WordNet
- any compound containing a chlorine atom
- any salt of hydrochloric acid (containing the chloride ion)
- liquid excretory product; "there was blood in his urine"; "the child had to make water" (同)piss, pee, piddle, weewee, water
PrepTutorEJDIC
- 塩化物
- 尿,小便
UpToDate Contents
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English Journal
- Perinatal growth restriction decreases diuretic action of furosemide in adult rats.
- Dubois BN1, Pearson J1, Mahmood T1, Nguyen D1, Thornburg K2, Cherala G3.Author information 1Department of Pharmacy Practice, College of Pharmacy, Oregon State University/Oregon Health & Science University, 3303, SW Bond Avenue, CH12C, Portland, OR 97239, USA.2Center for Developmental Health, Oregon Health & Science University, Portland, OR 97239, USA; Department of Obstetrics & Gynecology, School of Medicine, Oregon Health & Science University, Portland, OR 97239, USA.3Department of Pharmacy Practice, College of Pharmacy, Oregon State University/Oregon Health & Science University, 3303, SW Bond Avenue, CH12C, Portland, OR 97239, USA; Center for Developmental Health, Oregon Health & Science University, Portland, OR 97239, USA; Department of Obstetrics & Gynecology, School of Medicine, Oregon Health & Science University, Portland, OR 97239, USA. Electronic address: cheralag@ohsu.edu.AbstractPerinatal growth restriction programs higher risk for chronic disease during adulthood via morphological and physiological changes in organ systems. Perinatal growth restriction is highly correlated with a decreased nephron number, altered renal function and subsequent hypertension. We hypothesize that such renal maladaptations result in altered pharmacologic patterns for life. Maternal protein restriction during gestation and lactation was used to induce perinatal growth restriction in the current study. The diuretic response of furosemide (2mg/kg single i.p. dose) in perinatally growth restricted rats during adulthood was investigated. Diuresis, natriuresis and renal excretion of furosemide were significantly reduced relative to controls, indicative of decreased efficacy. While a modest 12% decrease in diuresis was observed in males, females experienced 26% reduction. It is important to note that the baseline urine output and natriuresis were similar between treatment groups. The in vitro renal and hepatic metabolism of furosemide, the in vivo urinary excretion of the metabolite, and the expression of renal drug transporters were unaltered. Creatinine clearance was significantly reduced by 15% and 19% in perinatally growth restricted male and female rats, respectively. Further evidence of renal insufficiency was suggested by decreased uric acid clearance. Renal protein expression of sodium-potassium-chloride cotransporter, a pharmacodynamic target, was unaltered. In summary, perinatal growth restriction could permanently imprint pharmacokinetic processes affecting drug response.
- European journal of pharmacology.Eur J Pharmacol.2014 Apr 5;728:39-47. doi: 10.1016/j.ejphar.2014.01.056. Epub 2014 Feb 5.
- Perinatal growth restriction programs higher risk for chronic disease during adulthood via morphological and physiological changes in organ systems. Perinatal growth restriction is highly correlated with a decreased nephron number, altered renal function and subsequent hypertension. We hypothesize t
- PMID 24508521
- The effect of centrifugation on three urine protein assays: benzethonium chloride, benzalkonium chloride and pyrogallol red.
- Sürer H, Ozgün T, Yilmaz FM, Yilmaz G.
- Clinical chemistry and laboratory medicine : CCLM / FESCC.Clin Chem Lab Med.2014 Apr 1;52(4):e71-3. doi: 10.1515/cclm-2013-0868.
- PMID 24280287
- Effects of fluid resuscitation with 0.9% saline versus a balanced electrolyte solution on acute kidney injury in a rat model of sepsis*.
- Zhou F1, Peng ZY, Bishop JV, Cove ME, Singbartl K, Kellum JA.Author information 11The CRISMA (Clinical Research, Investigation, and Systems Modeling of Acute Illness) Center, Department of Critical Care Medicine, University of Pittsburgh School of Medicine, Pittsburgh, PA. 2Department of Critical Care Medicine, Chinese People's Liberation Army General Hospital, Beijing, China. 3The Center for Critical Care Nephrology, Department of Critical Care Medicine, University of Pittsburgh School of Medicine, Pittsburgh, PA. 4Department of Cardiac Surgery, National University of Heart Center, Singapore. 5Department of Anesthesiology, Pennsylvania State University College of Medicine, Milton S. Hershey Medical Center, Hershey, PA.AbstractOBJECTIVE: To compare the acute effects of 0.9% saline versus a balanced electrolyte solution on acute kidney injury in a rat model of sepsis.
- Critical care medicine.Crit Care Med.2014 Apr;42(4):e270-8. doi: 10.1097/CCM.0000000000000145.
- OBJECTIVE: To compare the acute effects of 0.9% saline versus a balanced electrolyte solution on acute kidney injury in a rat model of sepsis.DESIGN: Controlled laboratory experiment.SETTING: University laboratory.SUBJECTS: Sixty adult, male Sprague-Dawley rats.INTERVENTIONS: We induced sepsis by ce
- PMID 24335444
Japanese Journal
- Reaction principle of the turbidimetric method for urine protein using benzalkonium chloride
- Suzuki Yuji
- International journal of analytical bio-science 2(4), 148-154, 2014-12
- NAID 40020305075
- Mechanisms Underlying Exercise-induced Diuresis Caused by 400-m Sprints
- SUZUKI Masato
- Advances in exercise and sports physiology 20(2), 35-44, 2014-06
- … The urine volume (UV); … levels of lactic acid (LA), pyruvic acid (PA), and other blood and urine solutes; … The levels of most urinary electrolytes (e.g. sodium and potassium) decreased only slightly, but the chloride (uCl) level decreased markedly. … In contrast, large amounts of LA and PA were excreted into the urine after the sprints. …
- NAID 110009830213
- 陽イオン性界面活性剤を用いる濁度法による尿蛋白質定量法の反応様式に関する検討
- 鈴木 優治
- 医学検査 63(6), 687-693, 2014
- 陽イオン性界面活性剤の塩化ベンゼトニウムを用いる濁度法による尿蛋白質定量法の反応様式について検討した.ヒト血清アルブミンおよびγ-グロブリンの濁度生成はそれぞれおおよそpH 5.5およびpH 6.0以上で起こった.この反応はpHに依存し,可逆的であり,生成した濁度は塩酸の添加でpHを低下させることにより減少した.濁度生成は負荷電蛋白質への正荷電した陽イオン性界面活性剤の結合により起こると考えられる …
- NAID 130005057063
Related Links
- Chloride - urine test Definition The urine chloride test measures the amount of chloride in urine. Alternative Names Urinary chloride How the Test is Performed After you provide a urine sample, it is tested in the lab. If needed ...
- This page includes the following topics and synonyms: Urine Chloride. ... These images are a real-time random sampling from a Google search on the term "Urine Chloride." Click on the image (or right click) to open the source ...
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