WordNet

bring disorder to (同)disarray
a physical condition in which there is a disturbance of normal functioning; "the doctor prescribed some medicine for the disorder"; "everyone gets stomach upsets from time to time" (同)upset
a disturbance of the peace or of public order
relating to the nerves and muscles that cause the blood vessels to constrict or dilate
not arranged in order (同)unordered

PrepTutorEJDIC

〈U〉『無秩序』,混乱,乱雑(confusion) / 《しばしば複数形で》(社会的・政治的な)粉争,騒動 / 〈C〉(肉体的・精神的な)不調,異常,障害 / …‘の'秩序を乱す / 〈心身〉‘に'異常を起こさせる

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1. 成人における転換性障害：用語、診断および鑑別診断 conversion disorder in adults terminology diagnosis and differential diagnosis
2. レビー小体型認知症の臨床的特徴および診断 clinical features and diagnosis of dementia with lewy bodies
3. 無症候性心筋虚血：疫学および病因 silent myocardial ischemia epidemiology and pathogenesis
4. 新生児における急性腎障害（急性腎不全） acute kidney injury acute renal failure in the newborn
5. 女性における性機能障害：管理 sexual dysfunction in women management

English Journal

Cerebral hemodynamic changes at basilar artery in patients with obstructive sleep apnea syndrome. A case-control study.

Jiménez Caballero PE, Coloma Navarro R, Segura Martín T, Ayo Martín O.Author information Hospital San Pedro de Alcántara, Cáceres, Spain.AbstractINTRODUCTION: Obstructive sleep apnea syndrome (OSAS) is characterized in polysomnography by recurrent airflow obstruction during sleep. The underlying pathogenic mechanisms of neuropsychological and cerebrovascular events in patients with OSAS have not been clarified unequivocally.
Acta neurologica Scandinavica.Acta Neurol Scand.2014 Feb;129(2):80-4. doi: 10.1111/ane.12156. Epub 2013 Jun 13.
INTRODUCTION: Obstructive sleep apnea syndrome (OSAS) is characterized in polysomnography by recurrent airflow obstruction during sleep. The underlying pathogenic mechanisms of neuropsychological and cerebrovascular events in patients with OSAS have not been clarified unequivocally.MATERIAL AND METH
PMID 23763490

Effects of neutral endopeptidase (neprilysin) inhibition on the response to other vasoactive peptides in small human resistance arteries: studies with thiorphan and omapatrilat.

Dalzell JR, Seed A, Berry C, Whelan CJ, Petrie MC, Padmanabhan N, Clarke A, Biggerstaff F, Hillier C, McMurray JJ.Author information British Heart Foundation Cardiovascular Research Centre, University of Glasgow, Glasgow, UK.AbstractPURPOSE: New compounds with neprilysin or neutral endopeptidase (NEP) inhibiting activity are under clinical investigation in heart failure and hypertension. We investigated the effect of NEP inhibition on the functional vasomotor responses to a range of vasoactive peptides in human blood vessels.
Cardiovascular therapeutics.Cardiovasc Ther.2014 Feb;32(1):13-8. doi: 10.1111/1755-5922.12053.
PURPOSE: New compounds with neprilysin or neutral endopeptidase (NEP) inhibiting activity are under clinical investigation in heart failure and hypertension. We investigated the effect of NEP inhibition on the functional vasomotor responses to a range of vasoactive peptides in human blood vessels.ME
PMID 24138103

Pathophysiology of hypertension: interactions between macro and microvascular alterations through endothelial dysfunction.

Yannoutsos A, Levy BI, Safar ME, Slama G, Blacher J.Author information aDiagnosis and Therapeutics Centre, Hypertension and Cardiovascular Prevention Unit, Hôtel-Dieu Hospital bPARCC, INSERM U970, and Blood and Vessels Institute, Lariboisière Hospital, Paris, France.AbstractHypertension is a multifactorial systemic chronic disorder through functional and structural macrovascular and microvascular alterations. Macrovascular alterations are featured by arterial stiffening, disturbed wave reflection and altered central to peripheral pulse pressure amplification. Microvascular alterations, including altered wall-to-lumen ratio of larger arterioles, vasomotor tone abnormalities and network rarefaction, lead to disturbed tissue perfusion and susceptibility to ischemia. Central arterial stiffness and microvascular alterations are common denominators of organ damages. Vascular alterations are intercorrelated, amplifying the haemodynamic load and causing further damage in the arterial network. A plausible precursor role of vascular alterations in incident hypertension provides new insights for preventive and therapeutic strategies targeting macro and microvasculature. Cumulative metabolic burden and oxidative stress lead to chronic endothelial injury, promoting structural and functional vascular alterations, especially in the microvascular network. Pathophysiology of hypertension may then be revisited, based on both macrovascular and microvascular alterations, with a precursor role of endothelial dysfunction for the latter.
Journal of hypertension.J Hypertens.2014 Feb;32(2):216-24. doi: 10.1097/HJH.0000000000000021.
Hypertension is a multifactorial systemic chronic disorder through functional and structural macrovascular and microvascular alterations. Macrovascular alterations are featured by arterial stiffening, disturbed wave reflection and altered central to peripheral pulse pressure amplification. Microvasc
PMID 24270179

Japanese Journal

更年期うつ病におけるホルモン療法と抗うつ薬併用の効果 : 文献的検証

山下晃弘,佐藤弘樹,重村淳,野村総一郎,吉野相英
女性心身医学 18(1), 125-131, 2013-07-15
NAID 110009624358

下鼻甲介手術を併施した後鼻神経切断術の有効性の検討

上條篤,黒田優美,初鹿恭介 [他],森山元大,松岡伴和,山本卓典,加瀬康弘,増山敬祐
アレルギー 62(1), 47-53, 2013-01-30
【背景】ヴィディアン神経切断術は血管運動性鼻炎や難治性通年性アレルギー性鼻炎に有効であるが,一方で,ドライアイや三叉神経痛などの合併症の問題からほとんど施行されなくなった.これに代わり,内視鏡下に後鼻神経を切断する術式が開発され,最近では一般的になりつつある.今回,当科で後鼻神経切断術を行った症例にアンケート調査を施行し,当手術の妥当性,反省点を明らかにすべく検討を試みた.【対象と方法】2005年 …
NAID 110009580191

Testing Endothelial Function and its Clinical Relevance

Poredos Pavel,Jezovnik Mateja Kaja
Journal of Atherosclerosis and Thrombosis 20(1), 1-8, 2013
… As endothelial dysfunction is a diffuse-systemic disorder, the peripheral arteries, because of their accessibility, represent the basis for assessment of endothelial dysfunction. … FMD measures the endothelial vasomotor response during reactive hyperemia, but it does not provide information concerning the control of arterial tone at rest. …
NAID 130004444643