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1. 薬理ゲノム学の概要overview of pharmacogenomics [show details]
…interchangeably. Pharmacokinetics – Pharmacokinetics (PK) refers to how a drug moves through an individual body . A drug PK includes its absorption, distribution, metabolism, and elimination, all of which …
2. 成人における抗癌剤の投与dosing of anticancer agents in adults [show details]
…sensitivity, but also by the pharmacokinetic background of the patient (eg, cytochrome P450 enzymes, oral absorption, and environmental factors that influence pharmacokinetics), as well as adherence to the …
3. 栄養の吸収および吸収不良の機序mechanisms of nutrient absorption and malabsorption [show details]
…adversely impact on fat absorption will usually affect absorption of these vitamins in a parallel manner. The proximal half of the small intestine is the predominant site for the absorption of most vitamins …
4. 周術期に成人に静脈内投与するオピオイド鎮痛薬perioperative uses of intravenous opioids in adults [show details]
… excreted in the urine. Neither renal nor hepatic insufficiency affects fentanyl pharmacokinetics. The elimination half-life is three to six hours. Remifentanil is an ultrashort-acting fentanyl derivative …
5. 成人における薬物中毒への一般的アプローチgeneral approach to drug poisoning in adults [show details]
… of means. They may prevent absorption, bind and neutralize poisons directly, antagonize end-organ effects, or inhibit conversion to more toxic metabolites. The pharmacokinetics of both the toxin and the …