副腎白質ジストロフィー遺伝子。ALD遺伝子
WordNet
- (genetics) a segment of DNA that is involved in producing a polypeptide chain; it can include regions preceding and following the coding DNA as well as introns between the exons; it is considered a unit of heredity; "genes were formerly called factors" (同)cistron, factor
- the 1st letter of the Roman alphabet (同)a
- the blood group whose red cells carry the A antigen (同)type_A, group A
- informal term for information; "give me the gen on your new line of computers"
PrepTutorEJDIC
- 遺伝子
- answer / ampere
- Alabama
UpToDate Contents
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English Journal
- CYP4F2 affects phenotypic outcome in adrenoleukodystrophy by modulating the clearance of very long-chain fatty acids.
- van Engen CE1, Ofman R1, Dijkstra IM1, van Goethem TJ1, Verheij E1, Varin J2, Vidaud M2, Wanders RJ1, Aubourg P3, Kemp S4, Barbier M5.
- Biochimica et biophysica acta.Biochim Biophys Acta.2016 Oct;1862(10):1861-70. doi: 10.1016/j.bbadis.2016.07.006. Epub 2016 Jul 15.
- X-linked adrenoleukodystrophy (ALD) is a severe neurodegenerative disorder caused by the accumulation of very long-chain fatty acids (VLCFA) due to mutations in the ABCD1 gene. The phenotypic spectrum ranges from a fatal cerebral demyelinating disease in childhood (cerebral ALD) to a progressive mye
- PMID 27425035
- Adrenoleukodystrophy - neuroendocrine pathogenesis and redefinition of natural history.
- Kemp S1,2, Huffnagel IC1,3, Linthorst GE4, Wanders RJ1,2, Engelen M1,3.
- Nature reviews. Endocrinology.Nat Rev Endocrinol.2016 Oct;12(10):606-15. doi: 10.1038/nrendo.2016.90. Epub 2016 Jun 17.
- X-Linked adrenoleukodystrophy (ALD) is a peroxisomal metabolic disorder with a highly complex clinical presentation. ALD is caused by mutations in the ABCD1 gene, which leads to the accumulation of very long-chain fatty acids in plasma and tissues. Virtually all men with ALD develop adrenal insuffic
- PMID 27312864
- Extracellular vesicles released by hepatocytes from gastric infusion model of ALD contain a miRNA barcode that can be detected in blood.
- Eguchi A1, Lazaro RG2, Wang J2, Kim J3, Povero D1, Willliams B4, Ho SB4,5, Stärkel P6, Schnabl B4,5, Ohno-Machado L3, Tsukamoto H2,7, Feldstein AE8.
- Hepatology (Baltimore, Md.).Hepatology.2016 Sep 17. doi: 10.1002/hep.28838. [Epub ahead of print]
- Extracellular vesicles (EVs) released during cell stress, or demise, can contain a barcode of the cell origin including specific microRNAs (miRNAs). Here we tested the hypothesis that during early alcoholic steatohepatitis (ASH) development, hepatocytes (HCs) release EVs with a miRNA signature that
- PMID 27639178
Japanese Journal
- Lorenzo's oil inhibits ELOVL1 and lowers the level of sphingomyelin with a saturated very long-chain fatty acid
- 遺伝性白質脳症とhereditary diffuse leukoencephalopathy with spheroids(HDLS)の分子病態
★リンクテーブル★
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- 英
- adrenoleukodystrophy gene
- 同
- ALD遺伝子 ALD gene
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