White matter disturbance in the ventral prefrontal cortex (vPFC) in major depressive disorder (MDD) has been noted with diffusion tensor imaging (DTI). However, the cellular and molecular pathology of prefrontal white matter in MDD and potential influence of antidepressant medications is not fully u
Molecular neurobiology.Mol Neurobiol.2015 Jun;51(3):1395-416. doi: 10.1007/s12035-014-8817-3. Epub 2014 Aug 2.
Myelin is the functional implication of oligodendrocytes (OLs), which is involved in insulation of axons and promoting rapid propagation of action potential in the brain. OLs are derived from oligodendrocyte progenitor cells (OPCs), which proliferate, differentiate, and migrate throughout the centra
Neurotoxocarosis alters myelin protein gene transcription and expression.
Heuer L1, Beyerbach M, Lühder F, Beineke A, Strube C.
Parasitology research.Parasitol Res.2015 Jun;114(6):2175-86. doi: 10.1007/s00436-015-4407-1. Epub 2015 Mar 17.
Neurotoxocarosis is an infection of the central nervous system caused by migrating larvae of the common dog and cat roundworms (Toxocara canis and Toxocara cati), which are zoonotic agents. As these parasites are prevalent worldwide and neuropathological and molecular investigations on neurotoxocaro
Hexachlorophene and Cuprizone Induce the Spongy Change of the Developing Rat Brain by Different Mechanisms: The Role of 2', 3'-Cyclic Nucleotide 3'-Phosphodiesterase (CNPase)
Journal of Veterinary Medical Science 74(7), 837-843, 2012
… On day 12, cerebral cortex oligodendroglia were stained strongly by anti-CNPase. … Cerebral cortex oligodendroglia were stained strongly by anti-CNPase on days 3 to 8 and decreased to the control levels by day 24 (16 days after dosing ceased). … These findings suggest that CNPase expression was induced in the course of restoration following HCP-induced insults to oligodendroglia and the myelin sheath, and in the course of demyelination by CPZ-induced damage to oligodendroglia. …
Differential expression of protease M/neurosin in oligodendrocytes and their progenitors in an animal model of multiple sclerosis
吉田 成孝,Terayama R,Bando Y,Jiang YP,Mitrovic B
Neuroscience Letters 382(1-2), 82-87, 2005-07
… Combined in situ hybridization and immunohistochemistry demonstrated that most of the cells expressing protease M/neurosin mRNA within control spinal cord showed immunoreactivity for CNPase or NG2, cell-specific markers for oligodendrocytes and their progenitors, respectively. …
Expression of the non-compact myelin protein 2′, 3′-cyclic nucleotide 3′-phosphodiesterase (CNPase) in olfactory bulb ensheathing glia from explant cultures
SANTOS-SILVA Alessandra,CAVALCANTE Leny A.
Neuroscience research : the official journal of the Japan Neuroscience Society 40(2), 189-193, 2001-06-01
Buy CNPase antibodies from Santa Cruz. Select a CNPase antibody from 6 monoclonal and 4 polyclonal antibodies. CNPase si/shRNA gene silencer products also available. ... HOVERcruz ,を紹介します。 a unique system for ...