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出典(authority):フリー百科事典『ウィキペディア（Wikipedia）』「2016/02/15 20:17:33」(JST)

English Journal

Effect of luteolin on xanthine oxidase: Inhibition kinetics and interaction mechanism merging with docking simulation.

Yan J, Zhang G, Hu Y, Ma Y.SourceState Key Laboratory of Food Science and Technology, Nanchang University, No. 235 Nanjing East Road, Nanchang 330047, Jiangxi, China.
Food chemistry.Food Chem.2013 Dec 15;141(4):3766-73. doi: 10.1016/j.foodchem.2013.06.092. Epub 2013 Jun 28.
Xanthine oxidase (XO) catalyses hypoxanthine and xanthine to uric acid in human metabolism. Overproduction of uric acid will lead to hyperuricemia and finally cause gout and other diseases. Luteolin is one of the major components of celery and green peppers, its inhibitory activity on XO and their i
PMID 23993547

Hyperuricemia influences tryptophan metabolism via inhibition of multidrug resistance protein 4 (MRP4) and breast cancer resistance protein (BCRP).

Dankers AC, Mutsaers HA, Dijkman HB, van den Heuvel LP, Hoenderop JG, Sweep FC, Russel FG, Masereeuw R.SourceDepartment of Pharmacology and Toxicology, Radboud University Nijmegen Medical Centre, Nijmegen, The Netherlands.
Biochimica et biophysica acta.Biochim Biophys Acta.2013 Oct;1832(10):1715-22. doi: 10.1016/j.bbadis.2013.05.002. Epub 2013 May 9.
Hyperuricemia is related to a variety of pathologies, including chronic kidney disease (CKD). However, the pathophysiological mechanisms underlying disease development are not yet fully elucidated. Here, we studied the effect of hyperuricemia on tryptophan metabolism and the potential role herein of
PMID 23665398

Mediterranean diet and risk of hyperuricemia in elderly participants at high cardiovascular risk.

Guasch-Ferré M, Bulló M, Babio N, Martínez-González MA, Estruch R, Covas MI, Wärnberg J, Arós F, Lapetra J, Serra-Majem L, Basora J, Salas-Salvadó J.SourceHuman Nutrition Unit, Faculty of Medicine and Health Sciences, Universitat Rovira i Virgili, C/Sant Llorenç 21, 43201 Reus, Spain. jordi.salas@urv.cat.
The journals of gerontology. Series A, Biological sciences and medical sciences.J Gerontol A Biol Sci Med Sci.2013 Oct;68(10):1263-70. doi: 10.1093/gerona/glt028. Epub 2013 Apr 17.
BACKGROUND: A Mediterranean-type diet could play a role in decreasing serum uric acid concentrations due to its antioxidant and anti-inflammatory properties. The aim of this study was to evaluate whether better adherence to the Mediterranean diet (MeDiet) reduced or prevented the development of hype
PMID 23599357