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English Journal
- Frataxin deficiency increases cyclooxygenase 2 and prostaglandins in cell and animal models of Friedreich's ataxia.
- Hayashi G1, Shen Y1, Pedersen TL2, Newman JW3, Pook M4, Cortopassi G5.
- Human molecular genetics.Hum Mol Genet.2014 Dec 20;23(25):6838-47. doi: 10.1093/hmg/ddu407. Epub 2014 Aug 7.
- An inherited deficiency of the mitochondrial protein frataxin causes Friedreich's ataxia (FRDA); the mechanism by which this deficiency triggers neuro- and cardio-degeneration is unclear. Microarrays of neural tissue of animal models of the disease showed decreases in antioxidant genes, and increase
- PMID 25104852
- Simultaneous quantification of leukotrienes and hydroxyeicosatetraenoic acids in cell culture medium using liquid chromatography/tandem mass spectrometry.
- Furugen A1, Yamaguchi H, Mano N.
- Biomedical chromatography : BMC.Biomed Chromatogr.2014 Dec 2. doi: 10.1002/bmc.3395. [Epub ahead of print]
- Leukotrienes (LTs) and hydroxyeicosatetraenoic acids (HETEs) are important bioactive lipid mediators that participate in various pathophysiological processes. To advance understanding of the mechanisms that regulate these mediators in physiological and pathological processes, an analytical method us
- PMID 25451304
- Effect of conjugated linoleic acid mixture supplemented daily after carcinogen application on linoleic and arachidonic acid metabolites in rat serum and induced tumours.
- Jelińska M1, Białek A2, Mojska H3, Gielecińska I4, Tokarz A5.
- Biochimica et biophysica acta.Biochim Biophys Acta.2014 Nov;1842(11):2230-6. doi: 10.1016/j.bbadis.2014.08.013. Epub 2014 Sep 6.
- Conjugated linoleic acid (CLA) is thought to exert anticarcinogenic, antiatherogenic, anti-inflammatory and weight loss effects. The impact on eicosanoid biosynthesis may be one of the mechanisms of its action. The aim of this study was to establish whether CLA mixture supplemented daily after admin
- PMID 25201082
Japanese Journal
- Decreased hepatic phosphorylated p38 mitogen-activated protein kinase contributes to attenuation of thioacetamide-induced hepatic necrosis in diet-induced obese mice
- Hypoxia suppresses Kv 2.1 channel expression through endogenous 15-hydroxyeicosatetraenoic acid in rat pulmonary artery
- The journal of physiological sciences : JPS 60(5), 373-381, 2010-09-01
- NAID 10027504673
- 373 アスピリン喘息患者における15-HETEの生成について(好中球/アスピリン不耐症, 第55回日本アレルギー学会秋季学術大会)
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- hydroxy-eicosatetraenoic acid