WordNet
- in an unfaithful undependable unreliable manner (同)undependably, unreliably
- not trustworthy; "an unfaithful reproduction"
- having sexual relations with someone other than your husband or wife, or your boyfriend or girlfriend; "her husband was unfaithful"
- not true to duty or obligation or promises; "an unfaithful lover"
PrepTutorEJDIC
- 不誠実な,誠意のない / 不貞の;(…に)不貞な《+to+名》 / 不正確な
English Journal
- Viewing Human DNA Polymerase β Faithfully and Unfaithfully Bypass an Oxidative Lesion by Time-Dependent Crystallography.
- Vyas R1, Reed AJ1, Tokarsky EJ1, Suo Z1.
- Journal of the American Chemical Society.J Am Chem Soc.2015 Apr 22;137(15):5225-30. doi: 10.1021/jacs.5b02109. Epub 2015 Apr 9.
- One common oxidative DNA lesion, 8-oxo-7,8-dihydro-2'-deoxyguanine (8-oxoG), is highly mutagenic in vivo due to its anti-conformation forming a Watson-Crick base pair with correct deoxycytidine 5'-triphosphate (dCTP) and its syn-conformation forming a Hoogsteen base pair with incorrect deoxyadenosin
- PMID 25825995
- DNA lesion alters global conformational dynamics of Y-family DNA polymerase during catalysis.
- Maxwell BA1, Xu C, Suo Z.
- The Journal of biological chemistry.J Biol Chem.2012 Apr 13;287(16):13040-7. doi: 10.1074/jbc.M112.345835. Epub 2012 Feb 23.
- A major product of oxidative damage to DNA, 8-oxo-7,8-dihydro-2'-deoxyguanine (8-oxoG), can lead to genomic mutations if it is bypassed unfaithfully by DNA polymerases in vivo. However, our pre-steady-state kinetic studies show that DNA polymerase IV (Dpo4), a prototype Y-family enzyme from Sulfolob
- PMID 22362779
- Telomeric allelic imbalance indicates defective DNA repair and sensitivity to DNA-damaging agents.
- Birkbak NJ1, Wang ZC, Kim JY, Eklund AC, Li Q, Tian R, Bowman-Colin C, Li Y, Greene-Colozzi A, Iglehart JD, Tung N, Ryan PD, Garber JE, Silver DP, Szallasi Z, Richardson AL.
- Cancer discovery.Cancer Discov.2012 Apr;2(4):366-75. doi: 10.1158/2159-8290.CD-11-0206. Epub 2012 Mar 22.
- DNA repair competency is one determinant of sensitivity to certain chemotherapy drugs, such as cisplatin. Cancer cells with intact DNA repair can avoid the accumulation of genome damage during growth and also can repair platinum-induced DNA damage. We sought genomic signatures indicative of defectiv
- PMID 22576213
Related Links
- 14 Feb 2010 ... A response to the monthly challenge at GSRForeverOnline.com : February is the month of romance, love and of course,Valentine's Day. With that train of though...
Related Pictures