TNF receptor-associated factor

• TNF受容体関連因子、TNFレセプター関連因子

関

TRAF、tumor necrosis factor receptor-associated factor、tumor necrosis factor receptor-associated peptides and proteins

WordNet

1. having partial rights and privileges or subordinate status; "an associate member"; "an associate professor"
2. a person who joins with others in some activity or endeavor; "he had to consult his associate before continuing"
3. a person with subordinate membership in a society, institution, or commercial enterprise; "associates in the law firm bill at a lower rate than do partners"
4. any event that usually accompanies or is closely connected with another; "first was the lightning and then its thunderous associate"
5. make a logical or causal connection; "I cannot connect these two pieces of evidence in my mind"; "colligate these facts"; "I cannot relate these events at all" (同)tie_in, relate, link, colligate, link up, connect
6. be a contributing factor; "make things factor into a companys profitability"
7. any of the numbers (or symbols) that form a product when multiplied together
8. an independent variable in statistics
9. anything that contributes causally to a result; "a number of factors determined the outcome"
10. consider as relevant when making a decision; "You must factor in the recent developments" (同)factor in, factor out
11. resolve into factors; "a quantum computer can factor the number 15" (同)factor in, factor out
12. an event known to have happened or something known to have existed; "your fears have no basis in fact"; "how much of the story is fact and how much fiction is hard to tell"
13. a concept whose truth can be proved; "scientific hypotheses are not facts"
14. a piece of information about circumstances that exist or events that have occurred; "first you must collect all the facts of the case"
15. a statement or assertion of verified information about something that is the case or has happened; "he supported his argument with an impressive array of facts"
16. the 20th letter of the Roman alphabet (同)t
17. a cellular structure that is postulated to exist in order to mediate between a chemical agent that acts on nervous tissue and the physiological response

PrepTutorEJDIC

1. 〈人〉'を'(…の)『仲間に加える』,(…に)連合させる《+『名』〈人〉+『with』+『名』》 / (…と)…'を'結びつけて考える(起こす)《+『名』+『with』+『名』》 / (…と)『仲間になる』,交際する《+『with』+『名』》 / (…と)合体する,提携する《+『with』+『名』》 / 『仲間』,『同僚』;組合員 / 準会員 / 付属物;連想されるもの / 連合した;仲間の,同僚の / 補助の,準…
2. (…の)『要因』,(…を生み出す)要素《+『in』+『名』(do『ing』)》 / 囲数,約数 / 代理人,《おもに英》仲買人 / =factorize
3. 〈C〉『事実』,実際にある(あった)事 / 〈U〉真相,真実(truth) / 《the~》(法律用語で)犯行
4. tritiumの化学記号
5. =sense organ / 受信装置

UpToDate Contents

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• 1. 関節リウマチにおけるHLAおよびその他の感受性遺伝子 hla and other susceptibility genes in rheumatoid arthritis
• 2. エプスタインバーウイルス（EBウイルス）のウイルス学 virology of epstein barr virus
• 3. 原発性縦隔大細胞型B細胞リンパ腫 primary mediastinal large b cell lymphoma
• 4. Toll様受容体：疾患および治療における役割 toll like receptors roles in disease and therapy
• 5. 腫瘍壊死因子受容体-1関連周期性発熱症候群（TRAPS） tumor necrosis factor receptor 1 associated periodic syndrome traps

English Journal

• MicroRNA-146a-5p attenuates neuropathic pain via suppressing TRAF6 signaling in the spinal cord.

• Lu Y1, Cao DL2, Jiang BC2, Yang T2, Gao YJ3.
• Brain, behavior, and immunity.Brain Behav Immun.2015 Oct;49:119-29. doi: 10.1016/j.bbi.2015.04.018. Epub 2015 May 5.
• Glia-mediated neuroinflammation plays an important role in the pathogenesis of neuropathic pain. Our recent study demonstrated that TNF receptor associated factor-6 (TRAF6) is expressed in spinal astrocytes and contributes to the maintenance of spinal nerve ligation (SNL)-induced neuropathic pain. M
• PMID 25957028

• TGF-β1 inhibits the production of IFN in response to CpG DNA via ubiquitination of TNF receptor-associated factor (TRAF) 6.

• Naiki Y1, Komatsu T2, Koide N2, Dagvadorj J3, Yoshida T2, Arditi M4, Yokochi T2.
• Innate immunity.Innate Immun.2015 Oct;21(7):770-7. doi: 10.1177/1753425915596844. Epub 2015 Jul 29.
• The effect of TGF-β1 on CpG DNA-induced type I IFN production was examined by reconstituting a series of signaling molecules in TLR 3 signaling. TGF-β1 inhibited CpG DNA-induced IFN-α4 productivity in HeLa cells. Transfection of IFN regulatory factor (IRF)7 but not TNF receptor-associated factor
• PMID 26224488

• HPV Type 16 Infection Switches Keratinocytes from Apoptotic to Proliferative Fate under TWEAK/Fn14 Interaction.

