ポエムス症候群
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参考
- 1. 単クローン抗体を伴う末梢神経炎 （クロウ・フカセ症候群、POEMS症候群） - 難病情報センター
- <click2in>http://www.nanbyou.or.jp/entry/241</click2in>
- 2．[PDF]診断基準など
- <click2in>http://www.celltherapytransplantation.com/520-3_520.pdf</click2in>
- 3. 疫学研究としての診断基準
- <click2in>http://www.m.chiba-u.ac.jp/class/neurol/kenkyu/ishisyudou/crow-fukase/ishi/sindan.html</click2in>
腎障害を伴うPOEMS症候群
- 検索ワード「POEMS syndrome glomerulonephritis」
- Serial renal biopsy findings in a case of POEMS syndrome with recurrent acute renal failure.
- Marked recovery of severe renal lesions in POEMS syndrome with high-dose melphalan therapy supported by autologous blood stem cell transplantation.
- http://www.ncbi.nlm.nih.gov/pubmed/16564945
- Although not included in the acronym, renal lesions also are characteristic of this disease and sometimes require dialysis therapy.
- 腎障害も良く合併するんだって
- POEMS syndrome: definitions and long-term outcome.
- http://www.ncbi.nlm.nih.gov/pubmed/12456500
- The POEMS syndrome (coined to refer to polyneuropathy, organomegaly, endocrinopathy, M protein, and skin changes) remains poorly understood. Ambiguity exists over the features necessary to establish the diagnosis, treatment efficacy, and prognosis. We identified 99 patients with POEMS syndrome. Minimal criteria were a sensorimotor peripheral neuropathy and evidence of a monoclonal plasmaproliferative disorder. To distinguish POEMS from neuropathy associated with monoclonal gammopathy of undetermined significance, additional criteria were included: a bone lesion, Castleman disease, organomegaly (or lymphadenopathy), endocrinopathy, edema (peripheral edema, ascites, or effusions), and skin changes.
- Successful stabilisation of nephropathy in a patient with POEMS (polyneuropathy, organomegaly, endocrinopathy, M-band, skin changes) syndrome on treatment with mycophenolate and steroids: a case report
- http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2848064/
- Nakamoto et al. [7] reviewed 52 cases of Japanese patients with nephropathy. All patients manifested four or all of the five signs of POEMS. Polyneuropathy was present in all but one patient. A majority of cases had monoclonal protein in blood (either IgA- or IgG-) although 10 demonstrated a polyclonal hypergammaglobulinaemia, but in these, four other signs of POEMS supported the diagnosis.
- Nakamoto et al. [7] -> http://www.ncbi.nlm.nih.gov/pubmed/10528660
- Nakamoto et al. [7] reviewed 52 cases of Japanese patients with nephropathy. All patients manifested four or all of the five signs of POEMS. Polyneuropathy was present in all but one patient. A majority of cases had monoclonal protein in blood (either IgA- or IgG-) although 10 demonstrated a polyclonal hypergammaglobulinaemia, but in these, four other signs of POEMS supported the diagnosis.