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出典(authority):フリー百科事典『ウィキペディア(Wikipedia)』「2012/09/15 12:52:30」(JST)

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  • Evaluating 5-nitrofurans as trypanocidal agents.
  • Bot C, Hall BS, Alvarez G, Di Maio R, González M, Cerecetto H, Wilkinson SR.SourceQueen Mary Pre-Clinical Drug Discovery Group, School of Biological and Chemical Sciences, Queen Mary University of London, London, United Kingdom.
  • Antimicrobial agents and chemotherapy.Antimicrob Agents Chemother.2013 Apr;57(4):1638-47. doi: 10.1128/AAC.02046-12. Epub 2013 Jan 18.
  • The nitroheterocycle nifurtimox, as part of a nifurtimox-eflornithine combination therapy, represents one of a limited number of treatments targeting Trypanosoma brucei, the causative agent of human African trypanosomiasis. The mode of action of this prodrug involves an initial activation reaction c
  • PMID 23335745
  • Mechanisms of complement lectin pathway activation and resistance by trypanosomatid parasites.
  • Cestari I, Evans-Osses I, Schlapbach LJ, de Messias-Reason I, Ramirez MI.SourceSeattle Biomedical Research Institute, Seattle, WA 98109, USA.
  • Molecular immunology.Mol Immunol.2013 Apr;53(4):328-34. doi: 10.1016/j.molimm.2012.08.015. Epub 2012 Oct 9.
  • Studies in the past decade have demonstrated a crucial role for the complement lectin pathway in host defence against protozoan microbes. Recognition of pathogen surface molecules by mannan-binding lectin and ficolins revealed new mechanisms of innate immune defence and a diversity of parasite strat
  • PMID 23063472
  • PCR based diagnosis of trypanosomiasis exploring invariant surface glycoprotein (ISG) 75 gene.
  • Rudramurthy GR, Sengupta PP, Balamurugan V, Prabhudas K, Rahman H.SourceProject Directorate on Animal Disease Monitoring and Surveillance, Hebbal, Bengaluru 560024, Karnataka, India.
  • Veterinary parasitology.Vet Parasitol.2013 Mar 31;193(1-3):47-58. doi: 10.1016/j.vetpar.2012.11.045. Epub 2012 Dec 11.
  • The invariant surface glycoprotein (ISG-75) gene of Trypanosoma evansi buffalo isolate from Karnataka state in India was sequenced and analyzed to elucidate its relationship with other isolates/species. The sequenced ISG-75 gene was also explored to device a polymerase chain reaction (PCR) strategy
  • PMID 23305969


  • アフリカ睡眠病治療薬の候補化合物と標的タンパク質との複合体構造
  • 志波 智生,高橋 元,原田 繁春 [他],斎本 博之,城戸 康年,稲岡 ダニエル健,北 潔
  • 日本結晶学会誌 55(4), 254-259, 2013
  • … We determined the first crystal structures of the trypanosomal alternative oxidase in the absence and presence of ascofuranone and its derivatives, which are drug candidates for African trypanosomiasis. …
  • NAID 130003373914
  • The use of Loop-mediated Isothermal Amplification (LAMP) to detect the re-emerging Human African Trypanosomiasis (HAT) in the Luangwa and Zambezi valleys
  • Namangala Boniface,Hachaambwa Lottie,Kajino Kiichi,Mweene Aaron S.,Hayashida Kyouko,Simuunza Martin,Simukoko Humphrey,Choongo Kennedy,Chansa Pamela,Lakhi Shabir,Moonga Ladslav,Chota Amos,Ndebe Joseph,Nsakashalo-Senkwe Mutale,Chizema Elizabeth,Kasonka Lackson,Sugimoto Chihiro
  • Parasites & Vectors 5, 282, 2012-12-04
  • Background: Loop-mediated isothermal amplification (LAMP) is a novel strategy which amplifies DNA with high sensitivity and rapidity under isothermal conditions. In the present study, the performance …
  • NAID 120005183188
  • 寄生性原虫類のグリコシルホスファチジルイノシトール
  • TSAI Yu-Hsuan,GRUBE Maurice,SEEBERGER Peter H.,VARON SILVA Daniel
  • Trends in glycoscience and glycotechnology 24(138), 231-243, 2012-11-30
  • NAID 10031146676


Trypanosomiasis or trypanosomosis is the name of several diseases in vertebrates caused by parasitic protozoan trypanosomes of the genus Trypanosoma. Approximately 500000 men, women, and children in 36 countries of sub-Saharan ...


Trypanosomiasis african Essentials -Amerikaanse trypanosomiasis (bron: CDCTrypanosomiasis : Definition, Causes TrypanosomiasisAfrican trypanosomiasisHuman African Trypanosomiasis (HAT

拡張検索East African trypanosomiasis」「West African trypanosomiasis」「bovine trypanosomiasis







East African trypanosomiasis」

  [★] 東アフリカトリパノソーマ症

West African trypanosomiasis」

  [★] 西アフリカトリパノソーマ症

bovine trypanosomiasis」