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1. 転移性大腸癌に対する全身化学療法：終了した臨床試験 systemic chemotherapy for metastatic colorectal cancer completed clinical trials
2. ビリルビン代謝 bilirubin metabolism
3. ビリルビン過剰産生によるジルベール症候群および非抱合型ビリルビン過剰産生 gilbert syndrome and unconjugated hyperbilirubinemia due to bilirubin overproduction
4. 成人における抗癌剤の投与 dosing of anticancer agents in adults
5. 黄疸または無症候性高ビリルビン血症の分類および原因 classification and causes of jaundice or asymptomatic hyperbilirubinemia

English Journal

Catechol-O-Methyltransferase and UDP-Glucuronosyltransferases in the Metabolism of Baicalein in Different Species.

Zhang R1, Cui Y1, Wang Y1,2, Tian X3, Zheng L4, Cong H4, Wu B4, Huo X1, Wang C1, Zhang B1, Wang X1,2, Yu Z5.
European journal of drug metabolism and pharmacokinetics.Eur J Drug Metab Pharmacokinet.2017 May 23. doi: 10.1007/s13318-017-0419-9. [Epub ahead of print]
PMID 28536775

Pharmacokinetic Interactions between Valproic Acid and Lorazepam (PIVOtAL Study): A Review of Site-Specific Practices.

Tang JY1, Kiang TKL2, Ensom MHH3.
The Canadian journal of hospital pharmacy.Can J Hosp Pharm.2017 May-Jun;70(3):171-178. Epub 2017 Jun 30.
PMID 28680170

Genetic Polymorphisms Affecting the Pharmacokinetics of Antiretroviral Drugs.

Calcagno A1, Cusato J2, D'Avolio A2, Bonora S2.
Clinical pharmacokinetics.Clin Pharmacokinet.2017 Apr;56(4):355-369. doi: 10.1007/s40262-016-0456-6.
PMID 27641153

Japanese Journal

Structure and function of uridine diphosphate glucuronosyltransferases

MEECH R.
Clin. Exp. Pharmacol. Physiol. 24, 907-915, 1997
NAID 80009962389

Separation and Purification of Uridine Diphosphate-Glucuronosyltransferases by Chromatofocusing on a High-Performance Liquid Chromatograph

高梨浩典,本間浩,松井道夫
Chemical & pharmaceutical bulletin 37(6), 1583-1586, 1989-06-25
… A rapid method for the separation and purification of uridine diphosphate-glucuronosyltransferases (GT) was developed with the use of chromatofocusing on a high-performance liquid chromatograph. …
NAID 110003627807

Related Links

Structure and function of uridine diphosphate ...

1. The uridine diphosphate (UDP)-glucuronosyltransferases (UGT) are a family of enzymes that catalyse the covalent addition of glucuronic acid to a wide range of lipophilic chemicals. They play a major role in the detoxification of many exogenous and endogenous compounds by generating products that are more polar and, thus, more readily ...

Uridine diphosphate glucuronosyltransferase 1A1 - National ...

Abstract. The role that the phase-II reaction, glucuronidation, plays in the biotransformation of endo and xenobiotics is discussed with particular emphasis given to the UGT1A1 isoenzyme. This individual isoenzyme is responsible for both the mono and di-glucuronidation of bilirubin together with the glucuronidation of a number of xenobiotics of ...

Uridine 5'-diphospho-glucronosyltrasferase: Its role in ...

Uridine 5'-diphospho (UDP)-glucuronosyltransferases (UGTs) are a superfamily of phase II enzymes which have roles in the conjugation of xenobiotics or endogenous compounds, including drugs and bilirubin, with glucuronic acid to