潰瘍性出血

WordNet

a circumscribed inflammatory and often suppurating lesion on the skin or an internal mucous surface resulting in necrosis of tissue (同)ulceration

PrepTutorEJDIC

潰瘍
出血,(特に)大量出血 / 多量に出血する

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1. 出血性消化性潰瘍の治療の概要 overview of the treatment of bleeding peptic ulcers
2. 小児における上部消化管出血に対するアプローチ approach to upper gastrointestinal bleeding in children
3. 成人における急性上部消化管出血へのアプローチ approach to acute upper gastrointestinal bleeding in adults
4. 消化性潰瘍の合併症の概要 overview of the complications of peptic ulcer disease
5. 成人における上部消化管出血の主要な原因 major causes of upper gastrointestinal bleeding in adults

English Journal

Simultaneous quantification and peroxynitrite-scavenging activities of flavonoids in Polygonum aviculare L. herb.

Nugroho A1, Kim EJ2, Choi JS2, Park HJ3.Author information 1Department of Applied Plant Sciences, Graduate School, Sangji University, Wonju 220-702, Republic of Korea; Department of Agro-industrial Technology, Faculty of Agriculture, Lambung Mangkurat University, Banjarbaru 70712, Indonesia.2Department of Food Science and Nutrition, Pukyong National University, Busan 607-737, Republic of Korea.3Department of Pharmaceutical Engineering, Sangji University, Wonju 220-702, Republic of Korea. Electronic address: hjpark@sangji.ac.kr.AbstractThe plant Polygonum aviculare L. (Polygonaceae) is an annual herbaceous plant which is known to be beneficial for treating gastroduodenal ulcer, hypertension, diarrhea, hemorrhage, and hemorrhoids. Ten phenolic compounds, including nine flavonoids (myricetin, quercetin, kaempferol, myricitrin, desmanthin-1, isoquercitrin, quercitrin, avicularin, juglanin), and gallic acid were used for simultaneous HPLC quantification and peroxynitrite-scavenging assay. Simultaneous quantification of these substances were performed on five extracts (EtOH-, MeOH-, 70% MeOH-, 30% MeOH-, and H2O extracts) as well as on the three fractions (Et2O-, EtOAc-, and BuOH fractions), under the condition of a Capcell Pak C18 column (5μm, 250mm×4.6mm i.d.) and a gradient elution of 0.05% trifluoroacetic acid (TFA) and MeOHCH3CN (60:40). Of the three fractions, the EtOAc fraction displayed the highest content of flavonoids (sum, 208.9mg/g) with the strongest peroxynitrite-scavenging activity (IC50, 2.68μg/mL). The activities of the eight compounds (myricitrin, isoquercitrin, avicularin, quercitrin, myricetin, desmanthin-1, quercetin, and kaempferol) were comparable to that of the positive control (l-penicillamine; IC50: 1.03μg/mL). These results suggest that folkloric medicinal uses of P. aviculare are mainly attributed to flavonoids, such as particularly highly contained myricetin, myricitrin, and desmanthin-1.
Journal of pharmaceutical and biomedical analysis.J Pharm Biomed Anal.2014 Feb 15;89:93-8. doi: 10.1016/j.jpba.2013.10.037. Epub 2013 Nov 7.
The plant Polygonum aviculare L. (Polygonaceae) is an annual herbaceous plant which is known to be beneficial for treating gastroduodenal ulcer, hypertension, diarrhea, hemorrhage, and hemorrhoids. Ten phenolic compounds, including nine flavonoids (myricetin, quercetin, kaempferol, myricitrin, desma
PMID 24270289

Damage control surgery for abdominal emergencies.

Weber DG, Bendinelli C, Balogh ZJ.Author information Department of Traumatology, John Hunter Hospital and University of Newcastle, Newcastle, New South Wales, Australia.AbstractBACKGROUND: Damage control surgery is a management sequence initiated to reduce the risk of death in severely injured patients presenting with physiological derangement. Damage control principles have emerged as an approach in non-trauma abdominal emergencies in order to reduce mortality compared with primary definitive surgery.
The British journal of surgery.Br J Surg.2014 Jan;101(1):e109-18. doi: 10.1002/bjs.9360. Epub 2013 Nov 25.
BACKGROUND: Damage control surgery is a management sequence initiated to reduce the risk of death in severely injured patients presenting with physiological derangement. Damage control principles have emerged as an approach in non-trauma abdominal emergencies in order to reduce mortality compared wi
PMID 24273018

Temporal associations between low body condition, lameness and milk yield in a UK dairy herd.