• Cheng H1,2, Zhan N3, Ding D4, Liu X5, Zou X6, Li K7, Xia Y1.
• The Journal of investigative dermatology.J Invest Dermatol.2015 Oct;135(10):2427-36. doi: 10.1038/jid.2015.201. Epub 2015 May 27.
• Previously, tumor necrosis factor (TNF)-like weak inducer of apoptosis (TWEAK) had been known to be an inducer of apoptosis of keratinocytes by engaging the Fn14 receptor. However, the high-risk human papillomavirus (HPV) infection confers a proliferation advantage on keratinocytes that may conseque
• PMID 26016896

Japanese Journal

• ユビキチン鎖とNF-κB活性化

• 臨床免疫・アレルギー科 = Clinical immunology & allergology 68(5), 569-575, 2017-11
• NAID 40021382537

• LS1-2　自己炎症疾患の診断と治療における最新の知見

• 日本臨床免疫学会会誌 40(4), 286a-286a, 2017
• NAID 130006219400

• Ubc13 haploinsufficiency protects against age-related insulin resistance and high-fat diet-induced obesity

• Scientific Reports 6, 2016-10-31
• NAID 120005867104

Related Links

• Tumor necrosis factor receptor-associated factors (TRAFs).

1. Oncogene. 2001 Oct 1;20(44):6482-91. Tumor necrosis factor receptor-associated factors (TRAFs). Bradley JR(1), Pober JS. Author information: (1)Department of Medicine, University of Cambridge School of ...

• TRAF1 TNF receptor associated factor 1 [ (human)]

The protein encoded by this gene is a member of the TNF receptor (TNFR) associated factor (TRAF) protein family. TRAF proteins associate with, and mediate the signal transduction from various receptors of the TNFR ...

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★リンクテーブル★

リンク元	「tumor necrosis factor receptor-associated factor」「TNF受容体関連因子」「TRAF」「TNFレセプター関連因子」
拡張検索	「TNF receptor-associated factor 3」「TNF receptor-associated factor 2」「TNF receptor-associated factor 4」「TNF receptor-associated factor 5」
関連記事	「associate」「fact」「TNF receptor」「factor」「T」

「tumor necrosis factor receptor-associated factor」

　　[★]

• 腫瘍壊死因子受容体関連因子、TNF受容体関連因子

関

TNF receptor-associated factor、TRAF、tumor necrosis factor receptor-associated peptides and proteins

「TNF受容体関連因子」

　　[★]

英

tumor necrosis factor receptor-associated factor、TNF receptor-associated factor、TRAF

関

腫瘍壊死因子受容体関連因子、TNFレセプター関連因子

「TRAF」

　　[★]

• TNF受容体関連因子

関

TNF receptor-associated factor、tumor necrosis factor receptor-associated factor

「TNFレセプター関連因子」

　　[★]

英

TNF receptor-associated factor

関

腫瘍壊死因子受容体関連因子、TNF受容体関連因子

「TNF receptor-associated factor 3」

　　[★]

TNF受容体関連因子3

関

TRAF-3、TRAF3

「TNF receptor-associated factor 2」

　　[★]

TNF受容体関連因子2

関

TRAF2

「TNF receptor-associated factor 4」

　　[★]

TNF受容体関連因子4

関

TRAF4

「TNF receptor-associated factor 5」

　　[★]

TNF受容体関連因子5

関

TRAF5

「associate」

　　[★]

• vt.

• 結合する、連合させる。連想によって結びつける。(人を)仲間/友達などとしての関係に置く。(化)会合させる

• vi.

• 仲間/友人などとして交際する(with)。一つにまとめる、連合する

• n.

• 仕事仲間、提携者、同僚。友人、朋友。準会員。従業員、社員
• 密接な蒸す偽付きのある物、付随する物、つきもの。準国家
• 連想によって心に浮かぶ言葉/思い、連想物

• adj.

• 仲間の、同僚の。製紙機械員に次ぐ資格の
• 付随する、連想される

関

accompany、association、associative、attach、bearing、bind、binding、bond、bonding、coassemble、colleague、combine、conjoin、conjugate、conjugation、conjunction、connect、connection、correlate、correlation、couple、dock、engage、engagement、federation、implication、join、joint、ligate、link、linkage、peer、pertinent、reference、relate、relation、relationship、relative、relevance、relevant、symphysial、union

　 　 　 　 　 　

「fact」

　　[★]

• n.

• 事実、現状、実際、実態

関

actual、actually、in fact、in practice、indeed、practically

　 　 　 　 　

「TNF receptor」

　　[★]

• 腫瘍壊死因子受容体、腫瘍壊死因子レセプター、TNF受容体、TNFレセプター

関

TNFR、tumor necrosis factor receptor

「factor」

　　[★]

• n.

• 因子、要因、要素、ファクター

関

element、elementary、factorial、parameter

　 　 　 　 　 　 　

「T」

　　[★]

• T波 T wave
• チミン thymine
• ツイスト数
• スレオニントレオニン threonine