WordNet
- a soft thin (usually translucent) paper (同)tissue_paper
- part of an organism consisting of an aggregate of cells having a similar structure and function
- writing done with a typewriter (同)typewriting
PrepTutorEJDIC
- 〈U〉〈C〉(生物体の)『組織』 / 〈U〉〈C〉『薄織物』 / 〈U〉〈C〉水を吸収する柔らかな薄紙 / 〈C〉カーボンコピー用薄紙 / 〈C〉《a ~》(…を)織り交ぜて作ったもの《+of+名》 / =tissue paper
Wikipedia preview
出典(authority):フリー百科事典『ウィキペディア(Wikipedia)』「2012/05/28 11:11:04」(JST)
[Wiki en表示]
Tissue typing is a procedure in which the tissues of a prospective donor and recipient are tested for compatibility prior to transplantation. An embryo can be tissue typed to ensure that the embryo implanted can be a cord-blood stem cell donor for a sick sibling.[1]
One technique of tissue typing, "mixed leukocyte reaction", is performed by culturing lymphocytes from the donor together with those from the recipient.[2]
Another technique, known as a micro-cytotoxicity assay, utilizes serum with known anti-HLA antibodies that recognize particular HLA loci (HLA-A, HLA-B, HLA-C, HLA-DP, HLA-DQ, HLA-DR) in order to match genetically similar individuals in hopes of performing a tissue transplantation. In this technique a donor's blood cells are MHC typed by mixing them with serum containing the anti-HLA antibodies. If the antibodies recognize their epitope on the MHC then complement activation occurs and the cell will be osmotically lysed. Lysis results in the cell taking up a dye (trypan blue). This allows identification of cell's MHC indirectly based on the specificity of the known antibodies in the serum.
See also
References
- ^ "Designing Donors". Shaun D. Pattinson, Faculty of Law and Sheffield Institute of Biotechnological Law and Ethics, University of Sheffield. link
- ^ MHC
External links
- How Preimplantation tissue typing works, HFEA website
- MeSH Tissue+typing
- http://www.stanford.edu/dept/HPS/transplant/html/tt_1.html
- http://www.bchealthguide.org/kbase/topic/medtest/hw40261/descrip.htm
UpToDate Contents
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English Journal
- Infusion of leukocytes from HLA haplo-identical familial donors as an adjuvant in the HLH-2004 protocol to treat the virus-associated adult hemophagocytic lymphohistiocytosis: a retrospective study of 26 patients.
- Zhang H1, Dai Z1, Yang N1, Wang J1, He A1, Wang J1, Zhang Y1, Meng S1, Wang B1, Sun R2, Zhang W3.
- Annals of hematology.Ann Hematol.2018 Feb;97(2):319-326. doi: 10.1007/s00277-017-3174-8. Epub 2017 Nov 12.
- PMID 29130133
- Reconstitution of Th17, Tc17 and Treg cells after paediatric haematopoietic stem cell transplantation: Impact of interleukin-7.
- Kielsen K1, Ryder LP2, Lennox-Hvenekilde D3, Gad M4, Nielsen CH5, Heilmann C6, Ifversen M6, Pedersen AE3, Müller K7.
- Immunobiology.Immunobiology.2018 Feb;223(2):220-226. doi: 10.1016/j.imbio.2017.10.023. Epub 2017 Oct 9.
- PMID 29033080
Japanese Journal
- Human leukocyte antigen (HLA)-B54,Cw1を有し,脳生検により,神経好中球病がうたがわれた1例
- 中西 悦郎,澤村 正典,丸浜 伸一朗,山田 浩,金 剛,原田 清
- 臨床神経学 55(1), 13-17, 2015
- 症例は72歳女性である.2011年5月下旬から亜急性に右片麻痺,失語症状が出現した.血液検査,脳脊髄液検査,13F-FDG-PET,頭部MRIの結果から,血管内リンパ腫,悪性リンパ腫がうたがわれ,脳生検術が施行された.病理所見では悪性腫瘍を示唆する所見はなく,血管周囲腔を中心に好中球や組織球の浸潤をみとめた.ステロイド療法を施行したところ著効し,human leukocyte …
- NAID 130004921294
- Late-onset Congenital Adrenal Hyperplasia with Cushing Syndrome
- , , , , , ,
- Internal Medicine 53(17), 1955-1959, 2014
- Although hirsutism is classically part of the clinical presentation of polycystic ovarian syndrome (PCOS), congenital adrenal hyperplasia and Cushing's syndrome (CS), CS associated with underlying lat …
- NAID 130004685033
Related Links
- tissue typingとは。意味や和訳。[U]医学(移植組織の適合性を決定する)組織適合試験. - goo辞書は国語、英和、和英、中国語、百科事典等からまとめて探せる辞書検索サービスです。
- Tissue Typing Definition Tissue typing is a group of procedures that determines the type of histocompatibility antigens on a person's cells or tissues. This procedure is typically used prior to transplantation of tissues or organs. Purpose ...
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- 英
- histocompatibility test
- 同
- 組織タイピング tissue typing
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- 英
- tissue typing
- 関
- 組織適合試験
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