カスパーゼ
ヒトICEプロテアーゼスーパーファミリー
| Family | Caspase | Other Name | Recognition | Target (Truncation site) |
| caspase-1 | caspase-1 | ICE | WEHD | pro IL-1β (FEAD/G, YVHD/A), procaspase-3, procaspase-4 |
| caspase-4 | ICErel-II, TX, ICH-2 | |||
| caspase-5 | ICErel-III, TY | |||
| caspase-2 | caspase-2 | ICH-1 | DEHD | PARP (DEVD/G) |
| caspase-9 | ICE-LAP6, Mch6 | LEHD | PARP, procaspase-3 | |
| caspase-3 | caspase-3 | CPP32, Yama | DEVD | PARP, SREBP (DEPD/S), U1snRNP (DGPD/G), lamin B, D4-GDI (DELD/S), DNA-PK (DEVD/N), DFF (DETD/S, DAVD/T), actin (ELPD/G) ?, PKCδ (DMQD/N) ?]] |
| caspase-7 | Mch3, ICE-LAP3, CMH-1 | DEVD | PARP, procaspase-6 | |
| caspase-6 | Mch2 | VEHD | lamin A (VEID/N)]] | |
| caspase-8 | FLICE, MACH, Mch5 | LETD | procaspase-3, Bid | |
| caspase-10 | Mch4 | LEXD | ||
| caspase-11 | Ich3 |