WordNet
- marked strangeness as a consequence of being abnormal (同)freakishness
- behavior that breaches the rule or etiquette or custom or morality (同)irregularity
- an abnormal physical condition resulting from defective genes or developmental deficiencies (同)abnormalcy
- retardation sufficient to fall outside the normal range of intelligence (同)mental defectiveness
- the 2nd letter of the Roman alphabet (同)b
- the blood group whose red cells carry the B antigen (同)type_B, group B
- an agranulocytic leukocyte that normally makes up a quarter of the white blood cell count but increases in the presence of infection (同)lymph cell
PrepTutorEJDIC
- 〈U〉異常,変則 / 〈U〉異常なもの(事件)
UpToDate Contents
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English Journal
- Single arm NCRI phase II study of CHOP in combination with Ofatumumab in induction and maintenance for patients with newly diagnosed Richter's syndrome.
- Eyre TA, Clifford R, Roberts C, Boyle L, Francis A, Schuh A, Dutton SJ.
- BMC cancer.BMC Cancer.2015 Feb 13;15:52. doi: 10.1186/s12885-015-1048-9.
- BACKGROUND: Transformation of B-cell chronic lymphocytic leukaemia (B-CLL) to diffuse large B cell lymphoma (DLBCL) (Richter's syndrome (RS)) is a rare (2-15% of patients) but catastrophic complication of B-CLL. Dose-intense chemotherapy regimens investigated in small single institution trials, but
- PMID 25775024
- Foxp3+ regulatory T cells ensure B lymphopoiesis by inhibiting the granulopoietic activity of effector T cells in mouse bone marrow.
- Kim S1, Park K, Choi J, Jang E, Paik DJ, Seong RH, Youn J.
- European journal of immunology.Eur J Immunol.2015 Jan;45(1):167-79. doi: 10.1002/eji.201444532. Epub 2014 Dec 1.
- Foxp3(+) Treg cells are crucial for maintaining T-cell homeostasis, but their role in B-cell homeostasis remains unclear. Here, we found that Foxp3 mutant scurfy mice had fewer B-lineage cells and progenitors, including common lymphoid progenitors and lymphoid-primed multipotent progenitors, but hig
- PMID 25348202
- Activation-induced necroptosis contributes to B-cell lymphopenia in active systemic lupus erythematosus.
- Fan H1, Liu F1, Dong G1, Ren D1, Xu Y1, Dou J1, Wang T1, Sun L2, Hou Y3.
- Cell death & disease.Cell Death Dis.2014 Sep 11;5:e1416. doi: 10.1038/cddis.2014.375.
- B-cell abnormality including excessive activation and lymphopenia is a central feature of systemic lupus erythematosus (SLE). Although activation threshold, auto-reaction and death of B cells can be affected by intrinsical and/or external signaling, the underlying mechanisms are unclear. Herein, we
- PMID 25210799
Japanese Journal
- 北郡 宏次,川端 大介
- 日本臨床免疫学会会誌 = Japanese journal of clinical immunology 35(6), 495-502, 2012-12-31
- NAID 10031147893
- B cell abnormality in systemic lupus erythematosus
- 北郡 宏次,川端 大介
- 日本臨床免疫学会会誌 35(6), 495-502, 2012
- … B cells play central roles in pathogenesis of SLE through autoantibody production, autoantigen-presentation, cytokine production and activation of cognate T cells. … Recently, a specific subset of B cells, which exerts immunoregulatory properties via IL-10 production was identified, and dysfunction of these B cells might involved in the pathogenesis of SLE. …
- NAID 130003364147
- 胸腺腫患者の免疫異常の検討:—リンパ球の動態を中心として—
- 中田 安成 [他],近藤 昭,片岡 幹男,高杉 健太,三戸 敏正,大熨 泰亮,木村 郁郎
- 臨床血液 21(2), 189-194, 1980
- … The average of circulating lymphocyte counts of the thymoma patients was 2986/cmm and was higher than normal. … There was an increase in the number of non-T and non-B lymphocyte (null-lymphocyte). … Both counts of T and B-lymphocytes were within normal value. …
- NAID 130004498178
Related Links
- The Journal of International Medical Research 2011; 39: 86 –95 86 Correlation between B Lymphocyte Abnormality and Disease Activity in Patients with Idiopathic Membranous Nephropathy B W ANG, K Z UO, Y W U, Q H UANG, W ...
- Introduction Systemic lupus erythematosus (SLE) is an autoimmune disorder with heterogeneous clinical manifestations characterized by B lymphocyte hyper-reactivity and formation of pathogenic auto-antibodies (Ab).
★リンクテーブル★
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- 英
- B-lymphocyte abnormality
[★]
- 関
- aberrant、aberrantly、aberration、abnormal、abnormally、anomalous、anomalously、anomaly、defect、deformity、deviant、deviation、extraordinarily、extraordinary、malformation、malformed、teratologic、unusual、unusually
[★]
- Mg2+存在下でC3, B, Dが反応してC3bBbとなり、これがC3転換酵素(C3bBb)あるいはC5転換酵素(C3bBb3b)を形成する。これらはP(properdin)と結合して活性化し、それぞれC3、C5を活性化する
[★]
リンパ球
- 同
- lymphocytes&development