クラミジア・ムリダルム
WordNet
- a sexually transmitted infection caused by bacteria of the genus Chlamydia
- coccoid rickettsia infesting birds and mammals; cause infections of eyes and lungs and genitourinary tract
Wikipedia preview
出典(authority):フリー百科事典『ウィキペディア（Wikipedia）』「2016/12/30 23:29:40」(JST)
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| Chlamydia muridarum |
| Scientific classification |
| Domain: |
Bacteria |
| Phylum: |
Chlamydiae |
| Class: |
Chlamydiae |
| Order: |
Chlamydiales |
| Family: |
Chlamydiaceae |
| Genus: |
Chlamydia |
| Species: |
C. muridarum |
| Binomial name |
Chlamydia muridarum
Everett et al., 1999[1] |
Chlamydia muridarum is an intracellular bacterial species that at one time belonged to Chlamydia trachomatis. However, C. trachomatis naturally only infects humans and C. muridarum naturally infects only members of the family Muridae (includes both mice and hamsters, Alderton, 1996).
Two strains of Chlamydia muridarum, MoPn (originally named Nigg) and SFPD,[2] have been isolated from mice and hamsters. Glycogen production by both strains has been demonstrated. The chromosome and extrachromosomal plasmid of MoPn have been sequenced.
Chlamydia muridarum MoPn binds mAbs recognizing Chlamydia trachomatis MOMP vs4 core epitope (T)LNPT(IA).[3] DNA sequence analysis indicates that these mAbs should recognize SFPD and that Chlamydia trachomatis B-serogroup mAbs specific for the vs4 epitope IAGAG should recognize SFPD.[4] MoPn was isolated in 1942 from the lungs of asymptomatic albino Swiss mice and was subsequently shown to be capable of producing disease in mice.[5] SFPD was obtained from a hamster, concurrent with a causative agent of proliferative ileitis. MoPn has been shown to be sensitive to sulfadiazine.
Contents
- 1 Genome structure
- 2 References
- 3 Further reading
- 4 External links
Genome structure
The genome of several strains has been sequenced.[6]
References
- ^ Everett, K. D. E.; Bush, R. M.; Andersen, A. A. (1999). "Emended description of the order Chlamydiales, proposal of Parachlamydiaceae fam. nov. and Simkaniaceae fam. nov., each containing one monotypic genus, revised taxonomy of the family Chlamydiaceae, including a new genus and five new species, and standards for the identification of organisms". International Journal of Systematic Bacteriology. 49 (2): 415–440. doi:10.1099/00207713-49-2-415. ISSN 0020-7713. PMID 10319462.
- ^ Zhang, YX.; Fox, JG.; Ho, Y.; Zhang, L.; Stills, HF.; Smith, TF. (Nov 1993). "Comparison of the major outer-membrane protein (MOMP) gene of mouse pneumonitis (MoPn) and hamster SFPD strains of Chlamydia trachomatis with other Chlamydia strains.". Mol Biol Evol. 10 (6): 1327–42. PMID 8277858.
- ^ Peterson, EM.; Cheng, X.; Markoff, BA.; Fielder, TJ.; de la Maza, LM. (Nov 1991). "Functional and structural mapping of Chlamydia trachomatis species-specific major outer membrane protein epitopes by use of neutralizing monoclonal antibodies.". Infect Immun. 59 (11): 4147–53. PMID 1718870.
- ^ Batteiger, BE.; Lin, PM.; Jones, RB.; Van Der Pol, BJ. (Jul 1996). "Species-, serogroup-, and serovar-specific epitopes are juxtaposed in variable sequence region 4 of the major outer membrane proteins of some Chlamydia trachomatis serovars.". Infect Immun. 64 (7): 2839–41. PMID 8698520.
- ^ Nigg, C. (Jan 1942). "AN UNIDENTIFIED VIRUS WHICH PRODUCES PNEUMONIA AND SYSTEMIC INFECTION IN MICE.". Science. 95 (2454): 49–50. doi:10.1126/science.95.2454.49-a. PMID 17773453.
