小胞体でタンパク質に付与されるオリゴ糖
アスパラギンを含む特定の配列が認識され、アスパラギンの-NH₂にオリゴ糖が付与される
ゴルジ装置で修飾を受ける。

UpToDate Contents

全文を閲覧するには購読必要です。 To read the full text you will need to subscribe.

1. 髄膜炎菌の微生物学および病理生物学microbiology and pathobiology of neisseria meningitidis [show details]
…chemical structures of the oligosaccharide portion of all 12 LOS serotypes have been elucidated. Many of the biosynthesis genes necessary for the production of the oligosaccharide portion of the LOS have …
2. B群レンサ球菌感染症予防のための予防接種vaccines for the prevention of group b streptococcal disease [show details]
…serotype specificity for GBS. With only two exceptions, all GBS CPS are composed of 150 or more oligosaccharide repeating units of galactose, glucose, N-acetylglucosamine, and N-acetylneuraminic acid. Type …
3. 赤血球細胞膜：構造、機構、動態red blood cell membrane structure organization and dynamics [show details]
…this domain may bind carbonic anhydrase. Band 3 also contains a single N-glycosidically linked oligosaccharide that carries several blood groups including I and Diego . Aquaporin-1 belongs to a family…
4. 小児における急性中耳炎：再発予防acute otitis media in children prevention of recurrence [show details]
…prevent AOM . We do not suggest the administration of oligosaccharides to prevent recurrent AOM in children. Administration of oligosaccharides may be helpful in the prevention of infection by inhibiting …
5. B群レンサ球菌：病原性因子および発症機序group b streptococcus virulence factors and pathogenic mechanisms [show details]
…specificity to GBS . These complex carbohydrates are composed of approximately 150 repeating oligosaccharide subunits . The 10 capsular serotypes (Ia, Ib, II, III, IV, V, VI, VII, VIII and IX) currently …

English Journal

Asn-linked oligosaccharide chain of a crenarchaeon, Pyrobaculum calidifontis, is reminiscent of the eukaryotic high-mannose-type glycan.

Fujinami D, Taguchi Y, Kohda D.
Glycobiology. 2017 May;().
Pyrobaculum calidifontis is a hyperthermophilic archaeon that belongs to the phylum Crenarchaeota. In contrast to the phylum Euryarchaeota, only the N-glycan structure of the genus Sulfolobus is known in Crenarchaeota. Here, we enriched glycoproteins from cultured P. calidifontis cells, by ConA lect
PMID 28510654

Investigating the relationship between temperature, conformation and calcium binding in heparin model oligosaccharides.

Hughes A, Meneghetti M, Huang TY, Hung SC, Elli S, Guerrini M, Rudd T, Lima M, Yates E.
Carbohydrate research. 2017 Jan;438()58-64.
Glycosaminoglycans such as heparan sulfate (HS) are major components of the cell surface and extracellular matrix (ECM) of all multicellular animals, connecting cells to each other as well as to their environment. The ECM must, therefore, both sense and accommodate changes to external conditions. He
PMID 27987423

Characterisation of alpha3beta1 and alpha(v)beta3 integrin N-oligosaccharides in metastatic melanoma WM9 and WM239 cell lines.

Kremser ME, Przybyło M, Hoja-Łukowicz D, Pocheć E, Amoresano A, Carpentieri A, Bubka M, Lityńska A.
Biochimica et biophysica acta. 2008 Dec;1780(12)1421-31.
It is well documented that glycan synthesis is altered in some pathological processes, including cancer. The most frequently observed alterations during tumourigenesis are extensive expression of beta1,6-branched complex type N-glycans, the presence of poly-N-acetyllactosamine structures, and high s
PMID 18755246