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1. 脳血管性認知症の病因、臨床症状、および診断etiology clinical manifestations and diagnosis of vascular dementia [show details]
… cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL),… vascular dementia syndrome include Binswanger disease and subcortical ischemic vascular dementia . Although the subcortical changes are obvious,…
2. パーキンソン病の診断および鑑別診断diagnosis and differential diagnosis of parkinson disease [show details]
…lethargica or Economo encephalitis, HIV/AIDS, neurosyphilis, prion disease, progressive multifocal leukoencephalopathy, toxoplasmosis). Cerebrovascular disease. Generally, the clinical history, associated … particularly multiple lacunar infarcts in the basal ganglia and/or Binswanger disease,…
3. 進行性多巣性白質脳症：疫学、臨床症状、および診断progressive multifocal leukoencephalopathy epidemiology clinical manifestations and diagnosis [show details]
… multifocal leukoencephalopathy (PML) is a severe demyelinating disease of the central nervous system that is caused by reactivation of the polyomavirus JC (JC virus) .… preferentially to the periventricular areas and the subcortical white matter,…
4. 皮質下梗塞および白質脳症を伴う常染色体優性脳動脈症（CADASIL）cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy cadasil [show details]
… Cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL) is an autosomal dominantly inherited angiopathy caused by mutations in the NOTCH3 gene on chromosome …
5. ヘロイン吸入による白質脳症（chasing the dragon）leukoencephalopathy due to heroin inhalation chasing the dragon [show details]
… spongiform degeneration with relative sparing of subcortical U-fibers; demyelination is not a prominent feature. The diagnosis of heroin inhalation leukoencephalopathy is clinical, and is supported by the characteristic …

English Journal

An updated diagnostic approach to subtype definition of vascular parkinsonism - Recommendations from an expert working group.

Rektor I, Bohnen NI, Korczyn AD, Gryb V, Kumar H, Kramberger MG, de Leeuw FE, Pirtošek Z, Rektorová I, Schlesinger I, Slawek J, Valkovič P, Veselý B.
Parkinsonism & related disorders. 2018 04;49()9-16.
This expert working group report proposes an updated approach to subtype definition of vascular parkinsonism (VaP) based on a review of the existing literature. The persistent lack of consensus on clear terminology and inconsistent conceptual definition of VaP formed the impetus for the current expe
PMID 29310988

Biomarkers identify the Binswanger type of vascular cognitive impairment.

Barry Erhardt E, Pesko JC, Prestopnik J, Thompson J, Caprihan A, Rosenberg GA.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism. 2018 03;()271678X18762655.
Binswanger's disease is a form of subcortical ischemic vascular disease (SIVD-BD) with extensive white matter changes. To test the hypothesis that biomarkers could improve classification of SIVD-BD, we recruited 62 vascular cognitive impairment and dementia (VCID) patients. Multimodal biomarkers wer
PMID 29513153

Binswanger's disease: biomarkers in the inflammatory form of vascular cognitive impairment and dementia.

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Journal of neurochemistry. 2018 03;144(5)634-643.
Vascular cognitive impairment and dementia (VCID) is a major public health concern because of the increased incidence of vascular disease in the aging population and the impact of vascular disease on Alzheimer's disease. VCID is a heterogeneous group of diseases for which there are no proven treatme
PMID 28902409

Japanese Journal

CARASIL (特集続・日本人の発見した神経疾患)

福武敏夫
Brain and nerve 63(2), 99-108, 2011-02
NAID 40018721580

シンポジウム０３‐１　神経難病の克服‐単一遺伝子病からのアプローチ‐　ＣＡＲＡＳＩＬ‐臨床概念の確立‐

福武敏夫
臨床神経学 50(11), 849-851, 2010
… CARASIL (Cerebral autosomal recessive arteriopathy with subcortical infarcts and leukoencephalopathy) is the second known single-gene disorder directly affecting cerebral small vessels. …
NAID 130004504654