wedged hepatic venous pressure

閉塞肝静脈圧

WordNet

1. the force applied to a unit area of surface; measured in pascals (SI unit) or in dynes (cgs unit); "the compressed gas exerts an increased pressure" (同)pressure level, force per unit area
2. an oppressive condition of physical or mental or social or economic distress
3. the somatic sensation that results from applying force to an area of skin; "the sensitivity of his skin to pressure and temperature was normal" (同)pressure_sensation
4. a force that compels; "the public brought pressure to bear on the government"
5. squeeze like a wedge into a tight space; "I squeezed myself into the corner" (同)squeeze, force
6. any shape that is triangular in cross section (同)wedge_shape, cuneus
7. (golf) an iron with considerable loft and a broad sole
8. something solid that is usable as an inclined plane (shaped like a V) that can be pushed between two things to separate them
9. of or contained in or performing the function of the veins; "venous inflammation"; "venous blood as contrasted with arterial blood"; "venous circulation"
10. pertaining to or affecting the liver; "hepatic ducts"; "hepatic cirrhosis"

PrepTutorEJDIC

1. 〈U〉『押すこと』,『押しつけること』,圧搾,圧縮;〈C〉〈U〉『圧力』,圧力の強さ / 〈U〉『圧迫』,『強制』 / 〈U〉(不快な)圧迫感 / 〈C〉〈U〉(精神的な)重荷,苦脳;(時間・金銭的)切迫 / 〈U〉多忙,あわただしさ / 《おもに米》…‘に'圧力をかける,強制する(《英》pressurise)
2. (特に,木製の)『くさび』 / 『くさび形の物』;くさびのような働きをするもの / (ゴルフの)ウェッジ(頭部がくさび形の短いアイアンクラブ) / …‘に'くさびを打ち込む / (…に)…‘を'無理に押し込んで動けないようにする《+名+in(into)+名》 / (…に)無理に割り込む,押し入る《+into+名》
3. 静脈[血]の / 葉脈の多い
4. 肝臓の;肝臓にきく,肝臓のような色の
5. くぎ付けになった

Wikipedia preview

出典(authority):フリー百科事典『ウィキペディア（Wikipedia）』「2015/10/20 17:49:32」(JST)

wiki en

[Wiki en表示]

Portal venous pressure is the blood pressure in the hepatic portal vein, and is normally between 5-10 mmHg. Raised portal venous pressure is termed portal hypertension, and has numerous sequelae such as ascites and hepatic encephalopathy.

Wedged hepatic venous pressure (WHVP)

WHVP is used to estimate the portal venous pressure by reflecting not the actual hepatic portal vein pressure but the hepatic sinusoidal pressure. It is determined by wedging a catheter in a hepatic vein, to occlude it, and then measuring the pressure of proximal static blood (which is reflective of pressure in the sinusoids). WHVP in fact slightly underestimates portal pressure due to sinusoidal equilibration in patients without cirrhosis, but the difference between the two is clinically insignificant. In patients with cirrhotic livers intersinusoidal communication is disrupted such that sinusoidal pressure equilibrium cannot be maintained, and so WHVP becomes a far more accurate measure of portal venous pressure.

Hepatic venous pressure gradient (HVPG)

HVPG is a clinical measurement of the pressure gradient between the WHVP and the free hepatic venous pressures, and thus is an estimate of the pressure gradient between the portal vein and the inferior vena cava. An HVPG of ≥10 mmHg defines clinically significant portal hypertension, and if the measurement exceeds 12 mmHg variceal haemorrhaging may occur. While not widely performed, its assessment in people with chronic liver disease is recommended to monitor response to treatment.

References

External links

• Portal Pressure at the US National Library of Medicine Medical Subject Headings (MeSH)

UpToDate Contents

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• 1. 成人における門脈圧亢進症 portal hypertension in adults
• 2. 非肝硬変性門脈圧亢進症 noncirrhotic portal hypertension
• 3. 肝硬変患者における静脈瘤出血の予測 prediction of variceal hemorrhage in patients with cirrhosis
• 4. 肝硬変患者における静脈瘤出血に対する一次予防および静脈瘤形成予防 primary and pre primary prophylaxis against variceal hemorrhage in patients with cirrhosis
• 5. 造血細胞移植後の肝類洞閉塞症候群（静脈閉塞性疾患）の診断 diagnosis of hepatic sinusoidal obstruction syndrome veno occlusive disease following hematopoietic cell transplantation

English Journal

• The prognostic value of HVPG in patients with cirrhosis is highly dependent on the accuracy of the technique.

• Silva-Junior G1, Baiges A1, Turon F1, Torres F2,3, Hernández-Gea V1,4, Bosch J1,4, García-Pagán JC1,4.
• Hepatology (Baltimore, Md.).Hepatology.2015 Aug 3. doi: 10.1002/hep.28031. [Epub ahead of print]
• BACKGROUND AND AIM: Hepatic venous pressure gradient (HVPG), the difference between wedged (WHVP) and free hepatic vein pressure (FHVP), predicts survival in patients with cirrhosis. It has been suggested the use of inferior vena cava (IVC) value instead of FHVP to calculate HVPG when the difference
• PMID 26238376

• Impact of splenic circulation: non-invasive microbubble-based assessment of portal hemodynamics.