Green LE, Huxley JN, Banks C, Green MJ.Author information School of Life Sciences, University of Warwick, Coventry CV4 7AL, England, United Kingdom. Electronic address: laura.green@warwick.ac.uk.AbstractPrevious work has hypothesised that cows in low body condition become lame. We tested this in a prospective longitudinal study. Body condition score (BCS), causes of lameness and milk yield were collected from a 600-cow herd over 44-months. Mixed effect binomial models and a continuous outcome model were used to investigate the associations between lameness, BCS and milk yield. In total, 14,320 risk periods were obtained from 1137 cows. There were 1510 lameness treatments: the most common causes of lameness were sole ulcer (SU) (39%), sole haemorrhage (SH) (13%), digital dermatitis (DD) (10%) and white line disease (WLD) (8%). These varied by year and year quarter. Body condition was scored at 60-day intervals. BCS ranged from 1 to 5 with a mean of 2.5, scores were higher in very early lactation but varied widely throughout lactation; approximately 45% of scores were <2.5. The key finding was that BCS<2.5 was associated with an increased risk of treatment for lameness in the following 0-2 months and >2-4 months for all causes of lameness and also specifically for SU/WLD lameness. BCS<2.5 was associated with an increased risk of treatment for SH in the following 0-2 months but not >2-4 months. There was no such association with DD. All lameness, SU/WLD, SH and DD were significantly more likely to occur in cows that had been lame previously, but the effect of BCS was present even when all repeat cases of lameness were excluded from the analysis. Milk yield was significantly higher and fell in the month before treatment in cows lame with SU/WLD but it was not significantly higher for cows that were treated for DD compared with non-lame cows. These findings support the hypothesis that low BCS contributes to the development of horn related claw lameness but not infectious claw diseases in dairy cows. One link between low BCS and lameness is a thin digital cushion which has been proposed as a trigger for claw horn disease. Cows with BCS 2 produced more milk than cows with BCS 2.5, however, this was only approximately 100kg difference in yield over a 305-day lactation. Given the increased risk of lameness in cows with BCS 2, the direct costs of lameness and the small variability in milk yield by BCS, preventing cows from falling to BCS<2.5 would improve cow welfare and be economically beneficial.
Preventive veterinary medicine.Prev Vet Med.2014 Jan 1;113(1):63-71. doi: 10.1016/j.prevetmed.2013.10.009. Epub 2013 Oct 18.
Previous work has hypothesised that cows in low body condition become lame. We tested this in a prospective longitudinal study. Body condition score (BCS), causes of lameness and milk yield were collected from a 600-cow herd over 44-months. Mixed effect binomial models and a continuous outcome model
PMID 24183787

Japanese Journal

下血を契機に発見された潰瘍を伴う多発小腸憩室症の1例

横田恭之,橋本真一,柴田大明,播磨郷子,坂井田功
山口医学 62(1), 39-42, 2013-02-01
… び空腸に多発する潰瘍と空腸Treiz靭帯近位に憩室内潰瘍が認められた.ジクロフェナクを常用されており,NSAIDs関連腸管粘膜障害が考えられた.憩室内には腸管内容物が貯留しやすく,高濃度のNSAIDsが憩室内に停滞したことが,憩室内に粗大な潰瘍を形成した要因と考えられた.小腸に憩室が認められる症例に対してはNSAIDsの投与は慎重に行う必要がある.We report a rare case of multiple duodenal diverticula associated with ulcer accompanied by …
NAID 120005246295

Explore the method of observing dynamic changes in microcirculation of rabbit's duodenal mucosal villi with a red color coordinate following brainstem hemorrhage

Jin Xuelong,Liang Bin,Wang Feifei,Zhang Zhiwen
Journal of brain science 39, 32-40, 2012-10-30
… Objective Those who suffer from brainstem hemorrhage complicated by stress ulcer hemorrhage have a high mortality. …
NAID 110009577642

Three Cases of Aggressive Natural Killer Cell Leukemia with a Lethal Hemorrhagic Complication

OKUNO Yutaka,TATETSU Hiro,NOSAKA Kisato,MITSUYA Hiroaki
Journal of clinical and experimental hematopathology 52(2), 101-106, 2012-10-01
… Although not treated with chemotherapy, Case 3 also suffered gross bleeding from an atypical duodenal ulcer and died from hemorrhagic shock 15 days after admission. …
NAID 10031120433