同: 腫瘍濃染像

WordNet

(microscopy) a dye or other coloring material that is used in microscopy to make structures visible
color for microscopic study; "The laboratory worker dyed the specimen"
color with a liquid dye or tint; "Stain this table a beautiful walnut color"; "people knew how to stain glass a beautiful blue in the middle ages"
produce or leave stains; "Red wine stains the table cloth"
a soiled or discolored appearance; "the wine left a dark stain" (同)discoloration, discolouration
marked or dyed or discolored with foreign matter; "a badly stained tablecloth"; "tear-stained cheeks"
having a coating of stain or varnish (同)varnished
the act of spotting or staining something (同)spotting, maculation
(histology) the use of a dye to color specimens for microscopic study
an abnormal new mass of tissue that serves no purpose (同)tumour, neoplasm

PrepTutorEJDIC

(…で)…‘を'『汚す』,‘に'しみをつける《+『名』+『with』+『名』》 / 〈ガラス・木材・布など〉‘に'『着色する』 / (…で)〈人格・名声など〉‘を'汚す,‘に'傷をつける《+『名』+『with』+『名』》 / 汚れる,しみがつく / 〈C〉〈U〉(…についた)『しみ』,汚れ《+『on』+『名』》 / 〈U〉〈C〉着色剤,染料 / 〈C〉(人格・名声などに対する)汚点,傷《+『on』(『upon』)+『名』》

UpToDate Contents

全文を閲覧するには購読必要です。 To read the full text you will need to subscribe.

1. まれな脳腫瘍 uncommon brain tumors
2. 精巣腫瘍の解剖学および病理 anatomy and pathology of testicular tumors
3. 軟部組織肉腫の臨床所見、病理組織学的検査、診断的評価、および病期分類 clinical presentation histopathology diagnostic evaluation and staging of soft tissue sarcoma
4. 転移性の胃腸膵管系神経内分泌腫瘍：腫瘍増殖およびホルモン過剰分泌による症状を管理するための局所治療の選択肢 metastatic gastroenteropancreatic neuroendocrine tumors local options to control tumor growth and symptoms of hormone hypersecretion
5. 気管支神経内分泌（カルチノイド）腫瘍：疫学、危険因子、分類、組織学的検査、診断、および病期分類 bronchial neuroendocrine carcinoid tumors epidemiology risk factors classification histology diagnosis and staging

English Journal

Heterozygous inactivation of the Nf1 gene in myeloid cells enhances neointima formation via a rosuvastatin-sensitive cellular pathway.

Stansfield BK, Bessler WK, Mali R, Mund JA, Downing B, Li F, Sarchet KN, Distasi MR, Conway SJ, Kapur R, Ingram DA Jr.AbstractMutations in the NF1 tumor suppressor gene cause Neurofibromatosis type 1 (NF1). Neurofibromin, the protein product of NF1, functions as a negative regulator of Ras activity. Some NF1 patients develop cardiovascular disease, which represents an underrecognized disease complication and contributes to excess morbidity and mortality. Specifically, NF1 patients develop arterial occlusion resulting in tissue ischemia and sudden death. Murine studies demonstrate that heterozygous inactivation of Nf1 (Nf1(+/-)) in bone marrow cells enhances neointima formation following arterial injury. Macrophages infiltrate Nf1(+/-) neointimas, and NF1 patients have increased circulating inflammatory monocytes in their peripheral blood. Therefore, we tested the hypothesis that heterozygous inactivation of Nf1 in myeloid cells is sufficient for neointima formation. Specific ablation of a single copy of the Nf1 gene in myeloid cells alone mobilizes a discrete pro-inflammatory murine monocyte population via a cell autonomous and gene-dosage dependent mechanism. Furthermore, lineage-restricted heterozygous inactivation of Nf1 in myeloid cells is sufficient to reproduce the enhanced neointima formation observed in Nf1(+/-) mice when compared with wild-type controls, and homozygous inactivation of Nf1 in myeloid cells amplified the degree of arterial stenosis after arterial injury. Treatment of Nf1(+/-) mice with rosuvastatin, a stain with anti-inflammatory properties, significantly reduced neointima formation when compared with control. These studies identify neurofibromin-deficient myeloid cells as critical cellular effectors of Nf1(+/-) neointima formation and propose a potential therapeutic for NF1 cardiovascular disease.
Human molecular genetics.Hum Mol Genet.2013 Mar 1;22(5):977-88. doi: 10.1093/hmg/dds502. Epub 2012 Nov 29.
Mutations in the NF1 tumor suppressor gene cause Neurofibromatosis type 1 (NF1). Neurofibromin, the protein product of NF1, functions as a negative regulator of Ras activity. Some NF1 patients develop cardiovascular disease, which represents an underrecognized disease complication and contributes to
PMID 23197650

14-3-3 Sigma is a Useful Immunohistochemical Marker for Diagnosing Ovarian Granulosa Cell Tumors and Steroid Cell Tumors.

Chen L, Yang B.SourceDepartment of Laboratory Medicine and Pathology (L.C.), The Mayo Clinic, Scottsdale, Arizona Department of Anatomic Pathology (B.Y.), The Cleveland Clinic, Cleveland, Ohio.
International journal of gynecological pathology : official journal of the International Society of Gynecological Pathologists.Int J Gynecol Pathol.2013 Mar;32(2):156-62. doi: 10.1097/PGP.0b013e31825a0353.
The distinction of ovarian granulosa cell tumors (GCTs) from other sex-cord stromal tumors may be difficult histologically. Many immunohistochemical markers have been studied for this differential diagnosis, but the available markers are not entirely specific for ovarian GCT. 14-3-3 sigma has been s
PMID 23370648

A novel adipocytokine visfatin protects against H(2)O(2) -induced myocardial apoptosis: a missing link between obesity and cardiovascular disease.

Xiao J, Sun B, Li M, Wu Y, Sun XB.SourceResearch Center for Pharmacology and Toxicology, Institute of Medicinal Plant Development, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, PR China.
Journal of cellular physiology.J Cell Physiol.2013 Mar;228(3):495-501. doi: 10.1002/jcp.24257.
Fat accumulation in obese individuals worsens the clinical outcomes of cardiovascular disease (CVD). Paradoxically, increased circulating adipocytokines secreted from visceral fat may confer cardioprotective effects. Visfatin, a novel adipocytokine, has anti-diabetic, anti-tumor, and pro-inflammator
PMID 23065734