WordNet

to conduct a test or investigation; "We are experimenting with the new drug in order to fight this disease"
the act of conducting a controlled test or investigation (同)experimentation
a venture at something new or different; "as an experiment he decided to grow a beard"
the testing of an idea; "it was an experiment in living"; "not all experimentation is done in laboratories" (同)experimentation
try something new, as in order to gain experience; "Students experiment sexually"; "The composer experimented with a new style" (同)try out

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1. 進行非小細胞肺癌に対する遺伝子型による個別治療 personalized genotype directed therapy for advanced non small cell lung cancer
2. マウス遺伝子：育種戦略と遺伝子工学 mouse genetics breeding strategies and genetic engineering
3. 放射線誘発性甲状腺癌 radiation induced thyroid cancer
4. メンデルランダム化 mendelian randomization
5. 炎症性乳癌：病理および分子学的病因 inflammatory breast cancer pathology and molecular pathogenesis

Transarterial embolization combined with RNA interference targeting hypoxia-inducible factor-1α for hepatocellular carcinoma: a preliminary study of rat model.

Ni JY1, Xu LF2, Wang WD1, Huang QS1, Sun HL1, Chen YT1.
Journal of cancer research and clinical oncology.J Cancer Res Clin Oncol.2017 Feb;143(2):199-207. doi: 10.1007/s00432-016-2237-x. Epub 2016 Sep 16.
PURPOSE: To study whether transarterial embolization (TAE) with RNA interference (RNAi) targeting hypoxia-inducible factor-1α (HIF-1α) can improve efficacy of TAE in treating hepatocellular carcinoma (HCC).MATERIALS AND METHODS: CBRH-7919 rat hepatoma cell line was used and HCC models of rats were
PMID 27638772

Quantification and simultaneous evaluation of the bioactivity of antibody produced in CHO cell culture-The use of the ectodomain of FcγRI and surface plasmon resonance-based biosensor.

Dorion-Thibaudeau J1, Durocher Y2, De Crescenzo G3.
Molecular immunology.Mol Immunol.2017 Feb;82:46-49. doi: 10.1016/j.molimm.2016.12.017. Epub 2016 Dec 21.
A surface plasmon resonance (SPR)-based assay has been developed in order to quantify the monoclonal antibody (Mab) Trastuzumab within the supernatant of a mammalian cell culture using the ectodomain of FcγRI (CD64) and confirm Mab bioactivity, i.e. binding to its antigen Her2, in a single biosensi
PMID 28012362

Suppression of Carboxylesterases by Imatinib Mediated by the Downregulation of Pregnane X Receptor.

Luo W1,2, Xin Y1,2, Zhao X3, Zhang F2, Liu C4, Fan H4, Xi T2, Xiong J1.
British journal of pharmacology.Br J Pharmacol.2017 Jan 27. doi: 10.1111/bph.13731. [Epub ahead of print]
BACKGROUND AND PURPOSE: Imatinib mesylate (IM) is first-line anti-chronic myeloid leukemia (CML) therapy as a specific inhibitor of BCR-ABL tyrosine kinase. IM in combination with other drugs has been widely applied in CML treatment, thus the influence of IM on drug metabolism enzymes (DMEs) is cruc
PMID 28128444

TGF-β1 INDUCES FIBROBLAST PROLIFERATION PARTLY THROUGH ACTIBATION OF RaF/MEK/ERK SIGNALING PATHWAY BY INHIBITION OF RAF-KINASE INHIBITOR PROTEIN EXPRESSION