7型サイクリックヌクレオチドホスホジエステラーゼ
WordNet
- write by means of a keyboard with types; "type the acceptance letter, please" (同)typewrite
- a small metal block bearing a raised character on one end; produces a printed character when inked and pressed on paper; "he dropped a case of type, so they made him pick them up"
- (biology) the taxonomic group whose characteristics are used to define the next higher taxon
- a subdivision of a particular kind of thing; "what type of sculpture do you prefer?"
- all of the tokens of the same symbol; "the word `element contains five different types of character"
- printed characters; "small type is hard to read"
- identify as belonging to a certain type; "Such people can practically be typed" (同)typecast
- of a compound having atoms arranged in a ring structure
- recurring in cycles (同)cyclical
- conforming to the Carnot cycle
- forming a whorl or having parts arranged in a whorl; "cyclic petals"; "cyclic flowers"
- marked by repeated cycles
- a phosphoric ester of a nucleoside; the basic structural unit of nucleic acids (DNA or RNA) (同)base
- writing done with a typewriter (同)typewriting
PrepTutorEJDIC
- 〈C〉(…の)『型』,タイプ,類型,種類(kind)《+of+名》 / 〈C〉(その種類の特質を最もよく表している)『典型』,手本,模範《+of+名》 / 〈U〉《集合的に》活字;〈C〉(1個の)活字 / 〈U〉(印刷された)字体,活字 / 〈C〉(貨幣・メダルなどの)模様,図柄 / 〈C〉血液型(blood group) / …‘を'タイプに打つ / (…として)…‘を'分類する《+名+as+名(doing)》 / …‘の'型を決める / タイプライターを打つ
UpToDate Contents
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English Journal
- Role of cAMP-Phosphodiesterase 1C Signaling in Regulating Growth Factor Receptor Stability, Vascular Smooth Muscle Cell Growth, Migration, and Neointimal Hyperplasia.
- Cai Y1, Nagel DJ1, Zhou Q1, Cygnar KD1, Zhao H1, Li F1, Pi X1, Knight PA1, Yan C2.
- Circulation research.Circ Res.2015 Mar 27;116(7):1120-32. doi: 10.1161/CIRCRESAHA.116.304408. Epub 2015 Jan 21.
- RATIONALE: Neointimal hyperplasia characterized by abnormal accumulation of vascular smooth muscle cells (SMCs) is a hallmark of occlusive disorders such as atherosclerosis, postangioplasty restenosis, vein graft stenosis, and allograft vasculopathy. Cyclic nucleotides are vital in SMC proliferation
- PMID 25608528
- CHF6001 I: a novel highly potent and selective phosphodiesterase 4 inhibitor with robust anti-inflammatory activity and suitable for topical pulmonary administration.
- Moretto N1, Caruso P1, Bosco R1, Marchini G1, Pastore F1, Armani E1, Amari G1, Rizzi A1, Ghidini E1, De Fanti R1, Capaldi C1, Carzaniga L1, Hirsch E1, Buccellati C1, Sala A1, Carnini C1, Patacchini R1, Delcanale M1, Civelli M1, Villetti G1, Facchinetti F2.
- The Journal of pharmacology and experimental therapeutics.J Pharmacol Exp Ther.2015 Mar;352(3):559-67. doi: 10.1124/jpet.114.220541. Epub 2015 Jan 9.
- This study examined the pharmacologic characterization of CHF6001 [(S)-3,5-dichloro-4-(2-(3-(cyclopropylmethoxy)-4-(difluoromethoxy)phenyl)-2-(3-(cyclopropylmethoxy)-4-(methylsulfonamido)benzoyloxy)ethyl)pyridine 1-oxide], a novel phosphodiesterase (PDE)4 inhibitor designed for treating pulmonary in
- PMID 25576075
- An HD-domain phosphodiesterase mediates cooperative hydrolysis of c-di-AMP to affect bacterial growth and virulence.
- Huynh TN1, Luo S2, Pensinger D3, Sauer JD3, Tong L4, Woodward JJ5.
- Proceedings of the National Academy of Sciences of the United States of America.Proc Natl Acad Sci U S A.2015 Feb 17;112(7):E747-56. doi: 10.1073/pnas.1416485112. Epub 2015 Jan 12.
- The nucleotide cyclic di-3',5'- adenosine monophosphate (c-di-AMP) was recently identified as an essential and widespread second messenger in bacterial signaling. Among c-di-AMP-producing bacteria, altered nucleotide levels result in several physiological defects and attenuated virulence. Thus, a de
- PMID 25583510
Japanese Journal
- PDE4 and PDE5 regulate cyclic nucleotide contents and relaxing effects on carbachol-induced contraction in the bovine abomasum
- , , [他], ,
- Journal of Veterinary Medical Science 77(1), 15-19, 2015
- … The effects of various selective phosphodiesterase (PDE) inhibitors on carbachol (CCh)-induced contraction in the bovine abomasum were investigated. …
- NAID 130004781006
- PDE4 and PDE5 regulate cyclic nucleotide contents and relaxing effects on carbachol-induced contraction in the bovine abomasum
- , , , ,
- Journal of Veterinary Medical Science, 2014
- … The effects of various selective phosphodiesterase (PDE) inhibitors on carbachol (CCh)-induced contraction in the bovine abomasum were investigated. …
- NAID 130004699209
- Cytochemical and cytological properties of perineuronal oligodendrocytes in the mouse cortex
- Takasaki Chihiro,Yamasaki Miwako,Uchigashima Motokazu,Konno Kohtarou,Yanagawa Yuchio,Watanabe Masahiko
- European Journal of Neuroscience 32(8), 1326-1336, 2010-10
- … In this study, we identified perineuronal oligodendrocytes as 2',3'-cyclic nucleotide 3'-phosphodiesterase(CNP)-positive cells attaching to neuronal perikarya immunostained for microtubule-associated protein 2, and examined their cytochemical and cytological properties in the mouse cerebral cortex. …
- NAID 120003370661
Related Links
- Synthesis, structural analysis, and biological evaluation of thioxoquinazoline derivatives as phosphodiesterase 7 inhibitors. ... Cyclic Nucleotide Phosphodiesterases, Type 7/metabolism; Drug Design; Humans; Mice; Phosphodiesterase 4 ...
★リンクテーブル★
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- type 7 cyclic nucleotide phosphodiesterase
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- 関
- form、mode、pattern、type specimen、typed
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- 関
- annular、circular、cyclical、cyclicity、cyclo、periodic、periodicity
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- form、mode、pattern、type
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ホスホジエステラーゼ PDE