uronic acid

ウロン酸

関

uronate

WordNet

1. street name for lysergic acid diethylamide (同)back breaker, battery-acid, dose, dot, Elvis, loony toons, Lucy in the sky with diamonds, pane, superman, window pane, Zen
2. any of various water-soluble compounds having a sour taste and capable of turning litmus red and reacting with a base to form a salt
3. having the characteristics of an acid; "an acid reaction"

PrepTutorEJDIC

1. 酸性の / 酸味のある,すっぱい(sour) / (言葉・態度などが)厳しい,しんらつな / 酸 / すっぱいもの / 《俗》=LSD

Wikipedia preview

出典(authority):フリー百科事典『ウィキペディア（Wikipedia）』「2016/10/21 13:57:05」(JST)

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The β-D form of glucuronic acid (after oxidization).

Glucose (before oxidization)

The Fischer projections of glucose and glucuronic acid. Glucose's terminal carbon's primary alcohol group has been oxidized to a carboxylic acid.

Uronic acids (/jʊˈrɒnᵻk/) are a class of sugar acids with both carbonyl and carboxylic acid functional groups. They are sugars in which the terminal carbon's hydroxyl group has been oxidized to a carboxylic acid. Oxidation of the terminal aldehyde instead yields an aldonic acid, while oxidation of both the terminal hydroxyl group and the aldehyde yields an aldaric acid. The names of uronic acids are generally based on their parent sugars, for example, the uronic acid analog of glucose is glucuronic acid. Uronic acids derived from hexoses are known as hexuronic acids and uronic acids derived from pentoses are known as penturonic acids.

Examples

Some of these compounds have important biochemical functions; for example, many wastes in the human body are excreted in the urine as their glucuronate salts, and iduronic acid is a component of some structural complexes such as proteoglycans.

References

External links

• Uronic Acids at the US National Library of Medicine Medical Subject Headings (MeSH)
• Synthesis at chembio.uoguelph.ca

UpToDate Contents

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• 1. 尿酸のバランス uric acid balance
• 2. 出産時の臍帯血酸塩基分析 umbilical cord blood acid base analysis at delivery
• 3. 妊娠中の葉酸補充 folic acid supplementation in pregnancy
• 4. ポルフィリン症：概要 porphyrias an overview
• 5. 疾患予防におけるビタミン補給 vitamin supplementation in disease prevention

English Journal

• The antioxidant activities effect of neutral and acidic polysaccharides from Epimedium acuminatum Franch. on Caenorhabditis elegans.

• Xu Z1, Feng S1, Shen S1, Wang H1, Yuan M1, Liu J1, Huang Y1, Ding C2.
• Carbohydrate polymers.Carbohydr Polym.2016 Jun 25;144:122-30. doi: 10.1016/j.carbpol.2016.02.041. Epub 2016 Feb 18.
• A neutral polysaccharide (EAP-1N) and an acidic polysaccharide (EAP-2A) were purified from Epimedium acuminatum by DEAE-52 cellulose anion-exchange chromatography and gel-filtration chromatography. Their structures were characterized by chemical composition analysis, high-performance size exclusion
• PMID 27083801

• Pectin content and composition from different food waste streams.

• Müller-Maatsch J1, Bencivenni M1, Caligiani A1, Tedeschi T1, Bruggeman G2, Bosch M3, Petrusan J4, Van Droogenbroeck B5, Elst K6, Sforza S7.
• Food chemistry.Food Chem.2016 Jun 15;201:37-45. doi: 10.1016/j.foodchem.2016.01.012. Epub 2016 Jan 6.
• In the present paper, 26 food waste streams were selected according to their exploitation potential and investigated in terms of pectin content. The isolated pectin, subdivided into calcium bound and alkaline extractable pectin, was fully characterized in terms of uronic acid and other sugar composi
• PMID 26868545

• Influences of acidic reaction and hydrolytic conditions on monosaccharide composition analysis of acidic, neutral and basic polysaccharides.

• Wang QC1, Zhao X2, Pu JH1, Luan XH1.
• Carbohydrate polymers.Carbohydr Polym.2016 Jun 5;143:296-300. doi: 10.1016/j.carbpol.2016.02.023. Epub 2016 Feb 10.
• Monosaccharide composition analysis is important for structural characterization of polysaccharides. To investigate the influences of acidic reaction and hydrolytic conditions on monosaccharide composition analysis of polysaccharides, we chose alginate, starch, chitosan and chondroitin sulfate as re
• PMID 27083372

Japanese Journal

• ウメ 2 品種の果実軟化過程における 細胞壁多糖類の分解特性

• 土田 靖久,薬師寺 博,大江 孝明,根来 圭一,我藤 伸樹,小谷 竜也,大西 由里子,小畑 貴路,田村 基
• Journal of the Japanese Society for Horticultural Science 83(1), 81-89, 2014
• 和歌山県のウメ主要品種'南高'果実は'古城'に比べて柔らかい肉質を持っている．そのため，これらの品種の加工適性には違いがある．そこで筆者らは，果肉硬度に影響を与える細胞壁多糖類の分解特性を，これら 2 品種の果実軟化過程において調査した．'古城'の果肉硬度は未熟期と適熟期の間は変化がなく，適熟期から完熟期の間で低下した．一方'南高'では未熟期から速やかに低下し，'古城'に比べて低く推移した．これら …
• NAID 130004510807

