WordNet

a segment of DNA that can become integrated at many different sites along a chromosome (especially a segment of bacterial DNA that can be translocated as a whole) (同)jumping gene
an event capable of causing a mutation

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出典(authority):フリー百科事典『ウィキペディア（Wikipedia）』「2013/01/22 16:55:58」(JST)

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1. 肺炎桿菌感染症の微生物学および病因 microbiology and pathogenesis of klebsiella pneumoniae infection
2. 髄膜炎菌の微生物学および病理生物学 microbiology and pathobiology of neisseria meningitidis
3. 結核の自然史、微生物学、および病因 natural history microbiology and pathogenesis of tuberculosis
4. 遺伝学およびゲノミクスのためのツール：研究用に育種された遺伝子改変マウス tools for genetics and genomics specially bred and genetically engineered mice
5. バンコマイシン中等度耐性およびバンコマイシン耐性黄色ブドウ球菌感染症 vancomycin intermediate and vancomycin resistant staphylococcus aureus infections

Identifying novel mycobacterial stress associated genes using a random mutagenesis screen in Mycobacterium smegmatis.

Viswanathan G1, Joshi SV1, Sridhar A1, Dutta S1, Raghunand TR2.
Gene.Gene.2015 Dec 10;574(1):20-7. doi: 10.1016/j.gene.2015.07.063. Epub 2015 Jul 23.
Cell envelope associated components of Mycobacterium tuberculosis (M.tb) have been implicated in stress response, immune modulation and in vivo survival of the pathogen. Although many such factors have been identified, there is a large disparity between the number of genes predicted to be involved i
PMID 26211627

Buckle up! Transposon mutagenesis can differentiate melanoma drivers from their many passengers.

Farthing HM, Marie KL, Merlino G1.
Pigment cell & melanoma research.Pigment Cell Melanoma Res.2015 Nov;28(6):646-7. doi: 10.1111/pcmr.12416.
PMID 26314840

Random transposon mutagenesis of the Saccharopolyspora erythraea genome reveals additional genes influencing erythromycin biosynthesis.

Fedashchin A1, Cernota WH1, Gonzalez MC1, Leach BI1, Kwan N1, Wesley RK1, Weber JM2.
FEMS microbiology letters.FEMS Microbiol Lett.2015 Oct 13. pii: fnv180. [Epub ahead of print]
A single cycle of strain improvement was performed in Saccharopolyspora erythraea mutB and 15 genotypes influencing erythromycin production were found. Genotypes generated by transposon mutagenesis appeared in the screen at a frequency of ∼3%. Mutations affecting central metabolism and regulatory
PMID 26468041

Analysis of genes involved in exopolysaccharide production of Rothia mucilaginosa clinically isolated from a persistent apical periodontitis lesion

Fujihira Tomohiro,Yamane Kazuyoshi,Yoshida Masahiro,Nambu Takayuki,Hayashi Hiroyuki
Journal of Osaka Dental University 46(1), 157-164, 2012-04-00
… mucilaginosa, we isolated three meshwork-like structures defective mutants (strains FA1, FA7 and FA8) by random transposon mutagenesis using the Epicentre EZ-TN5 transposome system. … The transposon insertion region of strain FA1 was determined by PCR direct sequencing analysis. …
NAID 110009436547

Isolation of a biofilm-defective mutant of Actinomyces from a patient with gingivitis

Ogiso Kazuki,Nambu Takayuki,Kotsu Yoshio,Fukushima Hisanori,Ueda Masatoshi
Journal of Osaka Dental University 46(1), 91-99, 2012-04-00
… Using a random mutagenesis and biofilm assay for A. … The transposon in AOM0010 was inserted into the ANA2550 encoding 2-C-methyl-D-erythritol 4-phosphate (MEP) cytidylyltransferase, suggesting that the function of this gene is required for cell growth in A. … Unfortunately, this study could not enhance our understanding of Actinomyces biofilm formation, whereas the strategy of transposon mutagenesis was applicable to A. …
NAID 110009436540

Selection of Shewanella oneidensis MR-1 Gene-Knockout Mutants That Adapt to an Electrode-Respiring Condition

TAJIMA Nozomi,KOUZUMA Atsushi,HASHIMOTO Kazuhito [他],WATANABE Kazuya
Bioscience, biotechnology, and biochemistry 75(11), 2229-2233, 2011-11-23
… MR-1 that adapted to an electrode-respiring condition were selected from a random transposon-insertion mutant library to obtain active current-generating mutants and identify relevant cellular components. … Transposon-insertion sites in the isolated mutants were identified by inverse PCR coupled to sequence analyses. … Southern blotting using a transposon probe was also performed to detect mutants that grew abundantly on the electrode. …
NAID 10030397053