代謝回転数

WordNet

give numbers to; "You should number the pages of the thesis"
place a limit on the number of (同)keep_down
a concept of quantity involving zero and units; "every number has a unique position in the sequence"
the property possessed by a sum or total or indefinite quantity of units or individuals; "he had a number of chores to do"; "the number of parameters is small"; "the figure was about a thousand" (同)figure
a clothing measurement; "a number 13 shoe"
an item of merchandise offered for sale; "she preferred the black nylon number"; "this sweater is an all-wool number"
a numeral or string of numerals that is used for identification; "she refused to give them her Social Security number" (同)identification number
a select company of people; "I hope to become one of their number before I die"
the grammatical category for the forms of nouns and pronouns and verbs that are used depending on the number of entities involved (singular or dual or plural); "in English the subject and the verb must agree in number"
enumerate; "We must number the names of the great mathematicians" (同)list
so frightened as to be unable to move; stunned or paralyzed with terror; petrified; "too numb with fear to move"
make numb or insensitive; "The shock numbed her senses" (同)benumb, blunt, dull
a dish made by folding a piece of pastry over a filling

PrepTutorEJDIC

〈U〉〈C〉(数えて得られる)『数,数量』 / 〈C〉(概念としての)『数,数字』 / 〈C〉『番号』 / 〈C〉(演奏会や演劇の)番組,出し物;曲目 / 〈C〉(雑誌の)号 / 〈U〉(文法で)数(すう) / 《複数形で》数の上の優勢 / 《複数形で》算数 / 〈C〉《単数形で》《話》(商品としての)洋服の1点;商品,売り物 / 〈C〉《単随形で》《俗》女の子 / …‘を'数える / (…の中に,…として)…‘を'含める,加える《+『among』(『with, as』)+『名』》 / …‘に'番号をつける / …‘の'数となる / 《しばしば受動態で》…‘の'数を制限する / 総計(…に)なる《+『in』+『名』〈数〉》
麻痺(まひ)した,感覚を失った,しびれた / …‘の'感覚を失わせる,‘を'しびれさせる
〈C〉(車などの)転覆,転倒 / 〈U〉《しばしば a…》(一定期間内の)総取り引き高,売り上げ高 / 〈U〉《しばしば s…》(一定期間内の)補充労働者の総数(割合) / 〈U〉《しばしば a…》(一定期間内の)商品の回転率 / 〈C〉〈U〉(半円形形または三角形の)折り重ねパイ
数学,数学 / (人員などの)数の優勢 / 《米》《the~》=numbers game / 《古》詞句,韻文

Wikipedia preview

出典(authority):フリー百科事典『ウィキペディア（Wikipedia）』「2013/04/10 06:53:47」(JST)

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Turnover number has two related meanings:

In enzymology, turnover number (also termed k_cat) is defined as the maximum number of molecules of substrate that an enzyme can convert to product per catalytic site per unit of time and can be calculated as follows: k_cat = V_max/[E]_T (see Michaelis-Menten kinetics). For example, carbonic anhydrase has a turnover number of 400,000 to 600,000 s⁻¹, which means that each carbonic anhydrase molecule can produce up to 600,000 molecules of product (bicarbonate ions) per second.^[1]

In other chemical fields, such as organometallic catalysis, turnover number (abbreviated TON) is used with a slightly different meaning: the number of moles of substrate that a mole of catalyst can convert before becoming inactivated. An ideal catalyst would have an infinite turnover number in this sense, because it wouldn't ever be consumed, but in actual practice one often sees turnover numbers which go from 100 up to 40 million for Catalase. The term turnover frequency (abbreviated TOF) is used to refer to the turnover per unit time, as in enzymology. For most relevant industrial applications, the turnover frequency is in the range of 10⁻² - 10² s⁻¹ (enzymes 10³ - 10⁷ s⁻¹).^[1]

Turnover number of acetylcholinesterase

Acetylcholinesterase (AChE) may be one of the fastest enzymes. It hydrolyzes acetylcholine to choline and an acetate group. One of the earliest values of the turnover number was 3 x 10⁷ (molecules of acetylcholine) per minute per molecule of enzyme.^[2] A more recent value at 25°C, pH = 7.0, acetylcholine concentration of 2.5 x 10⁻³ M, was found to be 7.4 x 10⁵ min⁻¹.^[3]

There may be some 30 active centers per molecule.^[4] AChE is a serine hydrolase that reacts with acetylcholine at close to the diffusion-controlled rate.^[5]

References

^ Hagen J (2006). Industrial Catalysis: A Practical Approach. Weinheim, Germany: Wiley-VCH.
^ Rothenberg MA, Nachmansohn D (1947). "Studies on cholinesterase; purification of the enzyme from electric tissue by fractional ammonium sulfate precipitation.". J Biol Chem. 168 (1): 223–31. PMID 20291080.
^ Wilson IB, Harrison MA (Aug 1961). "Turnover number of acetylcholinesterase". J Biol Chem. 236 (8): 2292–5.
^ Berry WK (Oct 1951). "The turnover number of cholinesterase". Biochem J. 49 (5): 615–20. PMC 1197565. PMID 14886354.
^ Bazelyansky M, Robey E, Kirsch JF (1986). "Fractional diffusion-limited component of reactions catalyzed by acetylcholinesterase". Biochem. 25 (1): 125–30. doi:10.1021/bi00349a019. PMID 3954986.

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English Journal

A restricted level of PQBP1 is needed for the best longevity of Drosophila.

Tamura T, Sone M, Nakamura Y, Shimamura T, Imoto S, Miyano S, Okazawa H.SourceDepartment of Neuropathology, Medical Research Institute, Tokyo Medical and Dental University, Tokyo, Japan.
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PMID 22901698

Engineered proteins: redox properties and their applications.

Prabhulkar S, Tian H, Wang X, Zhu JJ, Li CZ.Source1 Nanobioengineering/Bioelectronics Laboratory, Department of Biomedical Engineering, Florida International University , Miami, Florida.
Antioxidants & redox signaling.Antioxid Redox Signal.2012 Dec 15;17(12):1796-822. doi: 10.1089/ars.2011.4001. Epub 2012 Jun 11.
Abstract Oxidoreductases and metalloproteins, representing more than one third of all known proteins, serve as significant catalysts for numerous biological processes that involve electron transfers such as photosynthesis, respiration, metabolism, and molecular signaling. The functional properties
PMID 22435347

Japanese Journal

揚名国司論 : 中世的身分表象の創出過程

渡辺滋
史學雜誌 123(1), 64-89, 2014-01-20
… Up through the 11th century, the number of available yomei appointments was limited to less than the number of qualified applicants and involved a continuous turnover rate of from several months to a year. …
NAID 110009798588

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倉林工
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… Based on fat histomorphometry, group 9D had a lower bone fat volume and number of fat cells in bone marrow compared with the other groups. … We conclude that female rats receiving testosterone within 9 days of birth, i.e. within the androgen-sensitive period, developed polycystic ovaries, high bone volume, low bone turnover, and lower fat content in the bone marrow. …
NAID 110009685697

Discovery and Exploitation of AZADO: The Highly Active Catalyst for Alcohol Oxidation

Iwabuchi Yoshiharu
Chemical and Pharmaceutical Bulletin 61(12), 1197-1213, 2013
… Stable organic nitroxyl radicals as represented by 2,2,6,6-tetramethylpiperidine-1-oxyl (TEMPO) (1) have been used extensively to catalyze the oxidation of a number of alcohol substrates employing environmentally benign co-oxidants such as bleach (NaOCl) or PhI(OAc)2. …
NAID 130003381786