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- 1. 認知症の予防 prevention of dementia
English Journal
- A study on the association between infectious burden and Alzheimer's disease.
- Bu XL1, Yao XQ1, Jiao SS1, Zeng F1, Liu YH1, Xiang Y1, Liang CR1, Wang QH1, Wang X1, Cao HY1, Yi X1, Deng B1, Liu CH1, Xu J1, Zhang LL1, Gao CY1, Xu ZQ1, Zhang M1, Wang L1, Tan XL2, Xu X3, Zhou HD1, Wang YJ1.
- European journal of neurology.Eur J Neurol.2015 Dec;22(12):1519-25. doi: 10.1111/ene.12477. Epub 2014 Jun 9.
- BACKGROUND AND PURPOSE: Previous studies suggested that the overall burden of prior infections contributes to cardiovascular diseases and stroke. In the present study, the association between infectious burden (IB) and Alzheimer's disease (AD) was examined.METHODS: Antibody titers to common infectio
- PMID 24910016
- G206D Mutation of Presenilin-1 Reduces Pen2 Interaction, Increases Aβ42/Aβ40 Ratio and Elevates ER Ca(2+) Accumulation.
- Chen WT1,2,3, Hsieh YF2, Huang YJ4, Lin CC2, Lin YT2, Liu YC5, Lien CC5,6, Cheng IH7,8,9,10,11.
- Molecular neurobiology.Mol Neurobiol.2015 Dec;52(3):1835-49. doi: 10.1007/s12035-014-8969-1. Epub 2014 Nov 15.
- Early-onset familial Alzheimer's disease (AD) is most commonly associated with the mutations in presenilin-1 (PS1). PS1 is the catalytic component of the γ-secretase complex, which cleaves amyloid precursor protein to produce amyloid-β (Aβ), the major cause of AD. Presenilin enhancer 2 (Pen2) is
- PMID 25394380
- Inhibitory effect of human serum albumin on Cu-induced Aβ40 aggregation and toxicity.
- Lu N1, Yang Q2, Li J2, Tian R2, Peng YY3.
- European journal of pharmacology.Eur J Pharmacol.2015 Nov 15;767:160-4. doi: 10.1016/j.ejphar.2015.10.020. Epub 2015 Oct 16.
- It has been suggested that the aggregation and cytotoxicity of amyloid-β (Aβ) peptide with transition-metal ions in neuronal cells is involved in the development and progression of Alzheimer's disease (AD). As the most abundant protein in blood plasma and in cerebrospinal fluid, human serum albumi
- PMID 26463036
Japanese Journal
- Tau load is associated with apolipoprotein E genotype and the amount of amyloid beta protein, Abeta40, in sporadic and familial Alzheimer's disease
- THAKER U
- Neuropathol Appl Neurobiol 29, 35-44, 2003
- NAID 30014727765
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