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出典(authority):フリー百科事典『ウィキペディア（Wikipedia）』「2012/11/10 17:16:29」(JST)

Tripamide (INN) is a diuretic.

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English Journal

Determination of Tripamide in human urine by high-performance liquid chromatography and high-performance liquid chromatography/electrospray ionization tandem mass spectrometry.

Kim Y1, Hwang J, Kim M, Lee W.
Rapid communications in mass spectrometry : RCM.Rapid Commun Mass Spectrom.2003;17(4):301-6.
Tripamide is a drug widely used in clinical practice for the treatment of hypertension and edema. This work evaluated a screening method for Tripamide and its urinary metabolites in human urine, using high-performance liquid chromatography diode-array detection (HPLC/DAD). Identification of these me
PMID 12569439

Anand A, Anand A.
Journal of the National Cancer Institute.J Natl Cancer Inst.1995 Jul 19;87(14):1086.
PMID 7616602

Multicenter private practice comparison of tripamide and hydrochlorothiazide in the treatment of hypertension.

Bope ET1, Adams RC, Brewer SC, Cairns CB, Fosnaugh NR, Leidheiser PC Jr, Platt CW, Polsley JS, Romaker RR, Scarbrough SD, et al.
Family practice research journal.Fam Pract Res J.1988 Summer;7(4):197-204.
One hundred fifty-nine patients with essential hypertension were randomly assigned to take 10 mg of tripamide or 50 mg of hydrochlorothiazide once a day for 12 weeks. Both drugs were equally effective in lowering both systolic and diastolic blood pressure in the supine (6/5 vs. 5/5 mm Hg) and standi
PMID 3075410

Hemodynamic characteristics of echocardiographic findings in hypertensive patients with negative U waves and effect of an antihypertensive drug, tripamide.

KISHIDA Hiroshi,TAKIGUCHI Fuyuko,SUGIKI Yuji,KUROKI Shinichi,TANAKA Takashi,SEINO Yasuhiko,SASAKI Hiroyuki,FUKUDA Jun,MATSUO Shogo
Ｊａｐａｎｅｓｅ　Ｈｅａｒｔ　Ｊｏｕｒｎａｌ 28(3), 377-386, 1987
… In addition, the effects of the antihypertensive agent tripamide were assessed in groups A and B. … Tripamide was administered to 14 patients. … In group A (6 patients receiving tripamide), left ventricular end-systolic and end-diastolic dimensions were significantly reduced by tripamide along with stroke volume and cardiac output. …
NAID 130000764879

Antihypertensive and hypothalamic depressant effects of tripamide in spontaneously hypertensive rats

Tripamide
Systematic (IUPAC) name
	3-(aminosulfonyl)-4-chloro-N-[(3aR,4S,7R,7aS)-octahydro-2H-4,7-methanoisoindol-2-yl]benzamide
Clinical data
AHFS/Drugs.com	International Drug Names
Pregnancy cat.	?
Legal status	℞ Prescription only
Routes	Oral
Identifiers
CAS number	73803-48-2
ATC code	None
PubChem	CID 636401
UNII	G36A0E9CVT
Chemical data
Formula	C16H20ClN3O3S
Mol. mass	369.86
	SMILES C1C[C@@H]2C[C@H]1[C@@H]3[C@H]2CN(C3)NC(=O)C4=CC(=C(C=C4)Cl)S(=O)(=O)N;
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