WordNet

a determining or causal element or factor; "education is an important determinant of ones outlook on life" (同)determiner, determinative, determining factor, causal factor
a square matrix used to solve simultaneous equations
extreme hostility; "the virulence of the malicious old man" (同)virulency
extreme harmfulness (as the capacity of a microorganism to cause disease); "the virulence of the plague" (同)virulency

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1. 尿路感染症における細菌付着およびその他の病原因子 bacterial adherence and other virulence factors for urinary tract infection
2. エルシニア感染の微生物学および病因 microbiology and pathogenesis of yersinia infections
3. 肺炎桿菌感染症の微生物学および病因 microbiology and pathogenesis of klebsiella pneumoniae infection
4. クリプトコッカス-ネオフォルマン感染症の微生物学および疫学 microbiology and epidemiology of cryptococcus neoformans infection
5. A群レンサ球菌：病原性因子および発症機序 group a streptococcus virulence factors and pathogenic mechanisms

Piliation of Invasive Streptococcus pneumoniae Isolates in the Era before Pneumococcal Conjugate Vaccine Introduction in Malawi.

Kulohoma BW, Gray K, Kamng'ona A, Cornick J, Bentley SD, Heyderman RS, Everett DB.SourceThe Malawi-Liverpool-Wellcome Trust Clinical Research Programme, Blantyre, Malawi.
Clinical and vaccine immunology : CVI.Clin Vaccine Immunol.2013 Nov;20(11):1729-35. doi: 10.1128/CVI.00403-13. Epub 2013 Sep 11.
The pneumococcal pilus has been shown to be an important determinant of adhesion and virulence in mouse models of colonization, pneumonia, and bacteremia. A pilus is capable of inducing protective immunity, supporting its inclusion in next-generation pneumococcal protein vaccine formulations. Whethe
PMID 24027261

D-Alanine Modification of a Protease-Susceptible Outer Membrane Component by the Bordetella pertussis dra Locus Promotes Resistance to Antimicrobial Peptides and Polymorphonuclear Leukocyte-Mediated Killing.

Taneja NK, Ganguly T, Bakaletz LO, Nelson KJ, Dubey P, Poole LB, Deora R.SourceDepartment of Microbiology and Immunology.
Journal of bacteriology.J Bacteriol.2013 Nov;195(22):5102-11. doi: 10.1128/JB.00510-13. Epub 2013 Sep 6.
Bordetella pertussis is the causative agent of pertussis, a highly contagious disease of the human respiratory tract. Despite very high vaccine coverage, pertussis has reemerged as a serious threat in the United States and many developing countries. Thus, it is important to pursue research to discov
PMID 24013634

Regulation of Host Hemoglobin Binding by the Staphylococcus aureus Clp Proteolytic System.

Farrand AJ, Reniere ML, Ingmer H, Frees D, Skaar EP.SourceDepartment of Pathology, Microbiology, and Immunology, Vanderbilt University School of Medicine, Nashville, Tennessee, USA.
Journal of bacteriology.J Bacteriol.2013 Nov;195(22):5041-50. doi: 10.1128/JB.00505-13. Epub 2013 Aug 30.
Protein turnover is a key process for bacterial survival mediated by intracellular proteases. Proteolytic degradation reduces the levels of unfolded and misfolded peptides that accumulate in the cell during stress conditions. Three intracellular proteases, ClpP, HslV, and FtsH, have been identified
PMID 23995637

Quantitative and Qualitative Involvement of P3N-PIPO in Overcoming Recessive Resistance against Clover yellow vein virus in Pea Carrying cyv1

Choi Sun Hee,Hagiwara-Komoda Yuka,S. Nakahara Kenji,Atsumi Go,Shimada Ryoko,Hisa Yusuke,Naito Satoshi,Uyeda Ichiro
Journal of Virology 87(13), 7326-7337, 2013-07
… Moreover, P3N-PIPO quantitatively affected the virulence of Cl-no30 in cyv1 pea. … This is the first report showing that P3N-PIPO is a virulence determinant in plants resistant to a potyvirus. …
NAID 120005372269

Evaluation of Recombinant Forms of the Shiga Toxin Variant Stx2eB Subunit and Non-Toxic Mutant Stx2e as Vaccine Candidates against Porcine Edema Disease

SATO Toshio,MATSUI Takeshi,TAKITA Eiji,KADOYAMA Yumiko,MAKINO Sou-Ichi,KATO Ko,SAWADA Kazutoshi,HAMABATA Takashi
Journal of Veterinary Medical Science 75(10), 1309-1315, 2013
… Stx2e is classified as a 1A5B-type toxin and is a decisive virulence determinant of ED. The single A subunit of Stx2e possesses enzymatic activity and is accompanied by a pentamer of B subunits, which binds to the host receptor and delivers the A subunit into the cell. …
NAID 130003362223

Construction of a replicon and an infectious cDNA clone of the Sofjin strain of the Far-Eastern subtype of tick-borne encephalitis virus

Takano Ayako,Yoshii Kentaro,Omori-Urabe Yuki,Yokozawa Kana,Kariwa Hiroaki,Takashima Ikuo
Archives of Virology 156(11), 1931-1941, 2011-11
… The recombinant viruses showed similar virulence characteristics to those of the parental virus. … These replicons and infectious cDNA clones are useful in revealing the viral molecular determinant involved in the replication and pathogenicity of TBEV. …
NAID 120004856987