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1. 肥満細胞由来のメディエーター mast cell derived mediators
2. 腎細胞癌の免疫療法 immunotherapy of renal cell carcinoma
3. アレルギー性結膜炎：臨床症状および診断 allergic conjunctivitis clinical manifestations and diagnosis
4. 肥満細胞：増殖・分化、識別、および生理学的役割 mast cells development identification and physiologic roles
5. アナフィラキシーの病態生理 pathophysiology of anaphylaxis

English Journal

Role of the receptor for advanced glycation endproducts (RAGE) in retinal vasodegenerative pathology during diabetes in mice.

McVicar CM1, Ward M, Colhoun LM, Guduric-Fuchs J, Bierhaus A, Fleming T, Schlotterer A, Kolibabka M, Hammes HP, Chen M, Stitt AW.
Diabetologia.Diabetologia.2015 May;58(5):1129-37. doi: 10.1007/s00125-015-3523-x. Epub 2015 Feb 17.
AIMS/HYPOTHESIS: The receptor for AGEs (RAGE) is linked to proinflammatory pathology in a range of tissues. The objective of this study was to assess the potential modulatory role of RAGE in diabetic retinopathy.METHODS: Diabetes was induced in wild-type (WT) and Rage (-/-) mice (also known as Ager
PMID 25687235

Masuda T1, Shimazawa M2, Hara H3.
European journal of pharmacology.Eur J Pharmacol.2015 Feb 15;749:161-3. doi: 10.1016/j.ejphar.2014.10.007. Epub 2014 Oct 18.
Kallikrein is a serine protease involved in the kallikrein-kinnin system. Kallikrein is derived from the blood plasma or tissue, and is correlated with aggravation and improvement in eye diseases, such as, glaucoma, diabetic retinopathy, age-related macular degeneration, and ocular ischemic syndrome
PMID 25448306

Glyceraldehyde-derived pyridinium (GLAP) evokes oxidative stress and inflammatory and thrombogenic reactions in endothelial cells via the interaction with RAGE.

Matsui T1, Oda E2, Higashimoto Y3, Yamagishi S4.
Cardiovascular diabetology.Cardiovasc Diabetol.2015 Jan 8;14:1. doi: 10.1186/s12933-014-0162-3.
BACKGROUND: We have previously shown that serum levels of glyceraldehyde-derived advanced glycation end products (Gly-AGEs) are elevated under oxidative stress and/or diabetic conditions and associated with insulin resistance, endothelial dysfunction and vascular inflammation in humans. Further, Gly
PMID 25582325

北野滋彦,KITANO Shigehiko
東京女子医科大学雑誌 76(8/9), 361-367, 2006-09
… It is characterized by gradually progressive alteration in the retinal microvasculature, leading to retinal nonperfusion, increased vasopermeability, and pathologic intraocular proliferation of retinal vessels. …
NAID 110007525526

山本一博
日本耳鼻咽喉科學會會報 99(4), 533-543, 1996-04-20
… However, in those patients having a continuous watery discharge even after TCA treatment, the function of the remaining nasal glands might be responsible for the symptom, although the contribution of VIP to the increase in vasopermeability should also be taken into consideration. …
NAID 10006826392

安藤和正 [他],礒野恵美子,久保田賢子,芋川英紀,井上肇,石田寛友,荻野洋一
日本薬理学雑誌 96(6), 323-332, 1990
… 4) Vasopermeability of the ear was depressed with antihistamine treatment, but non-steroidal anti-inflammatory drugs had no effect. …
NAID 130000758998