カンプトテカ属、Camptotheca属
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出典(authority):フリー百科事典『ウィキペディア（Wikipedia）』「2015/08/08 17:46:08」(JST)
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| Happy tree |
|
| Camptotheca acuminata |
| Scientific classification |
| Kingdom: |
Plantae |
| (unranked): |
Angiosperms |
| (unranked): |
Eudicots |
| (unranked): |
Asterids |
| Order: |
Cornales |
| Family: |
Cornaceae (Nyssaceae) |
| Genus: |
Camptotheca
Decne. |
| Species |
|
Camptotheca acuminata
Camptotheca lowreyana
|
|
Wikimedia Commons has media related to Camptotheca. |
Camptotheca (happy tree, cancer tree, or tree of life) is a genus of medium-sized deciduous trees growing to 20 metres (66 ft) tall, native to southern China and Tibet. The genus is usually included in the tupelo family Nyssaceae, but sometimes included (with the tupelos) in the dogwood family Cornaceae.
The name "happy tree" is a direct translation of the Chinese name xǐ shù (Simplified Chinese:喜树).
There are two species:
- Camptotheca acuminata Decne.
- Camptotheca lowreyana S.Y.Li
The bark and stems of C. acuminata contain the alkaloid camptothecin.[1] Several chemical derivatives of camptothecin are under investigation for or used as drugs for cancer treatment, including irinotecan, topotecan, rubitecan.[2]
C. acuminata also contains the chemical compounds trifolin and hyperoside.[1]
References
- ^ a b Li, S.; Zhang, Z.; Cain, A.; Wang, B.; Long, M.; Taylor, J. (2005). "Antifungal Activity of Camptothecin, Trifolin, and Hyperoside Isolated from Camptotheca acuminata". Journal of Agricultural and Food Chemistry 53 (1): 32–37. doi:10.1021/jf0484780. PMID 15631505.
- ^ G. Samuelsson (2004). Drugs of Natural Origin: a Textbook of Pharmacognosy (5 ed.). Stokkholm: Swedish pharmaceutical press. ISBN 91-974318-4-2.
English Journal
- 10-Hydroxycamptothecin induces apoptosis in human neuroblastoma SMS-KCNR cells through p53, cytochrome c and caspase 3 pathways.
- Yuan ZF, Tang YM, Xu XJ, Li SS, Zhang JY.
- Neoplasma.Neoplasma.2016;63(1):72-9. doi: 10.4149/neo_2016_009.
- Neuroblastoma (NB), the most common extracranial solid tumor in childhood, remains one of the most challenging types of cancer to treat. Therefore, the search for novel effective drugs for its treatment is essential. The present study used 10-hydroxycamptothecin (HCPT), which is a naturally occurri
- PMID 26639236
- A novel 10-hydroxycamptothecin-glucoside from the fruit of Camptotheca acuminata.
- Guo Q1, Yuan Q1.
- Natural product research.Nat Prod Res.2015 Nov 26:1-7. [Epub ahead of print]
- Glycosides were isolated from the fruit of Camptotheca acuminata and identified using NMR, MS, UV and IR spectrometries. 10-O-(1-β-D-glycosyl) camptothecin (1) was identified for the first time in a natural material. In addition, compounds 2-4 were firstly reported from the fruits of C. acuminata a
- PMID 26609763
- Simultaneous determination of camptothecin and 10-hydroxycamptothecine in the Camptotheca acuminate, its medicinal preparation and in rat plasma by liquid chromatography with fluorescence detection.
- Li P1,2, Chen Q2, Yu F2, Xie X1, Wang S1,2.
- Biomedical chromatography : BMC.Biomed Chromatogr.2015 Oct;29(10):1522-6. doi: 10.1002/bmc.3452. Epub 2015 Feb 27.
- Camptotheca acuminata Decne is an important medicinal plant that contains various cytotoxic alkaloids, such as camptothecine (CPT) and 10-hydroxycamptothecine (HCPT). A rapid and sensitive liquid chromatography with fluorescence detection (LC-FLD) method for the quantification of CPT and HCPT is des
- PMID 25728326
Japanese Journal
- Search of new cytotoxic crude materials against human oral squamous cell carcinoma using 1H NMR-based metabolomics
- 鈴木 龍一郎,松野 慎平,坂上 宏,Okada Yoshihito,白瀧 義明
- Anticancer Research 34(8), 4117-4120, 2014-08
- … Results: Among 24 plant extracts, Camptotheca acuminate leaf, a well-known source for camptothecin, showed the highest TS value (88.3), followed by Vitis s.p.p. …
- NAID 120005538072
- Rhizobium kunmingense sp. nov., isolated from rhizosphere soil of Camptotheca acuminata Decne
- Shen Lei,Zheng Long-Peng,Liu Huan,Liu Rui,Zhang Ke-Yun,Lai Ren
- The Journal of General and Applied Microbiology 56(2), 143-149, 2010
- … Strain LXD30T was isolated from rhizosphere soil of a plant of the species <I>Camptotheca acuminata </I>Decne which is native to warm, humid stream banks in southern China. …
- NAID 130004449281
- Efficient Rooting and Root Development after Transfer of Regenerated Plantlets of Camptotheca acuminate
- Eurasian Journal of Forest Research 10(2), 179-184, 2007-12
- Articles
- NAID 80017958095
Related Links
- Research Topics, Research Grants, Publications, Scientific Experts about camptotheca ... Yan Pi State Key Laboratory of Genetic Engineering, School of Life Sciences, Morgan Tan International Center for Life Sciences, Fudan ...
- Camptotheca Contents 1 Information 1.1 Cytochrome P450 2 Family/Genus Description 3 Links 3.1 Images 3.2 Trivia Information Cytochrome P450 'A' indicates CYP families in Arabidopsis. CYP73 A CYP84 A CYP98 A BY ) ...
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