tumor suppressor genes

出典: meddic

癌抑制遺伝子

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出典(authority):フリー百科事典『ウィキペディア(Wikipedia)』「2013/01/23 21:45:25」(JST)

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英文文献

  • IKBB tumor suppressive role in nasopharyngeal carcinoma via NF-κB-mediated signalling.
  • Phoon YP1, Cheung AK1,2, Cheung FM3,4, Chan KF5, Wong S6, Wong BW1, Tung SY3,7, Yau CC3,8, Ng WT3,9, Lung ML1,2,3.
  • International journal of cancer. Journal international du cancer.Int J Cancer.2016 Jan 1;138(1):160-70. doi: 10.1002/ijc.29702. Epub 2015 Aug 10.
  • Tumor suppressor genes (TSGs) play a prominent role in cancer and are important in the development of nasopharyngeal carcinoma (NPC), which is endemic in Southern China as well as Southeast Asia. Apart from TSGs, aberrant signalling pathways are also commonly associated with tumor progression. Unsur
  • PMID 26227166
  • Histone methylation modifiers in cellular signaling pathways.
  • Alam H1, Gu B1, Lee MG2,3,4.
  • Cellular and molecular life sciences : CMLS.Cell Mol Life Sci.2015 Dec;72(23):4577-92. doi: 10.1007/s00018-015-2023-y. Epub 2015 Aug 25.
  • Histone methyltransferases and demethylases epigenetically regulate gene expression by modifying histone methylation status in numerous cellular processes, including cell differentiation and proliferation. These modifiers also control methylation levels of various non-histone proteins, such as effec
  • PMID 26305020
  • Transcriptional dysregulation of the deleted in colorectal carcinoma gene in multiple myeloma and monoclonal gammopathy of undetermined significance.
  • Nagoshi H1, Taki T2, Chinen Y1, Tatekawa S1, Tsukamoto T1, Maegawa S1, Yamamoto-Sugitani M1, Tsutsumi Y1,3, Kobayashi T1, Matsumoto Y1, Horiike S1, Okuno Y4, Fujiwara S4, Hata H5, Kuroda J1, Taniwaki M1,2.
  • Genes, chromosomes & cancer.Genes Chromosomes Cancer.2015 Dec;54(12):788-95. doi: 10.1002/gcc.22290. Epub 2015 Sep 22.
  • The deleted in colorectal carcinoma (DCC) gene at 18q21 encodes a netrin-1 receptor, a tumor suppressor that prevents cell growth. While allele loss or decreased expression of DCC has been associated with the progression of solid tumors and hematologic malignancies, including leukemias and malignant
  • PMID 26390996

和文文献

  • Context-dependent activation of Wnt signaling by tumor suppressor RUNX3 in gastric cancer cells
  • Ju Xiaoli,Ishikawa Tomo-o,Naka Kazuhito,Ito Kosei,Ito Yoshiaki,Oshima Masanobu
  • Cancer Science 105(4), 418-424, 2014-04
  • … RUNX3 is a tumor suppressor for a variety of cancers. … Moreover, the ChIP analyses revealed that TCF4, β-catenin and RUNX3 bind the promoter region of the Wnt target genes, Axin2 and c-Myc, and the occupancy of TCF4 and β-catenin in these promoter regions is increased by the RUNX3 expression. …
  • NAID 120005438970
  • Context-dependent activation of Wnt signaling by tumor suppressor RUNX3 in gastric cancer cells
  • Ju Xiaoli,Ishikawa Tomo-o,Naka Kazuhito,Ito Kosei,Ito Yoshiaki,Oshima Masanobu
  • Cancer Science 105(4), 418-424, 2014-04
  • … RUNX3 is a tumor suppressor for a variety of cancers. … Moreover, the ChIP analyses revealed that TCF4, β-catenin and RUNX3 bind the promoter region of the Wnt target genes, Axin2 and c-Myc, and the occupancy of TCF4 and β-catenin in these promoter regions is increased by the RUNX3 expression. …
  • NAID 120005418485
  • BOB.1-positive Classical Hodgkin's Lymphoma Carries Hypermethylation of Its Promoter as Epigenetic Marker of Gene-silencing Memory
  • Watanabe Takafumi,Kitazawa Riko,Mizuno Yosuke,Kuwahara Natsumi,Ito Chizu,Sugita Atsuro,Haraguchi Ryuma,Kitazawa Sohei
  • ACTA HISTOCHEMICA ET CYTOCHEMICA 47(3), 125-131, 2014
  • … When some tumor-suppressor gene products have lost their biological function, impact or significance of derepression of such genes may be little. …
  • NAID 130004137836

関連リンク

The activation of cellular oncogenes represents only one of two distinct types of genetic alterations involved in tumor development; the other is inactivation of tumor suppressor genes. Oncogenes drive abnormal cell proliferation as a ...
Tumor Suppressor Genes: Guardians of Our Cells Fact Sheet #06, December 1997 Tumor suppressor genes play a critical role in regulating when cells are allowed to divide and increase in number. When DNA damage is detected in a ...

関連画像

Image from: Tumor Suppressor Genes ) - Tumor Suppressor Genes and Oncogenesoncogenes and tumor suppressor genesTumor Suppressor Genes | Oncogenes and oncogenes and tumor suppressor genesTumor Suppressor Genes and Oncogenes


★リンクテーブル★
リンク元癌抑制遺伝子
関連記事suppress」「suppressor」「gene」「tumor」「gen

癌抑制遺伝子」

  [★]

tumor suppressor gene, tumor suppressor genes, suppressor oncogene, anti-oncogene
がん抑制遺伝子腫瘍抑制遺伝子
癌遺伝子



suppress」

  [★]

  • v.
abrogateabrogationarrestcurbdepressdepressioninhibitinhibitionrestrainrestraintsubduesuppression

WordNet   license wordnet

「to put down by force or authority; "suppress a nascent uprising"; "stamp down on littering"; "conquer one''s desires"」
stamp down, inhibit, subdue, conquer, curb

WordNet   license wordnet

「reduce the incidence or severity of or stop; "suppress a yawn"; "this drug can suppress the hemorrhage"」

WordNet   license wordnet

「put out of one''s consciousness」
repress

PrepTutorEJDIC   license prepejdic

「〈反乱など〉‘を'『鎮圧する』…,‘の'活動を押える / 〈感情・欲望など〉‘を'『抑制する』,抑える / …‘の'発表を禁止する,伏せる」

suppressor」

  [★]

inhibitory factorrepressor

WordNet   license wordnet

「an electrical device for suppressing unwanted currents」
suppresser

WordNet   license wordnet

「someone who suppresses; "dictators are suppressors of free speech"」
suppresser

WordNet   license wordnet

「a gene that suppresses the phenotypic expression of another gene (especially of a mutant gene)」
suppresser, suppressor gene, suppresser gene

PrepTutorEJDIC   license prepejdic

「抑圧する人,鎮圧者 / (ラジオ・テレビの)妨害電波(混信)防止装置」


gene」

  [★] 遺伝子

WordNet   license wordnet

「(genetics) a segment of DNA that is involved in producing a polypeptide chain; it can include regions preceding and following the coding DNA as well as introns between the exons; it is considered a unit of heredity; "genes were formerly called factors"」
cistron, factor

PrepTutorEJDIC   license prepejdic

「遺伝子」

tumor」

  [★]

  • n.


WordNet   license wordnet

「an abnormal new mass of tissue that serves no purpose」
tumour, neoplasm


gen」

  [★]

WordNet   license wordnet

「informal term for information; "give me the gen on your new line of computers"」




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