- ^ Read TD, et al. (2000). "Genome sequences of Chlamydia trachomatis MoPn and Chlamydia pneumoniae AR39". Nucleic Acids Res. 28 (6): 1397–406. doi:10.1093/nar/28.6.1397. PMC 111046. PMID 10684935.
Further reading
- Caldwell, Harlan D.; Sturdevant, Gail L. (October 2014). "Innate immunity is sufficient for the clearance of Chlamydia trachomatis from the female mouse genital tract". Pathogens and Disease. 72 (1): 70–73. doi:10.1111/2049-632X.12164.
- Campbell, Jessica; Huang, Yumeng; Liu, Yuanjun; Schenken, Robert; Arulanandam, Bernard; Zhong, Guangming (July 1, 2014). "Bioluminescence Imaging of Chlamydia muridarum Ascending Infection in Mice". PLOS. 9: e101634. doi:10.1371/journal.pone.0101634.
External links
- Type strain of Chlamydia muridarum at BacDive - the Bacterial Diversity Metadatabase
UpToDate Contents
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English Journal
- Involvement of Lysosome Membrane Permeabilization and Reactive Oxygen Species Production in the Necrosis Induced by Chlamydia muridarum Infection in L929 Cells.
- Chen L1, Wang C1, Li S1, Yu X1, Liu X1, Ren R1, Liu W2, Zhou X3, Zhang X1, Zhou X1.
- Journal of microbiology and biotechnology.J Microbiol Biotechnol.2016 Apr 28;26(4):790-8. doi: 10.4014/jmb.1510.10082.
- Chlamydiae, obligate intracellular bacteria, are associated with a variety of human diseases. The chlamydial life cycle undergoes a biphasic development: replicative reticulate bodies (RBs) phase and infectious elementary bodies (EBs) phase. At the end of the chlamydial intracellular life cycle, EBs
- PMID 26838343
- Computational modeling of TC0583 as a putative component of the Chlamydia muridarum V-type ATP synthase complex and assessment of its protective capabilities as a vaccine antigen.
- Tifrea DF1, Barta ML2, Pal S1, Hefty PS2, de la Maza LM3.
- Microbes and infection / Institut Pasteur.Microbes Infect.2016 Apr;18(4):245-53. doi: 10.1016/j.micinf.2015.12.002. Epub 2015 Dec 17.
- Numerous Chlamydia trachomatis proteins have been identified as potential subunit vaccines, of which the major outer-membrane protein (MOMP) has, so far, proven the most efficacious. Recently, subunit A of the V-type ATP synthase (ATPase; TC0582) complex was shown to elicit partial protection agains
- PMID 26706820
- IgA modulates respiratory dysfunction as a sequela to pulmonary chlamydial infection as neonates.
- Lanka GK1, Yu JJ1, Gong S2, Gupta R1, Mustafa SB3, Murthy AK4, Zhong G2, Chambers JP1, Guentzel MN1, Arulanandam BP5.
- Pathogens and disease.Pathog Dis.2016 Apr;74(3). pii: ftv121. doi: 10.1093/femspd/ftv121. Epub 2016 Jan 10.
- Neonatal Chlamydia lung infections are associated with serious sequelae such as asthma and airway hyper-reactivity in children and adults. Our previous studies demonstrated the importance of Th-1 type cytokines, IL-12 and IFN-γ in protection against neonatal pulmonary chlamydial challenge; however,
- PMID 26755533
Related Links
- Classification Higher order taxa Bacteria; Chlamydiae/Verrucomicrobia group; Chlamydiae; Chlamydiae (class); Chlamydiales; Chlamydiaceae; Chlamydia Genus and Species Chlamydia muridarum nigg (1) Description and significance ...
- Chlamydia [klah-mid´e-ah] a widespread genus of gram-negative, nonmotile bacteria. They are obligate intracellular parasites that are totally dependent on the host cell for energy in the form of adenosine triphosphate (ATP), which they ...
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