transient tachypnea of the newborn

新生児一過性多呼吸, TTN

WordNet

1. a special situation; "this thing has got to end"; "it is a remarkable thing"
2. a separate and self-contained entity
3. an action; "how could you do such a thing?"
4. an artifact; "how does this thing work?"
5. an entity that is not named specifically; "I couldnt tell what the thing was"
6. any attribute or quality considered as having its own existence; "the thing I like about her is ..."
7. a persistent illogical feeling of desire or aversion; "he has a thing about seafood"; "she has a thing about him"
8. a special abstraction; "a thing of the spirit"; "things of the heart"
9. a special objective; "the thing is to stay in bounds"
10. a statement regarded as an object; "to say the same thing in other terms"; "how can you say such a thing?"
11. an event; "a funny thing happened on the way to the..."
12. (physics) a short-lived oscillation in a system caused by a sudden change of voltage or current or load
13. one who stays for only a short time; "transient laborers"
14. recently born; "a newborn infant"
15. having just or recently arisen or come into existence; "new nations"; "with newborn fears" (同)new-sprung

PrepTutorEJDIC

1. 〈C〉(形のある)『物』,物体;(生物に対しての)『無生物』 / 〈C〉(形のない)『もの』,事,事柄,でき事 / 《複数形で》事情,事態,状勢,状況 / 《複数形で》(すべての)事物,事柄 / 《通例 the~》(努力・活動などの)目的,目標 / 〈C〉衣服,衣類・《one's things》持ち物,所持品,身の回り品 / 《複数形で》道具,用具・〈C〉《親愛・哀れみ・軽べつなどの感情をこめて》人,者,やつ / 《the~》《話》(…の)流行《+in+名》
2. 《所有・所属》…『の』,…のものである,…に属する・《材料・要素》…『でできた』,から成る・《部分》…『の』[『中の』] ・《数量・単位・種類を表す名詞に付いて》…の・《原因・動機》…『で』,のために(because of) ・《主格関係》…『の』,による,によって・《目的格関係》…『を』,の・《同格関係》…『という』・《関係・関連》…『についての』[『の』],の点で・《抽象名詞などと共に》…の[性質をもつ] ・《『It is』+『形』+『of』+『名』+『to』 doの形で,ofの後の名詞を意味上の主語として》・《分離》…『から』・《起原・出所》…『から』[『の』](out of) ・《『名』+『of』+『a』(『an』)+『名』の形で》…のような・《『名』+『of』+『mine』(『yours, his』など独立所有格)の形で》…の…・《時》(1)《副詞句を作って》…に《形容詞句を作って》…の・《時刻》《米》…前(to,《米》before)
3. 《前述の名詞または文脈でそれと分かる名詞に付けて》『その』,あの,名の / 《唯一の事物に付けて》 / 《方角・自然現象に付けて》 / 《用具・楽器・特定の病気などに付けて》 / 《修飾吾[句]を伴う名詞に付けて》 / 《単数普通名詞に付けて》(1)《種族全体》…『というもの』 / 《複数名詞または集合名詞に付けて》 / 《単位》『…につき;…単位[で]』 / 《身体の一部に付けて,所有格に代わる》 / 《形容詞に付けて》 / 《固有名詞に付けて》 / 《強意用法に》『随一の』,典型的な / 《「the+比較級,the+比較級」の形で》『…すればするほどそれだけ』 / 《比較級の前に》(…につれて,のために)『それだけ』,ますます
4. (また transitory)一時の,つかの間の,はかない / (人が)短期滞在の / (ホテルなどの)短期滞在客
5. 生まれたばかりの / 生まれ変わった,再生の

Wikipedia preview

出典(authority):フリー百科事典『ウィキペディア（Wikipedia）』「2016/05/12 18:21:32」(JST)

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Transient tachypnea of the newborn
Classification and external resources
Specialty	pediatrics
ICD-10	P22.1
ICD-9-CM	770.6
DiseasesDB	32373
MedlinePlus	007233
eMedicine	ped/2597 radio/710

Transient tachypnea of the newborn (TTN, TTNB, or "transitory tachypnea of newborn") is a respiratory problem that can be seen in the newborn shortly after delivery. Amongst causes of respiratory distress in term neonates, it is the most common. It consists of a period of rapid breathing (higher than the normal range of 30-60 times per minute). It is likely due to retained lung fluid. It is most often seen in 35+ week gestation babies who are delivered by caesarian section without labor. Usually, this condition resolves over 24–48 hours. Treatment is supportive and may include supplemental oxygen and antibiotics. The chest x-ray shows hyperinflation of the lungs including prominent pulmonary vascular markings, flattening of the diaphragm, and fluid in the horizontal fissure of the right lung.

Pathophysiology

1. Due to the higher incidence of TTN in newborns delivered by caesarean section, it has been postulated that TTN could result from a delayed absorption of fetal lung fluid from the pulmonary lymphatic system. The increased fluid in the lungs leads to increased airway resistance and reduced lung compliance. It is thought this could be from lower levels of circulating catecholamines after a caesarean section, which are believed to be necessary to alter the function of the ENaC channel to absorb excess fluid from the lungs.
2. Pulmonary immaturity has also been proposed as a causative factor. Levels of phosphatidylglycerol (an indicator of lung maturity) were found to be negative in certain newborns.
3. Mild surfactant deficiency has also been suggested as a causative factor.

Clinical evaluation

TTN is a diagnosis of exclusion as it is a benign condition that can have symptoms and signs similar to more serious conditions, such as respiratory distress syndrome. A chest X-ray may show a radiopaque line - fluid - in the horizontal fissure of the right lung, fluid infiltrate throughout alveoli or fluid in individual lung lobes.

