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出典(authority):フリー百科事典『ウィキペディア(Wikipedia)』「2013/04/15 11:14:24」(JST)

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  • Luciferase inhibition by a novel naphthoquinone.
  • Bedford R, Lepage D, Hoffmann R, Kennedy S, Gutschenritter T, Bull L, Sujijantarat N, Dicesare JC, Sheaff RJ.SourceDepartment of Chemistry and Biochemistry, The University of Tulsa, Tulsa, OK, United States.
  • Journal of photochemistry and photobiology. B, Biology.J Photochem Photobiol B.2012 Feb 6;107:55-64. Epub 2011 Dec 8.
  • The novel naphthoquinone 12,13-dihydro-N-methyl-6,11,13-trioxo-5H-benzo[4,5]cyclohepta[1,2-b]naphthalen-5,12-imine (hereafter called TU100) was created as a potential chemotherapeutic agent. Previous work showed it is an irreversible inhibitor of type I and II topoisomerases that alkylates specific
  • PMID 22197716


  • Molecular Analysis of Levofloxacin-resistant Streptococcus pneumoniae in Japan
  • SHOJI Hisashi,TAKUMA Takahiro,NIKI Yoshihito
  • The Showa University Journal of Medical Sciences 26(3), 181-190, 2014
  • … Quinolone resistance has been attributed to amino acid mutations in the type II topoisomerases of pathogens. … We also sequenced the quinolone resistance-determining regions (QRDRs) in type II topoisomerases and analyzed the relationship between minimum inhibitory concentration (MIC) and six specific mutations (Ser81 or Glu85 in GyrA, Asp435 in GyrB, Ser79 or Asp83 in ParC, and Asp435 in ParE). …
  • NAID 130004841522
  • Inhibitory effects of catechin derivatives on mammalian DNA polymerase and topoisomerase activities and mouse one-cell zygote development(BIOCHEMICAL ENGINEERING)
  • Yoshida Naoko,Kuriyama Isoko,Yoshida Hiromi [他],Mizushina Yoshiyuki
  • Journal of bioscience and bioengineering 115(3), 303-309, 2013-03
  • … In this study, the inhibitory activities against DNA polyinerases (pols) and DNA topoisomerases (topos) by eight major green tea catechin derivatives (flavan-3-ols) were investigated. …
  • NAID 110009596105