尿細管再吸収

WordNet

constituting a tube; having hollow tubes (as for the passage of fluids) (同)cannular, tubelike, tube-shaped, vasiform

PrepTutorEJDIC

管状の,管から成る

Wikipedia preview

出典(authority):フリー百科事典『ウィキペディア（Wikipedia）』「2016/01/22 13:06:45」(JST)

wiki en

In physiology, reabsorption or tubular reabsorption is the method of [contraception from the male tubule of the nephron into the peritubular capillaries from the urine into the blood. It is termed "reabsorption" because the fluid and other substances that are reabsorbed from the bloodstream through the glomerulus into Bowman's capsule, which leads to the peritubular capillaries. This happens as a result of sodium transport from the lumen into the blood by the Na+/K+ ATPase in the basolateral membrane of the epithelial cells. Thus, the glomerular filtrate becomes more concentrated, which is one of the steps in forming urine. In this way, many useful solutes (primarily glucose and amino acids), salts and water that have passed in the proximal convoluted tubule through Bowman's capsule, return in the circulation. These solutes are reabsorbed isotonically, in that the osmotic potential of the fluid leaving the proximal convoluted tubule is the same as that of the initial glomerular filtrate. However, glucose, amino acids, inorganic phosphate, and some other solutes are reabsorbed via secondary active transport through cotransport channels driven by the sodium gradient out of the nephron.

Renin Angiotensin System:

1. The kidneys sense low blood pressure.

2. Release renin into the blood.

3. Renin causes production of Angiotensin I.

4. Angiotensin Converting Enzyme (ACE) converts Angiotensin I to Angiotensin II.

5. Angiotensin II stimulates the release of Aldosterone, ADH, and thirst.

6. Aldosterone causes kidneys to reabsorb sodium. ADH increases the uptake of water.

7. Water follows sodium.

8. As blood volume increases, pressure also increases.

This anatomy article is a stub. You can help Wikipedia by expanding it.

UpToDate Contents

全文を閲覧するには購読必要です。 To read the full text you will need to subscribe.

1. Etiology and diagnosis of distal (type 1) and proximal (type 2) renal tubular acidosis
2. 尿細管性アシドーシスにおける腎結石症 nephrolithiasis in renal tubular acidosis
3. 腎尿細管性アシドーシスの概要と病態生理、およびカリウムバランスへの影響 overview and pathophysiology of renal tubular acidosis and the effect on potassium balance
4. 急性尿細管壊死後の腎臓および患者の転帰 renal and patient outcomes after acute tubular necrosis
5. 急性腎障害（急性腎不全）における腎前性疾患および急性尿細管壊死の病因および診断 etiology and diagnosis of prerenal disease and acute tubular necrosis in acute kidney injury acute renal failure

English Journal

A unifying mechanism for WNK kinase regulation of sodium-chloride cotransporter.

Huang CL1, Cheng CJ2.
Pflügers Archiv : European journal of physiology.Pflugers Arch.2015 Nov;467(11):2235-41. doi: 10.1007/s00424-015-1708-2. Epub 2015 Apr 24.
Mammalian with-no-lysine [K] (WNK) kinases are a family of four serine-threonine protein kinases, WNK1-4. Mutations of WNK1 and WNK4 in humans cause pseudohypoaldosteronism type II (PHA2), an autosomal-dominant disease characterized by hypertension and hyperkalemia. Increased Na(+) reabsorption thro
PMID 25904388

Development of A Cell-Based Assay to Identify Small Molecule Inhibitors of FGF23 Signaling.

Diener S1, Schorpp K2, Strom TM1,3, Hadian K2, Lorenz-Depiereux B1.
Assay and drug development technologies.Assay Drug Dev Technol.2015 Oct;13(8):476-87. doi: 10.1089/adt.2015.653.
Fibroblast growth factor 23 (FGF23) is a bone-derived endocrine key regulator of phosphate homeostasis. It inhibits renal tubular phosphate reabsorption by activating receptor complexes composed of FGF receptor 1c (FGFR1c) and the co-receptor Klotho. As a major signaling pathway mitogen-activated pr
PMID 26461432

Heat stress, dehydration, and kidney function in sugarcane cutters in El Salvador - A cross-shift study of workers at risk of Mesoamerican nephropathy.

García-Trabanino R1, Jarquín E2, Wesseling C3, Johnson RJ4, González-Quiroz M5, Weiss I6, Glaser J7, José Vindell J8, Stockfelt L9, Roncal C10, Harra T11, Barregard L12.
Environmental research.Environ Res.2015 Oct;142:746-55. doi: 10.1016/j.envres.2015.07.007. Epub 2015 Jul 23.
BACKGROUND: An epidemic of progressive kidney failure afflicts sugarcane workers in Central America. Repeated high-intensity work in hot environments is a possible cause.OBJECTIVES: To assess heat stress, dehydration, biomarkers of renal function and their possible associations. A secondary aim was
PMID 26209462