vasopressin receptor antagonist

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出典(authority):フリー百科事典『ウィキペディア(Wikipedia)』「2014/02/02 19:33:59」(JST)

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  • Safety of add-on tolvaptan in patients with furosemide-resistant congestive heart failure complicated by advanced chronic kidney disease: a sub-analysis of a pharmacokinetics/ pharmacodynamics study.
  • Tominaga N, Kida K, Matsumoto N, Akashi YJ, Miyake F, Kimura K, Shibagaki Y.
  • Clinical nephrology.Clin Nephrol.2015 Jul;84(7):29-38. doi: 10.5414/CN108457.
  • BACKGROUND: Treatment of congestive heart failure (CHF) with loop diuretics, such as furosemide, may be associated with complications, including worsening renal function and metabolic or electrolyte disturbances. Coadministration of tolvaptan, a selective vasopressin V2 receptor antagonist, can amel
  • PMID 25997504
  • Oral vasopressin receptor antagonist tolvaptan in right heart failure due to pulmonary hypertension.
  • Tamura Y1, Kimura M2, Takei M2, Ono T2, Kuwana M3, Satoh T4, Fukuda K2, Humbert M5.
  • The European respiratory journal.Eur Respir J.2015 Jul;46(1):283-6. doi: 10.1183/09031936.00044915. Epub 2015 Apr 30.
  • PMID 25929949


  • バソプレッシンV2アンタゴニストと心不全 (内分泌) -- (臨床分野での進歩)
  • 佐藤 直樹
  • Annual review. 糖尿病・代謝・内分泌 2012(-) (-), 230-233, 2012-00-00
  • NAID 40019175031
  • Correction of Hyponatremia by Tolvaptan Before Left Ventricular Assist Device Implantation
  • Imamura Teruhiko,Kinugawa Koichiro,Shiga Taro,Kato Naoko,Endo Miyoko,Inaba Toshiro,Maki Hisataka,Hatano Masaru,Yao Atsushi,Hirata Yasunobu,Nishimura Takashi,Kyo Shunei,Ono Minoru,Nagai Ryozo
  • International Heart Journal 53(6), 391-393, 2012
  • … Tolvaptan, an oral vasopressin-2-receptor antagonist, has been previously reported to improve congestion and correct hyponatremia through increased excretion of free water. …
  • NAID 130002528818


A vasopressin receptor antagonist (VRA) is an agent which interferes with action at the vasopressin receptors. Most commonly VRAs are used in the treatment of hyponatremia, especially in patients with congestive heart failure, liver cirrhosis ...
Therapeutic potential of vasopressin receptor antagonists. Ali F, Guglin M, Vaitkevicius P, Ghali JK. Heart Failure Program, Wayne State University, Detroit, Michigan, USA. Arginine vasopressin (AVP) is a neuropeptide hormone that plays an ...



関連記事antagonist」「vasopressin」「receptor」「vasopressin receptor


  [★] 拮抗薬

WordNet   license wordnet

「a drug that neutralizes or counteracts the effects of another drug」

WordNet   license wordnet

「a muscle that relaxes while another contracts; "when bending the elbow the triceps are the antagonist"」

PrepTutorEJDIC   license prepejdic



  [★] バソプレシン

WordNet   license wordnet

「hormone secreted by the posterior pituitary gland (trade name Pitressin) and also by nerve endings in the hypothalamus; affects blood pressure by stimulating capillary muscles and reduces urine flow by affecting reabsorption of water by kidney tubules」
antidiuretic hormone, ADH, Pitressin


  [★] 受容体

WordNet   license wordnet

「a cellular structure that is postulated to exist in order to mediate between a chemical agent that acts on nervous tissue and the physiological response」

PrepTutorEJDIC   license prepejdic

「=sense organ / 受信装置」

vasopressin receptor」

  [★] バソプレシン受容体