• Shimada T1, Maruyama H, Kondo T, Sekimoto T, Takahashi M, Yokosuka O.
• European radiology.Eur Radiol.2015 Mar;25(3):812-20. doi: 10.1007/s00330-014-3476-3. Epub 2014 Nov 1.
• OBJECTIVE: The objective was to examine the effect of splenic circulation using a microbubble agent to assess the severity of portal hypertension.METHODS: This prospective study consisted of 91 subjects (63.0 ± 12.6 years, 30-86; 60 males, 31 females), 62 cirrhosis and 29 controls, who underwen
• PMID 25361826

• Saline-enhanced ultrasonography: prediction of X-ray appearance of hepatic venography in patients with cirrhosis.

• Maruyama H1, Kiyono S, Kamesaki H, Kondo T, Sekimoto T, Yokosuka O.
• Scandinavian journal of gastroenterology.Scand J Gastroenterol.2014 May;49(5):625-31. doi: 10.3109/00365521.2014.887766. Epub 2014 Mar 20.
• OBJECTIVE: To examine the efficacy of saline-enhanced ultrasound (US) in predicting the X-ray appearance of hepatic venography.MATERIALS AND METHODS: This prospective study consisted of 50 cirrhosis patients (31 males and 19 females; mean age, 64.2±11.1 years). US patterns in the liver, after injec
• PMID 24646346

Japanese Journal

• Three Minimally Invasive Methods of Measuring of Portal Vein Pressure in Healthy Dogs

• Ｔｈｅ　Ｊｏｕｒｎａｌ　ｏｆ　Ｖｅｔｅｒｉｎａｒｙ　Ｍｅｄｉｃａｌ　Ｓｃｉｅｎｃｅ 74(10), 1299-1302, 2012
• NAID 130001879820

• ステロイド使用により食道静脈瘤の消失を認めた特発性門脈圧亢進症合併全身性エリテマトーデスの1例

• 日本臨床免疫学会会誌 = Japanese journal of clinical immunology 27(1), 40-47, 2004-02-29
• NAID 10012927123

• 門脈圧亢進症における部分的脾塞栓術 (PSE) と門脈血流

• 日門亢会誌 7(4), 207-212, 2001
• NAID 130004635833

Related Links

• Measurement of hepatic venous pressure gradient revisited ...

Introduction Hepatic venous wedge pressure (HVWP) is a dynamic variable reflecting the hepatic sinusoidal pressure and therefore, indirectly, the portal pressure.[1] It is used to calculate the hepatic venous pressure ...

• Wedged hepatic vein pressure | definition of wedged hepatic ...

pressure (P) [presh´ur] force per unit area. arterial pressure (arterial blood pressure) blood pressure (def. 2). atmospheric pressure the pressure exerted by the atmosphere, usually considered as the downward pressure of air onto a ...

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★リンクテーブル★

リンク元	「閉塞肝静脈圧」
関連記事	「hepatic」「wedge」「venous」「pressure」

「閉塞肝静脈圧」

　　[★]

英

wedged hepatic venous pressure WHVP, hepatic venous wedge pressure

同

閉塞性肝静脈圧

関

特発性門脈圧亢進症、門脈圧亢進症

[show details]

閉塞性肝静脈圧 : 16 件
閉塞肝静脈圧 : 100 件

概念

• 肝静脈が下大静脈に流入する部位で閉塞させたときに測定される圧。
• カテーテルを下大静脈から肝静脈に嵌入させて末端圧を測定する。
• 類洞における血流が完全に停止するのに必要な圧にほぼ比例する。(参考3)
• 肝静脈末端圧。
• 正常では門脈圧 PVP　≒　類洞内圧　≒　閉塞肝静脈圧 WHVP

病態との関連

• 類洞性・後類洞性(肝硬変)、肝後性(Budd-Chiari症候群、うっ血性不全)により上昇。(1)
• 肝後性、肝外肝静脈、脾内圧↑、WHVP↑、腹水＋＋
• 特発性門脈圧亢進症：門脈圧(PVP)　≒　類洞内圧　≠　閉塞肝静脈圧 WHVP

正常値

• 70-80mm/H2O

参考

• (1)

http://blog.livedoor.jp/idiacorp/archives/1605441.html

• 2. suuchan.net

http://suuchan.net/note/Chapter-040803.html

• 3.

http://blog.livedoor.jp/idiacorp/archives/1605441.html

「hepatic」

　　[★]

• adj.

• 肝臓の、肝性の、肝の

関

hepato、hepatogenic、liver

　 　

「wedge」

　　[★]

• n.

• くさび、楔、矢
• 間を裂くもの、分裂の因

• vt.

　 　 　 　 　

「venous」

　　[★]

• adj.

• 静脈性の、静脈の

関

vein、vena

　 　

「pressure」

　　[★]

• n.

• 圧力