trisomy 5q

WordNet

chrosomal abnormality in which there is one more than the normal number of chromosomes in a cell

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1. 骨髄異形成症候群における細胞遺伝学および分子遺伝学 cytogenetics and molecular genetics of myelodysplastic syndromes
2. 急性骨髄性白血病における細胞遺伝学 cytogenetics in acute myeloid leukemia
3. 骨髄異形成症候群の臨床症状および診断 clinical manifestations and diagnosis of the myelodysplastic syndromes
4. 血液悪性腫瘍における細胞遺伝子解析の一般的側面 general aspects of cytogenetic analysis in hematologic malignancies
5. 高リスクまたは極めて高リスクの骨髄異形成症候群の治療 treatment of high or very high risk myelodysplastic syndromes

[Establishment of Primary Adult MDS Nested Case-Control Study Cohort and Study of Risk Factors Associated with MDS Evolution to Leukemia].

Ma Y1, Chen BB1, Wang XQ1, Xu XP2, Lin GW1.
Zhongguo shi yan xue ye xue za zhi / Zhongguo bing li sheng li xue hui = Journal of experimental hematology / Chinese Association of Pathophysiology.Zhongguo Shi Yan Xue Ye Xue Za Zhi.2015 Dec;23(6):1638-46. doi: 10.7534/j.issn.1009-2137.2015.06.021.
OBJECTIVE: To establish a nested case-control study cohort in myelodysplastic syndrome (MDS) patients and investigate the clinical characteristics, WHO subtype and risk factors associated with MDS evolution to leukemia of this cohort.METHODS: All patients, ≥18 years of age, provided by 24 Shanghai
PMID 26708886

Pellagatti A1, Boultwood J1.
European journal of haematology.Eur J Haematol.2015 Jul;95(1):3-15. doi: 10.1111/ejh.12515. Epub 2015 Feb 20.
Recent studies have greatly illuminated the genomic landscape of the myelodysplastic syndromes (MDS), and the pace of discovery is accelerating. The most common mutations found in MDS occur in genes involved in RNA splicing (including SF3B1, SRSF2, U2AF1, and ZRSR2) and epigenetic modification (incl
PMID 25645650

Transformed aggressive γδ-variant T-cell large granular lymphocytic leukemia with acquired copy neutral loss of heterozygosity at 17q11.2q25.3 and additional aberrations.

Zhang L1, Ramchandren R, Papenhausen P, Loughran TP, Sokol L.
European journal of haematology.Eur J Haematol.2014 Sep;93(3):260-4. doi: 10.1111/ejh.12313. Epub 2014 Apr 7.
T-cell large granular lymphocytic leukemia (T-LGLL) is a rare indolent lymphoproliferative disorder characterized by cytopenias, splenomegaly, and various degrees of T-cell lymphocytosis, due to a clonal expansion of CD8-positive cytotoxic T-cells. Phenotypic variants of T-LGLL include CD4(+) /CD8(-
PMID 24635703

A Case of Severe Mental and Developmental Retardation Associated with 14q Terminal Monosomy/5q Terminal Trisomy

Acute megakaryoblastic leukaemia (AMKL) in children: a comparison of AMKL with and without Down syndrome

Genomic gains and losses influence expression levels of genes located within the affected regions : a study on acute myeloid leukemias with trisomy 8, 11, or 13, monosomy 7, or deletion 5q