同: チャイルド・ピュー分類

WordNet

write a musical score for
a slight surface cut (especially a notch that is made to keep a tally) (同)scotch
a number that expresses the accomplishment of a team or an individual in a game or contest; "the score was 7 to 0"
an amount due (as at a restaurant or bar); "add it to my score and Ill settle later"
the act of scoring in a game or sport; "the winning score came with less than a minute left to play"
grounds; "dont do it on my account"; "the paper was rejected on account of its length"; "he tried to blame the victim but his success on that score was doubtful" (同)account
a written form of a musical composition; parts for different instruments appear on separate staves on large pages; "he studied the score of the sonata" (同)musical score
a set of twenty members; "a score were sent out but only one returned"
the facts about an actual situation; "he didnt know the score"
gain points in a game; "The home team scored many times"; "He hit a home run"; "He hit .300 in the past season" (同)hit, tally, rack_up
make underscoring marks (同)mark
make small marks into the surface of; "score the clay before firing it" (同)nock, mark
get a certain number or letter indicating quality or performance; "She scored high on the SAT"; "He scored a 200"
an immature childish person; "he remained a child in practical matters as long as he lived"; "stop being a baby!" (同)baby
a human offspring (son or daughter) of any age; "they had three children"; "they were able to send their kids to college" (同)kid
a young person of either sex; "she writes books for children"; "theyre just kids"; "`tiddler is a British term for youngster" (同)kid, youngster, minor, shaver, nipper, small_fry, tiddler, tike, tyke, fry, nestling
a member of a clan or tribe; "the children of Israel"

PrepTutorEJDIC

(ゲーム・競技の)『スコア』,得点記録 / (ゲーム・競技の)『得点』 / (試験の)点数,評点 / 《おもに文》20[の単位] / 《複数形で》多数(の…)《+『of』+『名』》 / 《まれ》勘定,借金 / 《単数形で》理由,根拠,原因 / (また『score mark』)刻み目,線,印 / 総譜,楽譜 / (ゲーム・競技で)〈点数〉‘を'『得点する』 / 〈競技〉‘の'得点を記録する / 〈得点〉‘を'〈人〉‘に'与える《+『名』〈人〉+『名』〈得点〉=+『名』〈得点〉+『to』(『for』)+『名』〈人〉》 / 〈試験〉‘を'採点する;(試験で)…‘の'点をとる《+『名』+『on』+『名』》 / (…で)…‘に'刻み目(印)をつける,線をひく《+『名』+『with』+『名』》 / 《米話》…‘を'こきおろす,酷評する / 《通例受動態で》(…のために)〈音楽〉‘を'作曲(編曲)する《+『for』+『名』》 / (ゲーム・競技で)『得点する』 / 優勢となる,成功する / 《俗》〈男が〉(女を)くどき落とす《+『with』+『名』》 / 《俗》麻薬を売う
(おとなに対して)『子供』,幼児,児童;(小学・中学・高校の)児童 / (親に対して)子,子孫;息子,娘 / (ある環鏡・時代の)影響を受けて生まれた人,(…の)申し子《+『of』+『名』》 / (頭脳・空想などが)産み出したものの,所産《+『of』+『名』》
plutoniumの化学記号

Wikipedia preview

出典(authority):フリー百科事典『ウィキペディア（Wikipedia）』「2015/08/22 10:41:33」(JST)

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In medicine (gastroenterology), the Child-Pugh score (sometimes the Child-Turcotte-Pugh score) is used to assess the prognosis of chronic liver disease, mainly cirrhosis. Although it was originally used to predict mortality during surgery, it is now used to determine the prognosis, as well as the required strength of treatment and the necessity of liver transplantation.

Scoring

The score employs five clinical measures of liver disease. Each measure is scored 1-3, with 3 indicating most severe derangement.^[1]

Measure	1 point	2 points	3 points
Total bilirubin, μmol/l (mg/dl)	<34 (<2)	34-50 (2-3)	>50 (>3)
Serum albumin, g/dl	>3.5	2.8-3.5	<2.8
Prothrombin time, prolongation (secs)	<4.0	4.0-6.0	> 6.0
Ascites	None	Mild	Moderate to Severe
Hepatic encephalopathy	None	Grade I-II (or suppressed with medication)	Grade III-IV (or refractory)

Different textbooks and publications use different measures. Some older reference works substitute PT prolongation for INR.