References

UpToDate Contents

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• 1. 新生児の一過性頻呼吸 transient tachypnea of the newborn
• 2. 新生児呼吸促迫の概要：移行の障害 overview of neonatal respiratory distress disorders of transition
• 3. 新生児における呼吸促迫症候群の病態生理および臨床症状 pathophysiology and clinical manifestations of respiratory distress syndrome in the newborn
• 4. 糖尿病の母親の小児 infant of a diabetic mother
• 5. 新生児におけるチアノーゼの概要 overview of cyanosis in the newborn

English Journal

• Effect of Meconium-Stained Amniotic Fluid on Perinatal Complications in Low-Risk Pregnancies at Term.

• Hiersch L1, Krispin E1, Aviram A1, Wiznitzer A1, Yogev Y1, Ashwal E1.
• American journal of perinatology.Am J Perinatol.2015 Oct 19. [Epub ahead of print]
• Objective This study aims to determine the impact of meconium-stained amniotic fluid (MSAF) in low-risk pregnancies at term on pregnancy outcome. Study Design A retrospective cohort study of women with MSAF during labor who delivered in a tertiary hospital at 37 to 41+6 weeks of gestation (2007-
• PMID 26479168

• Risk assessment for neonatal RDS/TTN using gestational age and the amniotic lamellar body count in twin pregnancies.

• Tsuda H1, Hirakawa A2, Kotani T3, Sumigama S3, Mano Y3, Nakano T3, Imai K3, Kawabata I4, Takahashi Y4, Iwagaki S4, Kikkawa F3.
• Clinica chimica acta; international journal of clinical chemistry.Clin Chim Acta.2015 Oct 19. pii: S0009-8981(15)30016-4. doi: 10.1016/j.cca.2015.10.013. [Epub ahead of print]
• PMID 26477481

• Predictors of adverse neonatal outcomes in intrahepatic cholestasis of pregnancy.

• Kawakita T1, Parikh LI2, Ramsey PS3, Huang CC4, Zeymo A4, Fernandez M5, Smith S6, Iqbal SN2.
• American journal of obstetrics and gynecology.Am J Obstet Gynecol.2015 Oct;213(4):570.e1-8. doi: 10.1016/j.ajog.2015.06.021. Epub 2015 Jun 10.
• OBJECTIVE: We sought to determine predictors of adverse neonatal outcomes in women with intrahepatic cholestasis of pregnancy (ICP).STUDY DESIGN: This study was a multicenter retrospective cohort study of all women diagnosed with ICP across 5 hospital facilities from January 2009 through December 20
• PMID 26071912

Japanese Journal

• 臨床研究・症例報告 先天性全身性カンジダ症と鑑別を要した新生児一過性多呼吸を伴った先天性皮膚カンジダ症の1例

• 小児科臨床 69(3), 455-459, 2016-03
• NAID 40020740910

• Republication: Two Premature Neonates of Congenital Syphilis with Severe Clinical Manifestations

• Tropical Medicine and Health 43(3), 165-170, 2015
• NAID 130005102108

• Republication: Two premature neonates of congenital syphilis with severe clinical manifestations

• Tropical Medicine and Health advpub(0), 2015
• NAID 130005076137

Related Links

• Transient Tachypnea of the Newborn - Diseases & Conditions ...

Transient Tachypnea of the Newborn. Transient tachypnea of the newborn (TTN) is a self-limited disease commonly seen in neonates throughout the world and is encountered by all physicians who take care of newborn ...

• Transient Tachypnea of the Newborn (TTN) - KidsHealth ...

For some newborns, the first few breaths of life may be more rapid and labored than normal because of a lung condition called transient tachypnea of the newborn (TTN). ... Some newborns' breathing during the first hours of life is ...

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★リンクテーブル★

リンク元	「新生児一過性多呼吸」「TTNB」「TTN」
関連記事	「transient」「newborn」「thing」

「新生児一過性多呼吸」

　　[★]

英

transient tachypnea of the newborn, TTN

関

新生児一過性頻呼吸

病因

• 肺胞水の吸収遅延

• 通常、分娩により羊水の産生が低下する。正常例では生後30分に75%の例で羊水の残存が認められるが、6時間後には肺胞より吸収され認められなくなる。

疫学

• 適応障害、予定帝王切開児

症状

• チアノーゼ、多呼吸、陥没呼吸、呻吟

診断

• 臨床所見

• 生後6時間以内に発症し、症状が12時間以上持続する。呼吸数は60回/分以上。

• 胸部X線像
• 除外診断となる

• 呼吸窮迫症候群、胎便吸引症候群や肺炎などの他の疾患を除外できるかどうか

検査

• 胸部X線像

• wet lung様所見

治療

• 酸素投与、人工換気療法、気管内洗浄　

「TTNB」

　　[★] 新生児一過性多呼吸 transient tachypnea of the newborn = TTN

「TTN」

　　[★] 新生児一過性多呼吸, transient tachypnea of the newborn

「transient」

　　[★]

• adj.

• 一時の、瞬間的な、束の間の、一過性の、過渡的な。はかない、無常な
• しばらくとどまっては移動する、滞在の短い。

• n.

• 一過性の人/もの。短期滞在客。移動労働者/渡り労働者。浮浪者/放浪者。

関

ephemeral, migrant, transient response, transiently, transitory

　 　 　

「newborn」

　　[★]

• n.

• 新生児

• adj.

• 新生児の

関

neonatal、neonate、newborn animal、newborn infant

　 　 　

「thing」

　　[★]