ウラシルマスタード
WordNet
- any of several cruciferous plants of the genus Brassica
- leaves eaten as cooked greens (同)mustard greens, leaf mustard, Indian_mustard
- pungent powder or paste prepared from ground mustard seeds (同)table mustard
- a base containing nitrogen that is found in RNA (but not in DNA) and derived from pyrimidine; pairs with adenine (同)U
PrepTutorEJDIC
- カラシ(アブラナ属の植物の総称) / マスタード,粉(練り)からし
- ウラシル(核酸の加水分解で得られる針状結晶)
Wikipedia preview
出典(authority):フリー百科事典『ウィキペディア(Wikipedia)』「2014/08/05 20:28:06」(JST)
[Wiki en表示]
|
This article does not cite any references or sources. Please help improve this article by adding citations to reliable sources. Unsourced material may be challenged and removed. (December 2009) |
Uramustine
|
Systematic (IUPAC) name |
5-[bis(2-chloroethyl)amino]-1H-pyrimidine-2,4-dione |
Clinical data |
Legal status |
? |
Pharmacokinetic data |
Protein binding |
5% |
Excretion |
Renal |
Identifiers |
CAS number |
66-75-1 Y |
ATC code |
None |
PubChem |
CID 6194 |
DrugBank |
DB00791 |
ChemSpider |
5959 N |
UNII |
W7KQ46GJ8U N |
KEGG |
D06265 Y |
ChEMBL |
CHEMBL1488 N |
Chemical data |
Formula |
C8H11Cl2N3O2 |
Mol. mass |
252.097 g/mol |
SMILES
- O=C1C(\N(CCCl)CCCl)=C/NC(=O)N1
|
InChI
-
InChI=1S/C8H11Cl2N3O2/c9-1-3-13(4-2-10)6-5-11-8(15)12-7(6)14/h5H,1-4H2,(H2,11,12,14,15) N
Key:IDPUKCWIGUEADI-UHFFFAOYSA-N N
|
N (what is this?) (verify) |
Uramustine (INN) or uracil mustard is a chemotherapy drug which belongs to the class of alkylating agents. It is used in lymphatic malignancies such as non-Hodgkin's lymphoma. It works by damaging DNA, primarily in cancer cells that preferentially take up the uracil due to their need to make nucleic acids during their rapid cycles of cell division. The DNA damage leads to apoptosis of the affected cells. Bone marrow suppression and nausea are the main side effects.
Chemically it is a derivative of nitrogen mustard and uracil.
UpToDate Contents
全文を閲覧するには購読必要です。 To read the full text you will need to subscribe.
English Journal
- Cylindrospermopsin and microcystin-LR alter the growth, development and peroxidase enzyme activity of white mustard (Sinapis alba L.) seedlings, a comparative analysis.
- M-Hamvas M, Máthé C, Vasas G, Jámbrik K, Papp M, Beyer D, Mészáros I, Borbély G.SourceDepartment of Botany, Faculty of Science and Technology, University of Debrecen, Eyetem tér 1 H-4010 Debrecen, Hungary.
- Acta biologica Hungarica.Acta Biol Hung.2010;61 Suppl:35-48.
- This work focuses on the comparative analysis of the effects of two cyanobacterial toxins of different chemical structure cylindrospermopsin (CYN) and microcystin-LR (MC-LR) on the white mustard (Sinapis alba L.) seedlings. Both cyanotoxins reduced significantly the fresh mass and the length of coty
- PMID 21565763
- [Study on the chemical constituents qf Spongilla Wagner].
- Li YQ, Chai XY, Sun JF, Liu YH.SourceKey Laboratory of Marine Bio-resourses Sustainable utilization, South China Sea Institute of Oceanology, Chinese Academy of Sciences, Guangzhou 510240, China. autumn.li@163.com
- Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials.Zhong Yao Cai.2010 Jan;33(1):60-1.
- OBJECTIVE: To study the chemical constituents in the fresh marine sponge Spongilla Wagner.METHODS: Compounds were separated and purified through various chromatographic methods and their structures were identified by spectroscopic data.RESULTS: Seven compounds were isolated and identified as 4-hydro
- PMID 20518307
Japanese Journal
- Uracil Mustardに関する臨床的ならびに実験的研究
- 悪性腫瘍患者に対するUracil Mustard(U8344)の臨床使用成績について
- 悪性腫瘍患者に対するUracil Mustardの臨床使用成績について
Related Links
- uracil mustard - definition of uracil mustard by Medical dictionary http://medical-dictionary.thefreedictionary.com/uracil+mustard Printer Friendly Dictionary, Encyclopedia and Thesaurus - The Free Dictionary 7,260,192,083 visitors ...
- Uracil mustard 66-75-1 10 U237 (EPA List of Lists, 2012) Alternate Chemical Names What is this information? This section provides a listing of alternate names for this chemical, including trade names and synonyms. 5-(BIS(2 ...
Related Pictures
★リンクテーブル★
[★]
- 関
- Brassica juncea、Indian mustard
[★]
ウラシル, U, Ura