In primary sclerosing cholangitis (PSC) and primary biliary cirrhosis (PBC), the bilirubin references are changed to reflect the fact that these diseases feature high conjugated bilirubin levels. The upper limit for 1 point is 68 μmol/l (4 mg/dl) and the upper limit for 2 points is 170 μmol/l (10 mg/dl).^{[citation needed]}

Interpretation

Chronic liver disease is classified into Child-Pugh class A to C, employing the added score from above.^[1]

Points	Class	One year survival	Two year survival
5-6	A	100%	85%
7-9	B	81%	57%
10-15	C	45%	35%

Related scoring systems

MELD Score

History

Dr C.G. Child and Dr J.G. Turcotte of the University of Michigan first proposed the scoring system in 1964 in a textbook on liver disease.^[2] It was modified by Pugh et al in 1972 in a report on surgical treatment of bleeding from esophageal varices.^[3] They replaced Child's criterion of nutritional status with the prothrombin time or INR, and assigned scores of 1-3 to each variable.^[1]

References

^ ^a ^b ^c Cholongitas, E; Papatheodoridis, GV; Vangeli, M; Terreni, N; Patch, D; Burroughs, AK (Dec 2005). "Systematic review: The model for end-stage liver disease--should it replace Child-Pugh's classification for assessing prognosis in cirrhosis?". Alimentary pharmacology & therapeutics 22 (11-12): 1079–89. doi:10.1111/j.1365-2036.2005.02691.x. PMID 16305721.
^ Child CG, Turcotte JG (1964). "Surgery and portal hypertension". In Child CG. The liver and portal hypertension. Philadelphia: Saunders. pp. 50–64.
^ Pugh RN, Murray-Lyon IM, Dawson JL, Pietroni MC, Williams R (1973). "Transection of the oesophagus for bleeding oesophageal varices". The British journal of surgery 60 (8): 646–9. doi:10.1002/bjs.1800600817. PMID 4541913.

External links

Child-Pugh calculator from LiverpoolMedics

UpToDate Contents

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1. 成人における肝硬変：合併症、全般的マネージメント、および予後の概要 cirrhosis in adults overview of complications general management and prognosis
2. 計算ツール：肝疾患重症度のためのChild Pugh分類 calculator child pugh classification for severity of liver disease
3. Model for End-stage Liver Disease (MELD)
4. 肝疾患患者における手術リスクの評価 assessing surgical risk in patients with liver disease
5. 計算機：肝疾患重症度ためのChild Pugh分類（SI単位） calculator child pugh classification for severity of liver disease si units

English Journal

Radiologic response to transcatheter hepatic arterial chemoembolization and clinical outcomes in patients with hepatocellular carcinoma.

Kim CJ, Kim HJ, Park JH, Park DI, Cho YK, Sohn CI, Jeon WK, Kim BI, Kim MJ.Author information Department of Internal Medicine, Kangbuk Samsung Hospital, Sungkyunkwan University, Seoul, Korea.AbstractBACKGROUND & AIMS: The current study analysed the association between radiologic tumour response and survival times of patients with hepatocellular carcinoma (HCC) who were treated with transcatheter hepatic arterial chemoembolization (TACE).
Liver international : official journal of the International Association for the Study of the Liver.Liver Int.2014 Feb;34(2):305-12. doi: 10.1111/liv.12270. Epub 2013 Jul 25.
BACKGROUND & AIMS: The current study analysed the association between radiologic tumour response and survival times of patients with hepatocellular carcinoma (HCC) who were treated with transcatheter hepatic arterial chemoembolization (TACE).METHODS: Among 493 consecutive patients presenting to
PMID 23890360

Clinical findings in 19 cases of invasive pulmonary aspergillosis with liver cirrhosis.

Chen J, Yang Q, Huang J, Li L.Author information State Key Laboratory for Diagnosis and Treatment of Infectious Diseases, First Affiliated Hospital, College of Medicine, Zhejiang University, Hangzhou, China. ljli@zju.edu.cn.AbstractBACKGROUND: Aspergillus infection was mostly reported with high mortality rates and a bad prognosis in immunocompromised patients, but data were lacking on the clinical characteristics of aspergillus infection in liver cirrhosis. The aim of this study was to retrospectively assess the morbidity and mortality rate, clinical manifestation, risk factors, and medication of invasive pulmonary aspergillosis (IPA) in liver cirrhosis in The First Affiliated Hospital, College of Medicine, Zhejiang University.
Multidisciplinary respiratory medicine.Multidiscip Respir Med.2014 Jan 8;9(1):1. doi: 10.1186/2049-6958-9-1.
BACKGROUND: Aspergillus infection was mostly reported with high mortality rates and a bad prognosis in immunocompromised patients, but data were lacking on the clinical characteristics of aspergillus infection in liver cirrhosis. The aim of this study was to retrospectively assess the morbidity and
PMID 24401649

Japanese Journal

B型肝硬変に対するラミブジン投与の有用性の検討

土島睦,林伸彦,斎藤隆,白枝昌子,岡村英之,矢野博一,福羅匡普,川原弘,高瀬修二郎
金沢医科大学雑誌 30(4), 577-583, 2005-12
… B型慢性肝炎に対するラミブジン(Lamivudine)の効果が確認されてきているので,非代償性B型肝硬変7例に対しラミブジン100mgを連日投与し,その有用性について各種予後予測式(Child-Turcotte-Pugh score, Model for End-Stage Liver Disease score,血液生化学所見からの肝移植スコアー,F Index)を指標に検討した。 …
NAID 110006198490