voltage-dependent Ca2+ channel

出典: meddic

Cav channelVDCCvoltage-dependent calcium channelvoltage-gated Ca2+ channelvoltage-gated calcium channel

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英文文献

  • Asn-Linked Glycosylation Contributes to Surface Expression and Voltage-Dependent Gating of Cav1.2 Ca2+ Channel.
  • Park HJ1, Min SH1, Won YJ1, Lee JH1.
  • Journal of microbiology and biotechnology.J Microbiol Biotechnol.2015 Aug 28;25(8):1371-9. doi: 10.4014/jmb.1501.01066.
  • The Cav1.2 Ca2+ channel is essential for cardiac and smooth muscle contractility and many physiological functions. We mutated single, double, and quadruple sites of the four potential Asn (N)-glycosylation sites in the rabbit Cav1.2 into Gln (Q) to explore the effects of Nglycosylation. When a singl
  • PMID 25824433
  • Voltage-dependent BK and Hv1 channels expressed in non-excitable tissues: New therapeutics opportunities as targets in human diseases.
  • Morera FJ1, Saravia J2, Pontigo JP3, Vargas-Chacoff L3, Contreras GF4, Pupo A4, Lorenzo Y4, Castillo K4, Tilegenova C5, Cuello LG6, Gonzalez C7.
  • Pharmacological research : the official journal of the Italian Pharmacological Society.Pharmacol Res.2015 Aug 21. pii: S1043-6618(15)00179-6. doi: 10.1016/j.phrs.2015.08.011. [Epub ahead of print]
  • Voltage-gated ion channels are the molecular determinants of cellular excitability. This group of ion channels is one of the most important pharmacological targets in excitable tissues such as nervous system, cardiac and skeletal muscle. Moreover, voltage-gated ion channels are expressed in non-exci
  • PMID 26305431
  • Functional coupling between sodium-activated potassium channels and voltage-dependent persistent sodium currents in cricket Kenyon cells.
  • Takahashi I, Yoshino M1.
  • Journal of neurophysiology.J Neurophysiol.2015 Aug 12:jn.00087.2015. doi: 10.1152/jn.00087.2015. [Epub ahead of print]
  • In this study, we examined the functional coupling between Na+-activated potassium (KNa) channels and Na+-influx through voltage-dependent Na+ channels in Kenyon cells isolated from the mushroom body of the cricket. Single channel activity of KNa channels was recorded with the cell-attached patch co
  • PMID 26269549

和文文献

  • Sucralose, an activator of the glucose-sensing receptor, increases ATP by calcium-dependent and -independent mechanisms
  • Synthesis, Evaluation of Pharmacological Activity, and Molecular Docking of 1,4-Dihydropyridines as Calcium Antagonists
  • Involvement of TRPM2 and L-type Ca²⁺ channels in Ca²⁺ entry and cell death induced by hydrogen peroxide in rat β-cell line RIN-5F

関連リンク

1. Graefes Arch Clin Exp Ophthalmol. 2008 May;246(5):685-92. doi: 10.1007/s00417-008-0778-7. Epub 2008 Feb 13. Expression profile of voltage-dependent Ca2+ channel subunits in the human retinal pigment epithelium. Wimmers S ...
Frog taste cells were hyperpolarized by injecting an inward current pulse, and regenerative anode-break potentials were observed at the termination of the current pulse. The results obtained are as follows. 1) The magnitude of the ...

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★リンクテーブル★
先読み電位依存性カルシウムチャネル」「voltage-gated calcium channel」「voltage-gated Ca2+ channel」「VDCC」「Cav channel
関連記事channel」「dependent」「C」「voltage」「channels

電位依存性カルシウムチャネル」

  [★]

voltage-dependent calcium channel, VDCC
電位関門型カルシウムチャネル voltage-gated calcium channel VGCC電位作動型カルシウムチャネル voltage-operated calcium channel VOCC, 電位依存性Ca2+チャネル
イオンチャネル電位依存性イオンチャネル
[show details]



  • α1サブユニット単独でチャネルを形成できる (SP.93)
  • β, γ, α2/δの3種類の副サブユニットはチャネルの機能を修飾する

電位依存性カルシウムチャネルの分類 (SP.93)

