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English Journal
- New insights about the posttranscriptional mechanisms triggered by iodide excess on sodium/iodide symporter (NIS) expression in PCCl3 cells.
- Serrano-Nascimento C, Calil-Silveira J, Goulart-Silva F, Nunes MT.SourceDepartment of Physiology and Biophysics, Institute of Biomedical Sciences, University of São Paulo, 05508-000 São Paulo, SP, Brazil.
- Molecular and cellular endocrinology.Mol Cell Endocrinol.2012 Feb 26;349(2):154-61. Epub 2011 Oct 1.
- Iodide excess acutely downregulates NIS mRNA expression, as already demonstrated. PCCl3 cells treated or not with NaI, NaI+NaClO(4) or NaI+Methimazole, for 30min to 24h, were used to further explore how iodide reduces NIS gene expression. NIS mRNA expression was evaluated by Real-Time PCR; its poly(
- PMID 22001309
- Hypothyroidism reduces glutamate-synaptic release by ouabain depolarization in rat CA3-hippocampal region.
- Sánchez-Huerta KB, Montes S, Pérez-Severiano F, Alva-Sánchez C, Ríos C, Pacheco-Rosado J.SourceDepartamento de Fisiología "Mauricio Russek," Escuela Nacional de Ciencias Biológicas, IPN, México D.F., México.
- Journal of neuroscience research.J Neurosci Res.2011 Dec 20. doi: 10.1002/jnr.22806. [Epub ahead of print]
- Thyroid hormones modulate the physiology of the hippocampus in humans, where glutamate plays an important role as neurotransmitter. The aim of this work was to study the effect of hypothyroidism on hippocampal glutamate extracellular levels, release, uptake, and synthesis. The effects of PDC (a glut
- PMID 22184033
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- Tapazole [tap´ah-zōl] trademark for a preparation of methimazole, used as a thyroid inhibitor. methimazole Apo-Methimazole (CA), Tapazole Pharmacologic class: Thiomidazole derivative Therapeutic class: Antithyroid drug Pregnancy ...
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