vitamin K-dependent proteins

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英文文献

  • Warfarin, a potential pollutant in aquatic environment acting through Pxr signaling pathway and γ-glutamyl carboxylation of vitamin K-dependent proteins.
  • Fernández I1, Santos A2, Cancela ML3, Laizé V2, Gavaia PJ2.
  • Environmental pollution (Barking, Essex : 1987).Environ Pollut.2014 Nov;194:86-95. doi: 10.1016/j.envpol.2014.07.015. Epub 2014 Aug 4.
  • Warfarin-induced vitamin K (VK) recycling impairment is used worldwide as a rodenticide and human thromboembolic prophylactic. Since VK metabolism/signaling pathways have been conserved throughout vertebrate evolution, its release to the environment might impact on aquatic organisms. Present study a
  • PMID 25094061
  • Vitamin K: dietary intake and requirements in different clinical conditions.
  • Harshman SG1, Saltzman E, Booth SL.
  • Current opinion in clinical nutrition and metabolic care.Curr Opin Clin Nutr Metab Care.2014 Sep 17. [Epub ahead of print]
  • PURPOSE OF REVIEW: Vitamin K is an enzyme cofactor for the carboxylation of vitamin K-dependent proteins. Functions include coagulation and regulation of calcification. Different clinical conditions may alter vitamin K requirements by affecting vitamin K status and vitamin K-dependent proteins carbo
  • PMID 25232640

和文文献

  • 血管石灰化病変におけるビタミンK2のosteopontin(OPN),matrix gla-protein(MGP)mRNA発現への影響
  • 加藤 徳介,渡辺 誠,黒木 亜紀,小椋 陽介,杉崎 徹三,秋澤 忠男
  • 昭和医学会雑誌 69(2), 174-181, 2009
  • … 慢性腎不全患者における最大の死因は心血管系合併症であり,その機序として動脈石灰化が注目されている.また近年,ビタミンK(VitK)の血管石灰化予防効果が報告されている.しかし,尿毒症下での血管石灰化機序とVitKの役割はいまだ不明な点が多い.そこで活性型ビタミンD3(VitD3)誘導血管石灰化腎不全モデルを作成し,腎不全病態下におけるVitK2の血管石灰化抑制作用をin vivoで検討した.方法として,8週齡SD …
  • NAID 130000852967

関連リンク

1. Vitam Horm. 2000;58:355-89. Vitamin K-dependent proteins. Nelsestuen GL, Shah AM, Harvey SB. Vitamin K is required for the synthesis of gamma-carboxyglutamate (Gla) during postribosomal protein modification. Substrates ...
Figure 1. Hepatic and peripheral carboxylation of VKDPs. Vitamin K-dependent proteins undergo carboxylation to become biologically active, requiring vitamin K as a cofactor in the conversion. In hepatic ...

関連画像

 VITAMIN K-DEPENDENT PROTEINS DURINGVitamin K: MedlinePlus Supplements Vitamin K-dependent Proteins, Warfarin Vitamin K Dependent Proteins and the Role  treat poisoning with vitamin K antagonistsVitamin K Dependent Proteins and the Role


★リンクテーブル★
関連記事dependent」「King」「K」「protein」「vitamin

dependent」

  [★]

  • adj.
  • 依存性の、依存的な、依存型の、依存の
dependdependencedependencydependently

WordNet   license wordnet

「relying on or requiring a person or thing for support, supply, or what is needed; "dependent children"; "dependent on moisture"」

PrepTutorEJDIC   license prepejdic

「『頼っている』,依存している,従属している / 扶養される人(家族)」

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「addicted to a drug」
dependant, drug-addicted, hooked, strung-out

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「contingent on something else」
dependant, qualified

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「(of a clause) unable to stand alone syntactically as a complete sentence; "a subordinate (or dependent) clause functions as a noun or adjective or adverb within a sentence"」
subordinate


King」

  [★]

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「United States guitar player and singer of the blues (born in 1925)」
B. B. King, Riley B King

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「United States woman tennis player (born in 1943)」
Billie Jean King, Billie Jean Moffitt King

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「United States charismatic civil rights leader and Baptist minister who campaigned against the segregation of Blacks (1929-1968)」
Martin Luther King, Martin Luther King Jr.

K」

  [★]

WordNet   license wordnet

「street names for ketamine」
jet, super acid, special K, honey oil, green, cat valium, super C

WordNet   license wordnet

「the 11th letter of the Roman alphabet」
k

PrepTutorEJDIC   license prepejdic

「Kelvin / Kindergarten / (チェスの)King / kalium(ラテン語)(=potassium)の化学記号」


protein」

  [★] 蛋白質

WordNet   license wordnet

「any of a large group of nitrogenous organic compounds that are essential constituents of living cells; consist of polymers of amino acids; essential in the diet of animals for growth and for repair of tissues; can be obtained from meat and eggs and milk and legumes; "a diet high in protein"」

PrepTutorEJDIC   license prepejdic

「蛋白(たんばく)質」

vitamin」

  [★] ビタミン

WordNet   license wordnet

「any of a group of organic substances essential in small quantities to normal metabolism」

PrepTutorEJDIC   license prepejdic

「『ビタミン』,栄養素(身体の喜常な機能を維持するために少量ながら必要な有機化合物)」




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