WordNet

natural bases containing nitrogen found in plants
a genus of coarse poisonous perennial herbs; sometimes placed in subfamily Melanthiaceae (同)genus Veratrum

PrepTutorEJDIC

全文を閲覧するには購読必要です。 To read the full text you will need to subscribe.

Antitumor activity of isosteroidal alkaloids from the plants in the genus Veratrum and Fritillaria.

Shang Y1, Du Q1, Liu S1, Staadler M2, Wang S1, Wang D3.
Current protein & peptide science.Curr Protein Pept Sci.2017 Jan 5. [Epub ahead of print]
Isosteroidal alkaloids are a category of promising bioactive compounds which mostly exist in plants of genus Veratrum and Fritillaria. The pharmacological activities of isosteroidal alkaloids include antihypertensive, antitussive, anti-inflammatory, antithrombosis, among others. Recently, some studi
PMID 28059041

Three new alkaloids from Veratrum grandiflorum Loes with inhibition activities on Hedgehog pathway.

Gao L1, Chen F2, Li X3, Xu S4, Huang W5, Ye Y6.
Bioorganic & medicinal chemistry letters.Bioorg Med Chem Lett.2016 Oct 1;26(19):4735-8. doi: 10.1016/j.bmcl.2016.08.040. Epub 2016 Aug 16.
Three new steroidal alkaloids 1-3, together with four known compounds 4-7, were isolated from the ethanol extract of Veratrum grandiflorum Loes. Their structures were elucidated by NMR (1D and 2D NMR) and MS spectroscopic data. The inhibition activities on Hedgehog (Hh) pathway were evaluated using
PMID 27567371

Pharmacokinetics and metabolism study of veratramine in mice after oral administration using LC-MS/MS.

Cong Y1, Zhang JL2, Li SS1, Shen S1, Wang JY1, Cai Z3.
Biomedical chromatography : BMC.Biomed Chromatogr.2016 Sep;30(9):1515-22. doi: 10.1002/bmc.3717. Epub 2016 Apr 3.
A simple and sensitive high-performance liquid chromatography coupled with hybrid triple quadrupole-linear ion trap mass spectrometry (Q-trap-MS) method was developed and validated for the determination of veratramine, the major bioactive and neurotoxic component in Veratrum nigrum L. Veratramine an
PMID 26972867

Veramadines A and B, New Steroidal Alkaloids from Veratrum maackii var. japonicum

Tanaka Naonobu,Suto Shohei,Kobayashi Jun'ichi
Chemical and Pharmaceutical Bulletin 59(7), 909-912, 2011
… Two new steroidal alkaloids possessing a cevanine-type skeleton, veramadines A (1) and B (2), were isolated from the aerial parts of Veratrum maackii var. …
NAID 130000748031

高沢研丞,梅澤和夫,関知子,守田誠司,中川儀英,山本五十年,猪口貞樹
日本救急医学会雑誌 = Journal of Japanese Association for Acute Medicine 15(5), 185-189, 2004-05-15
NAID 10013603135

高沢研丞,梅澤和夫,関知子,守田誠司,中川儀英,山本五十年,猪口貞樹
日本救急医学会雑誌 15(5), 185-189, 2004
… The plant was later revealed to be Veratrum album. … Veratrum album is a toxic wild plant that is frequently encountered in Japan and is often mistaken for Hosta sieboldiana. … Since acute intoxication by veratrum alkaloids may cause severe parasympathetic symptoms, including profound hypotension and bradycardia, early recognition and treatment are required. …
NAID 130003437647