WordNet

any of several cruciferous plants of the genus Brassica
leaves eaten as cooked greens (同)mustard greens, leaf mustard, Indian_mustard
pungent powder or paste prepared from ground mustard seeds (同)table mustard
a base containing nitrogen that is found in RNA (but not in DNA) and derived from pyrimidine; pairs with adenine (同)U

PrepTutorEJDIC

カラシ(アブラナ属の植物の総称) / マスタード,粉(練り)からし
ウラシル(核酸の加水分解で得られる針状結晶)

Wikipedia preview

出典(authority):フリー百科事典『ウィキペディア（Wikipedia）』「2014/08/05 20:28:06」(JST)

wiki en

Uramustine (INN) or uracil mustard is a chemotherapy drug which belongs to the class of alkylating agents. It is used in lymphatic malignancies such as non-Hodgkin's lymphoma. It works by damaging DNA, primarily in cancer cells that preferentially take up the uracil due to their need to make nucleic acids during their rapid cycles of cell division. The DNA damage leads to apoptosis of the affected cells. Bone marrow suppression and nausea are the main side effects.

Chemically it is a derivative of nitrogen mustard and uracil.

This antineoplastic or immunomodulatory drug article is a stub. You can help Wikipedia by expanding it.

UpToDate Contents

全文を閲覧するには購読必要です。 To read the full text you will need to subscribe.

1. 高IgM症候群 hyperimmunoglobulin m syndromes
2. 原発性の体液性免疫不全：概要 primary humoral immunodeficiencies an overview
3. 非プラチナ製剤ベースの癌化学療法の神経学的合併症の概要 overview of neurologic complications of non platinum cancer chemotherapy
4. BおよびTリンパ球の正常な発生 normal b and t lymphocyte development
5. 化学療法剤の腸管毒性 enterotoxicity of chemotherapeutic agents

English Journal

Cylindrospermopsin and microcystin-LR alter the growth, development and peroxidase enzyme activity of white mustard (Sinapis alba L.) seedlings, a comparative analysis.

M-Hamvas M, Máthé C, Vasas G, Jámbrik K, Papp M, Beyer D, Mészáros I, Borbély G.SourceDepartment of Botany, Faculty of Science and Technology, University of Debrecen, Eyetem tér 1 H-4010 Debrecen, Hungary.
Acta biologica Hungarica.Acta Biol Hung.2010;61 Suppl:35-48.
This work focuses on the comparative analysis of the effects of two cyanobacterial toxins of different chemical structure cylindrospermopsin (CYN) and microcystin-LR (MC-LR) on the white mustard (Sinapis alba L.) seedlings. Both cyanotoxins reduced significantly the fresh mass and the length of coty
PMID 21565763

[Study on the chemical constituents qf Spongilla Wagner].

Li YQ, Chai XY, Sun JF, Liu YH.SourceKey Laboratory of Marine Bio-resourses Sustainable utilization, South China Sea Institute of Oceanology, Chinese Academy of Sciences, Guangzhou 510240, China. autumn.li@163.com
Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials.Zhong Yao Cai.2010 Jan;33(1):60-1.
OBJECTIVE: To study the chemical constituents in the fresh marine sponge Spongilla Wagner.METHODS: Compounds were separated and purified through various chromatographic methods and their structures were identified by spectroscopic data.RESULTS: Seven compounds were isolated and identified as 4-hydro
PMID 20518307

Japanese Journal

Uracil Mustardに関する臨床的ならびに実験的研究

治療 48(1), 151-156, 1966-01
NAID 40018053521

悪性腫瘍患者に対するUracil Mustard(U8344)の臨床使用成績について

癌の臨床 11(13), 885-888, 1965-12
NAID 40017609285

悪性腫瘍患者に対するUracil Mustardの臨床使用成績について

県立がんセンター新潟病院医誌 5(1), 45-47, 1965-06
NAID 40017745651

Related Pictures

★リンクテーブル★

関連記事	「mustard」「uracil」

「mustard」

Uramustine
Systematic (IUPAC) name
	5-[bis(2-chloroethyl)amino]-1H-pyrimidine-2,4-dione
Clinical data
Legal status	?
Pharmacokinetic data
Protein binding	5%
Excretion	Renal
Identifiers
CAS number	66-75-1
ATC code	None
PubChem	CID 6194
DrugBank	DB00791
ChemSpider	5959
UNII	W7KQ46GJ8U
KEGG	D06265
ChEMBL	CHEMBL1488
Chemical data
Formula	C8H11Cl2N3O2
Mol. mass	252.097 g/mol
	SMILES O=C1C(\N(CCCl)CCCl)=C/NC(=O)N1;
	InChI InChI=1S/C8H11Cl2N3O2/c9-1-3-13(4-2-10)6-5-11-8(15)12-7(6)14/h5H,1-4H2,(H2,11,12,14,15) ; Key:IDPUKCWIGUEADI-UHFFFAOYSA-N ;
(what is this?) (verify)