WordNet

the process of declining from a higher to a lower level of effective power or vitality or essential quality (同)devolution
passing from a more complex to a simpler biological form (同)retrogression
relating to or resembling or derived from or containing glass; "vitreous rocks"; "vitreous silica"
of or relating to or constituting the vitreous humor of the eye; "the vitreous chamber"

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1. 網膜剥離 retinal detachment
2. 加齢黄斑変性：臨床像、病因、および診断 age related macular degeneration clinical presentation etiology and diagnosis
3. 加齢黄斑変性：治療および予防 age related macular degeneration treatment and prevention
4. 真菌による眼内炎の治療 treatment of endophthalmitis due to molds
5. パーキンソン病の診断 diagnosis of parkinson disease

Intravitreal Implantation of Genetically Modified Autologous Bone Marrow-Derived Stem Cells for Treating Retinal Disorders.

Tracy CJ1,2, Sanders DN3,4, Bryan JN5, Jensen CA6, Castaner LJ7, Kirk MD8, Katz ML9.
Advances in experimental medicine and biology.Adv Exp Med Biol.2016;854:571-7. doi: 10.1007/978-3-319-17121-0_76.
A number of retinal degenerative diseases may be amenable to treatment with continuous intraocular delivery of therapeutic agents that cannot be delivered effectively to the retina via systemic or topical administration. Among these disorders are lysosomal storage diseases resulting from deficiencie
PMID 26427461

Klein A, Loewenstein A.
Developments in ophthalmology.Dev Ophthalmol.2016;55:232-45. doi: 10.1159/000431199. Epub 2015 Oct 26.
Bevacizumab (Avastin) is a recombinant humanized monoclonal immunoglobulin antibody that has two antigen-binding domains and blocks all active forms of vascular endothelial growth factor-A. It was originally designed and is still in use as antitumor agent (for colorectal and non-small cell lung canc
PMID 26502311

Intravitreal administration of known phototoxicants in the rabbit fails to produce phototoxicity: implications for phototoxicity testing of intravitreally administered small molecule therapeutics.

Thackaberry EA1, Farman C1, Bantseev V1, Schuetz C1, Baker JF2, Brown MH3, Learn DB4.
Cutaneous and ocular toxicology.Cutan Ocul Toxicol.2015 Dec;34(4):265-70. doi: 10.3109/15569527.2014.961070. Epub 2014 Nov 6.
CONTEXT: Intravitreal (ITV) dosing has become a clinically important route of administration for the treatment of uveitis, endophthalmitis, retinal vein occlusion, diabetic macular edema and age-related macular degeneration. Despite this, there are no validated non-clinical models of phototoxicity f
PMID 25373486

園田祥三,山下敏史,鈴木亮 [他],丸山一雄,坂本泰二
薬学雑誌. 乙号 133(12), 1269-1276, 2013
… Eye has characteristic structure sensory cells are arranged along the eye wall, and is filled inside with vitreous body. … In recent years, intravitreal injection of anti-vascular endothelial growth factor (VEGF) agent had widely spread, and numerous number of patients who suffered ocular angiogenic disease such as diabetic retinopathy, age-related macular degeneration and retinal vascular occlusion for the disease, were treated and spared the blindness. …
NAID 130003382278