English Journal

Pupillary function test in rat: Establishment of imaging setup and pharmacological validation within modified Irwin test.

Himmel HM, Eriksson Faelker TM.
Journal of pharmacological and toxicological methods. 2019 May;()106588.
Pupillary function is a sensitive pharmacological readout in humans, but drug effects are not well characterized in rodents. Hence improved methods are needed for quantifying pupillary responses in conscious albino rodents. A novel camera-based pupillary imaging method was developed for conscious ra
PMID 31146024

[Study on analgesic effect and mechanism of cinobufagin on rats with bone cancer pain].

Systemic exposure to intracameral vs topical mydriatic agents: in cataract surgery.

Guell J, Behndig A, Pleyer U, Jaulerry S, Rozot P, Pisella PJ, Robert PY, Lanzl I, Pourjavan S, Aguiar C, Fernandez J, Grabner G, Mencucci R, Chiambaretta F, Labetoulle M.
Clinical ophthalmology (Auckland, N.Z.). 2019 ;13()811-819.
The objective of this study was to compare systemic exposure to tropicamide/phenylephrine following intracameral or topical administration before cataract surgery. Mydriatics exposure was calculated in patients randomized to intracameral fixed combination of mydriatics and anesthetic ([ICMA]: tropic
PMID 31118559

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