α1サブユニット遺伝子 発現組織 阻害薬 閾電位 コンダクタンス
L型 Cav 1.1 骨格筋 ジヒドロピリジンベラパミルジルチアゼム
Cav 1.2 心臓、神経系、内分泌系
Cav 1.3 神経系、内分泌系、内有毛細胞
Cav 1.4 視細胞
P/Q型 Cav 2.1 神経系  
N型 Cav 2.2  
R型 Cav 2.3  
T型 Cav 3.1 神経系、心臓、平滑筋、腎臓、内分泌系  
Cav 3.2  
Cav 3.3  


voltage-gated calcium channel」

  [★]

voltage-dependent Ca2+ channelvoltage-dependent calcium channelvoltage-gated Ca2+ channel


voltage-gated Ca2+ channel」

  [★]

voltage-dependent Ca2+ channelvoltage-dependent calcium channelvoltage-gated calcium channel

VDCC」

  [★]

calcium channelCav channelvoltage-dependent Ca2+ channelvoltage-dependent calcium channel

Cav channel」

  [★]

VDCCvoltage-dependent Ca2+ channelvoltage-dependent calcium channel


channel」

  [★]

  • n.
  • 川床、川底。水路、河道
  • 海峡
  • 水管、導管
  • 経路、ルート。道筋、方向
ion channelionic channel

WordNet   license wordnet

「direct the flow of; "channel information towards a broad audience"」
canalize, canalise

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「a television station and its programs; "a satellite TV channel"; "surfing through the channels"; "they offer more than one hundred channels"」
television channel, TV channel

WordNet   license wordnet

「a passage for water (or other fluids) to flow through; "the fields were crossed with irrigation channels"; "gutters carried off the rainwater into a series of channels under the street"」

WordNet   license wordnet

「(often plural) a means of communication or access; "it must go through official channels"; "lines of communication were set up between the two firms"」
communication channel, line

WordNet   license wordnet

「a path over which electrical signals can pass; "a channel is typically what you rent from a telephone company"」
transmission channel

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「a deep and relatively narrow body of water (as in a river or a harbor or a strait linking two larger bodies) that allows the best passage for vessels; "the ship went aground in the channel"」

PrepTutorEJDIC   license prepejdic

「〈C〉『水路』(川・湾・運河の船の通行ができる深い部分) / 〈U〉河床・川底 / 〈C〉『海峡』 / 〈C〉みぞ(groove),(道路の)水渠(すいきょ) / 《複数形で》(運搬・伝達の)正式の経路(手続き);(一般に)経路 / 〈C〉(テレビ・ラジオの)チャンネル / …‘に'水路を開く / …‘に'みぞを堀る / …'を'伝える,流す」

dependent」

  [★]

  • adj.
  • 依存性の、依存的な、依存型の、依存の
dependdependencedependencydependently

WordNet   license wordnet

「relying on or requiring a person or thing for support, supply, or what is needed; "dependent children"; "dependent on moisture"」

PrepTutorEJDIC   license prepejdic

「『頼っている』,依存している,従属している / 扶養される人(家族)」

WordNet   license wordnet

「addicted to a drug」
dependant, drug-addicted, hooked, strung-out

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「contingent on something else」
dependant, qualified

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「(of a clause) unable to stand alone syntactically as a complete sentence; "a subordinate (or dependent) clause functions as a noun or adjective or adverb within a sentence"」
subordinate


C」

  [★]

WordNet   license wordnet

「the 3rd letter of the Roman alphabet」
c

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「(music) the keynote of the scale of C major」

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「a general-purpose programing language closely associated with the UNIX operating system」

PrepTutorEJDIC   license prepejdic

「carbonの化学記号」

voltage」

  [★]

  • n.
electric potentialelectrical potentialpotential

WordNet   license wordnet

「the rate at which energy is drawn from a source that produces a flow of electricity in a circuit; expressed in volts」
electromotive force, emf

PrepTutorEJDIC   license prepejdic

「電圧,電圧量,ボルト数」

channels」

  [★] チャネル

WordNet   license wordnet

「official routes of communication; "you have to go through channels"」




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