorticoids and systemic propranolol in the management of periorbital hemangioma. From Jan. 2006 to Dec. 2013, twenty-five c
• PMID 24955168

• Evidence-based medicine: pressure sores.

• Cushing CA1, Phillips LG.
• Plastic and reconstructive surgery.Plast Reconstr Surg.2013 Dec;132(6):1720-32. doi: 10.1097/PRS.0b013e3182a808ba.
• LEARNING OBJECTIVES: After studying this article, the participant should be able to: 1. Cite risk factors for pressure sore development. 2. Detail the pathophysiology of pressure sores. 3. List the types and classification of pressure sores. 4. Consider the various nonsurgical conservative wound man
• PMID 24281597

Japanese Journal

• 医原性クッシング症候群の治療過程で高カルシウム血症が認められた犬の1例(短報)(内科学)

• 中村 桃子,河村 裕子,峯岸(門屋) 美知代,桃井 康行,岩崎 利郎
• The journal of veterinary medical science 66(3), 329-331, 2004-03-25
• 6歳齢避妊済みのパグが皮膚の硬結と潰瘍を主訴に来院した.近医にて脂肪織炎と仮診断され,グルココルチコイドを長期間投与されていた.来院時皮膚に重度の石灰化と深在性膿皮症がみられ,医原性クッシング症と診断してプレドニゾロンを漸減した.中止後著しい高Ca血症が進行し,腎不全により死亡した.剖検では高Ca血症の原因が認められず,石灰化病変からのCaの溶出が高Ca血症の原因と思われた.
• NAID 110003886407

• 中枢神経障害による胃粘膜障害の研究 第1編 ヒト脳血管障害における内視鏡的検討

• 原田 仁史
• 岡山医学会雑誌 98(11-12), 1027-1035, 1986-12-30
• … Acute duodenal ulcer became obvious from the third day after the accident. …
• NAID 120002306447

Related Links

• クッシング潰瘍 クッシングかいよう Cushing ulcer

クッシング潰瘍 クッシングかいよう Cushing ulcer 中枢神経系疾患によって，あるいは頭部の外傷とか手術後に生じる胃・十二指腸潰瘍。 H.クッシングが 1932年に初めて報告した。代表的なストレス潰瘍である。 本文 ...

• Cushing's ulcer definition - MedicineNet - Health and Medical ...

Cushing's ulcer: A type of gastrointestinal ulcer associated with stressful medical conditions of the brain, in particular, trauma (accidents), operations, or strokes. The ulcers occur more commonly in the stomach than the duodenum.

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英

Cushing ulcer

同

Cushing潰瘍

• 脳疾患に関連して見られる急性胃粘膜障害(AGML)　　⇔　　熱傷に関連する胃潰瘍・十二指腸潰瘍はカーリング潰瘍 Curling潰瘍