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  • Aromatase Imaging with [N-Methyl-11C]Vorozole PET in Healthy Men and Women.
  • Biegon A1, Alexoff DL2, Kim SW3, Logan J4, Pareto D5, Schlyer D2, Wang GJ3, Fowler JS6.
  • Journal of nuclear medicine : official publication, Society of Nuclear Medicine.J Nucl Med.2015 Apr;56(4):580-5. doi: 10.2967/jnumed.114.150383. Epub 2015 Feb 19.
  • Aromatase, the last and obligatory enzyme catalyzing estrogen biosynthesis from androgenic precursors, can be labeled in vivo with (11)C-vorozole. Aromatase inhibitors are widely used in breast cancer and other endocrine conditions. The present study aimed to provide baseline information defining ar
  • PMID 25698781
  • Autoradiography screening of potential positron emission tomography tracers for asymptomatic abdominal aortic aneurysms.
  • Tegler G1, Estrada S, Hall H, Wanhainen A, Björck M, Sörensen J, Antoni G.
  • Upsala journal of medical sciences.Ups J Med Sci.2014 Aug;119(3):229-35. doi: 10.3109/03009734.2014.894157. Epub 2014 Feb 21.
  • OBJECTIVE: The aetiology and early pathophysiological mechanisms of aortic aneurysm formation are still unknown and challenging to study in vivo. Positron emission tomography (PET) is a potentially valuable instrument for non-invasive in vivo pathophysiological studies. No specific tracer to identif
  • PMID 24555564
  • 11C-cetrozole: an improved C-11C-methylated PET probe for aromatase imaging in the brain.
  • Takahashi K1, Hosoya T, Onoe K, Doi H, Nagata H, Hiramatsu T, Li XL, Watanabe Y, Wada Y, Takashima T, Suzuki M, Onoe H, Watanabe Y.
  • Journal of nuclear medicine : official publication, Society of Nuclear Medicine.J Nucl Med.2014 May;55(5):852-7. doi: 10.2967/jnumed.113.131474. Epub 2014 Mar 27.
  • Aromatase (an enzyme that converts androgens to estrogens) in the brain is involved in neuroprotection, synaptic plasticity, and regulation of sexual and emotional behaviors. To investigate the physiologic and pathologic importance of aromatase in the brain, including in humans, we here report the d
  • PMID 24676756


  • ラットDMBA誘発乳癌における新規aromatase阻害剤vorozoleの抗腫瘍効果とIGF-1抑制作用
  • 菅又 徳孝,飯野 佑一,鯉淵 幸生,安東 立正,松本 広志,前村 道生,武井 寛幸,堀口 淳,横江 隆夫,森下 靖雄
  • 日本外科学会雑誌 99(臨時増刊), 339, 1998-03-10
  • NAID 110003952557