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- 1. 自己免疫性肝炎の病因 pathogenesis of autoimmune hepatitis
English Journal
- A microfluidically perfused three dimensional human liver model.
- Rennert K1, Steinborn S1, Gröger M2, Ungerböck B3, Jank AM4, Ehgartner J5, Nietzsche S6, Dinger J7, Kiehntopf M8, Funke H4, Peters FT7, Lupp A9, Gärtner C3, Mayr T5, Bauer M10, Huber O11, Mosig AS12.
- Biomaterials.Biomaterials.2015 Dec;71:119-31. doi: 10.1016/j.biomaterials.2015.08.043. Epub 2015 Aug 25.
- Within the liver, non-parenchymal cells (NPCs) are critically involved in the regulation of hepatocyte polarization and maintenance of metabolic function. We here report the establishment of a liver organoid that integrates NPCs in a vascular layer composed of endothelial cells and tissue macrophage
- PMID 26322723
- Autoantibodies to asialoglycoprotein receptor (ASGPR) in patients with autoimmune liver diseases.
- Villalta D1, Mytilinaiou MG2, Elsner M3, Hentschel C3, Cuccato J3, Somma V3, Schierack P4, Roggenbuck D5, Bogdanos DP6.
- Clinica chimica acta; international journal of clinical chemistry.Clin Chim Acta.2015 Oct 23;450:1-5. doi: 10.1016/j.cca.2015.07.021. Epub 2015 Jul 26.
- BACKGROUND: The liver asialoglycoprotein receptor (ASGPR) is the only organ-specific autoantigenic target in autoimmune hepatitis (AIH) patients and corresponding autoantibodies (Abs) have been suggested aiding in the serology of autoimmune liver diseases (ALD).METHODS: A novel enzyme-linked immunos
- PMID 26220739
- Hepatitis B virus (HBV) receptors: Deficiency in tumor results in scant HBV infection and overexpression in peritumor leads to higher recurrence risk.
- Jing YY1, Liu WT1, Guo SW1, Ye F1, Fan QM1, Yu GF1, Yu DD1, Gao L1, Sun K1,2, Han ZP1, Li R1, Yang Y1, Zhao QD1, Wu MC1, Wang HY3, Wei LX1.
- Oncotarget.Oncotarget.2015 Oct 20. doi: 10.18632/oncotarget.5518. [Epub ahead of print]
- Hepatitis B virus (HBV) infection is a risk factor for hepatocarcinogenesis and recurrence. Here, we sought to characterize intratumoral and peritumoral expression of HBsAg and its specific receptors in HBsAg-positive hepatocellular carcinoma (HCC) patients and further examined their correlation wit
- PMID 26515593
Japanese Journal
- Receptor-Mediated Uptake of Human α1-Acid Glycoprotein into Liver Parenchymal Cells in Mice
- MATSUMOTO Kazuaki,NISHI Koji,KIKUCHI Mari,WATANABE Hiroshi,NAKAJOU Keisuke,KOMORI Hisakazu,KADOWAKI Daisuke,SUENAGA Ayaka,MARUYAMA Toru,OTAGIRI Masaki
- Drug metabolism and pharmacokinetics 25(1), 101-107, 2010-02-25
- NAID 10027582071
- 抗原捕捉免疫測定法による抗アシアロ糖タンパク質受容体抗体の検出 : 自己免疫性肝疾患における臨床的意義
- 森末 佳子
- 岡山醫學會雜誌 114(2), 159-165, 2002-09-30
- … In the development of autoimmune chronic acive hepatitis (AIH), the pathogenic relevance of antimmune responses against asialoglycoprotein recepter (ASGPR) has been implicated. … We have previously developed a capture enzyme-linked immunsorbent assay (ELISA) for detection of anti-ASGPR antibodies and found a high prevalence of anti-ASGPR antibodies in AIH and primary biliary cirrhosis (PBC). …
- NAID 10012336997
- Development of syngeneic monoclonal anti-idiotype antibodies to mouse monoclonal anti-asialoglycoprotein receptor antibody.
- Hirai Michio,Mizuno Motowo,Morisue Yoshiko,Yoshioka Masao,Shimada Morizou,Nasu Junichirou,Okada Hiroyuki,Shimomura Hiroyuki,Yamamoto Kazuhide,Tsuji Takao
- Acta Medica Okayama 56(3), 2002-06
- … The asialoglycoprotein receptor (ASGPR) is considered one of the target antigens in the pathogenesis of autoimmune chronic active hepatitis (AIH). … We previously developed a mouse monoclonal antibody (clone 8D7) which recognizes rat and human ASGPR. … In this study, to help investigate the anti-ASGPR antibody-anti-idiotype antibody network in patients with AIH, we developed a syngeneic mouse monoclonal Ab2 to the 8D7 anti-ASGPR antibody (Ab1). …
- NAID 120002312533
Related Links
- Asialoglycoprotein receptor (ASGPR) is a liver-specific autoantigen. A reliable test for anti-ASGPR antibodies has not been developed. Recent ELISA may allow efficient anti-ASGPR antibody testing. Anti-ASGPR ...
- hepatocyteはASGPR陽性vimentin陰性であり非実質細胞はvimentin陽性ASGPR陰性であります。そこで私は従来遠心方で行った肝細胞の分離をASGPR 認識高分子PVLAとvimentin認識高分子を用いることで試みました。 一方で近年 3) ...
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★リンクテーブル★
| リンク元 | 「asialoglycoprotein receptor」「アシアロ糖タンパク質受容体」「ASGP-R」「アシアロ糖蛋白質受容体」 |