• 養殖ニジマス頭部軟骨の部位別プロテオグリカン含有量と分子量分布の比較

• 三浦 絢子,加藤 陽治
• 日本食品科学工学会誌 61(5), 206-211, 2014
• 津軽海峡で養殖されているニジマス「海峡サーモン」について，新たなPG原料としての有効性を探るため，頭部軟骨を脳周辺部，前頭部，あご上部，鼻先目周辺部の4部位に分画し，部位毎のPG含有量と分子量分布を比較検討した．その結果，（1）脳周辺部と鼻先目周辺部の軟骨量については，全軟骨中で占める割合が33%および32%であり，前頭部やあご上部の20%および15%に比べて多いが，各部位の軟骨湿潤重量1gあたり …
• NAID 130004488680

• Cytotoxicity and Inhibition of Nitric Oxide in Lipopolysaccharide Induced Mammalian Cell Lines by Aqueous Extracts of Brown Seaweed

• Jaswir Irwandi,Monsur Hammed Ademola,Simsek Senay,Amid Azura,Alam Zahangir,Salleh Mohammad Noor bin,Tawakalit Asiyanbi-Hammed,Octavianti Fitri
• Journal of Oleo Science 63(8), 787-794, 2014
• … The chemical compositions of the extracts showed that the percentage of sulfate ions as well as uronic acid and total sugar content varied significantly. …
• NAID 130004436164

Related Links

• Uronic Acid definition of Uronic Acid in the Free Online ...

uronic acid [yə′rän·ik ′as·əd] (organic chemistry) One of the compounds that are similar to sugars, except that the terminal carbon has been oxidized from the alcohol to a carboxyl group; for example, galacturonic acid and glucuronic ...

• Uronic-acid | Define Uronic-acid at Dictionary.com

uronic acid u·ron·ic acid (yu-rŏn'ĭk) n. A product of the oxidation of sugar occurring in various polysaccharides and in urine and containing both an aldehyde and a carboxyl group.

Related Pictures

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★リンクテーブル★

リンク元	「グリコサミノグリカン」「uronate」「ウロン酸」
拡張検索	「glucuronic acid」「tetragalacturonic acid hydroxymethylester」「iduronic acid」

「グリコサミノグリカン」

　　[★]

英

glycosaminoglycan

同

ムコ多糖 mucopolysaccharide

関

プロテオグリカン proteoglycan、コンドロイチン硫酸、酸性ムコ多糖体症、多糖、デルマタン硫酸

概念

• 細胞間マトリックスを埋める多糖
• 粘稠性と弾力性が高い粘液
• 枝分かれのない多糖で、ウロン酸(uronic acid)とヘキソサミン残基(アミノ糖 amino sugar)が交互につながっている
• グリコサミノグリカンがタンパク質に結合した化合物がプロテオグリカン

グリコサミノグリカン + 蛋白質　＝　プロテオグリカン

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グリコサミノグリカン	ウロン酸	ヘキソサミン残基	結合			局在	-COO-	-SO3-
ヒアルロン酸	D-グルクロン酸	N-アセチル-D-グルコサミン	GlcUA	β1-3	GlcNAc	硝子体、関節液、臍帯	1	0
コンドロイチン4-硫酸	D-グルクロン酸	N-アセチル-D-ガラクトサミン 4-硫酸	GlcUA	β1-3	GalNAc	骨、象牙質、軟骨	1	1
コンドロイチン6-硫酸	D-グルクロン酸	N-アセチル-D-ガラクトサミン 6-硫酸	GlcUA	β1-3	GalNAc		1	1
デルマタン硫酸	L-イズロン酸	N-アセチル-D-ガラクトサミン 4-硫酸	IdoA	β1-3	GalNAc	皮膚、動脈壁、腱、骨、象牙質	1	1
ケラタン硫酸	D-ガラクトース	N-アセチル-D-グルコサミン 6-硫酸	Gal	β1-4	GlcNAc	軟骨、椎間板、角膜	0	1
ヘパリン	L-イズロン酸 2-硫酸	N-スルホ-D-グルコサミン 6-硫酸	IdoA	α1-4	GlcNAc	小腸、筋肉、肺、脾、腱、肝、肥満細胞	1	3

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臨床関連

• ムコ多糖蓄積症(グリコサミノグリカン蓄積症)

「uronate」

　　[★]

ウロン酸

関

uronic acid

• uronic acid

「ウロン酸」

　　[★]

英

uronate, uronic acid

関

[[]]

「glucuronic acid」

　　[★]

グルクロン酸

関

glucuronate、glucuronic、sodium glucuronate

「tetragalacturonic acid hydroxymethylester」

　　[★]

テトラガラクト酸ヒドロキシメチルエステル

「iduronic acid」

　　[★]

• イズロン酸

関

iduronate、iduronic